Mycobacterium tuberculosis Pathogenesis, Infection Prevention and Treatment
Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium tuberculosis (MTB) and it represents a persistent public health threat for a number of complex biological and sociological reasons. According to the most recent Global Tuberculosis Report (2019) edited by the World Heal...
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| Materialtyp: | Online |
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| Språk: | engelska |
| Utgiven: |
MDPI - Multidisciplinary Digital Publishing Institute
2021
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| Länkar: | ONIX_20210501_9783039366583_899 |
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| _version_ | 1869524180087603200 |
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| collection | Directory of Open Access Books |
| description | Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium tuberculosis (MTB) and it represents a persistent public health threat for a number of complex biological and sociological reasons. According to the most recent Global Tuberculosis Report (2019) edited by the World Health Organization (WHO), TB is considered the ninth cause of death worldwide and the leading cause of mortality by a single infectious agent, with the highest rate of infections and death toll rate mostly concentrated in developing and low-income countries. We present here the editorial section to the Special Issue entitled “Mycobacterium tuberculosis Pathogenesis, Infection Prevention and Treatment” that includes 7 research articles and a review. The scientific contributions included in the Special Issue mainly focus on the characterization of MTB strains emerging in TB endemic countries as well as on multiple mechanisms adopted by the bacteria to resist and to adapt to antitubercular therapies. |
| format | Online |
| id | doab-20.500.12854ir-69153 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-691532024-03-28T03:33:40Z Mycobacterium tuberculosis Pathogenesis, Infection Prevention and Treatment Ferraris, Davide Maria Miggiano, Riccardo Rizzi, Menico Mycobacterium tuberculosis line probe assay second-line drugs drug resistance XDR-TB MDR-TB omics analysis TB treatment system analysis Beijing B0/W148 Mycobacterium smegmatis imidazo[1,2-b][1,2,4,5]tetrazine MmpS5-MmpL5 efflux drug discovery tuberculosis immune activation HLA-DR CD38 treatment response Mycobacterium macrophage apoptosis effector cytokine microRNA Beijing genotype Central Asia Outbreak murine infection model Virulence pre-XDR-TB Mycobacterium avium unique metabolic pathways subtractive genomics drug target uncharacterized proteins BM-MSCs Mtb bone-homing stem cell niche latent tuberculosis relapse liposomes M. tuberculosis host-pathogen interactions immune response antitubercular drug discovery antitubercular treatments IL-18 IL-18BP IL-18R gene expression thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium tuberculosis (MTB) and it represents a persistent public health threat for a number of complex biological and sociological reasons. According to the most recent Global Tuberculosis Report (2019) edited by the World Health Organization (WHO), TB is considered the ninth cause of death worldwide and the leading cause of mortality by a single infectious agent, with the highest rate of infections and death toll rate mostly concentrated in developing and low-income countries. We present here the editorial section to the Special Issue entitled “Mycobacterium tuberculosis Pathogenesis, Infection Prevention and Treatment” that includes 7 research articles and a review. The scientific contributions included in the Special Issue mainly focus on the characterization of MTB strains emerging in TB endemic countries as well as on multiple mechanisms adopted by the bacteria to resist and to adapt to antitubercular therapies. 2021-05-01T15:42:18Z 2021-05-01T15:42:18Z 2020 book ONIX_20210501_9783039366583_899 9783039366583 9783039366590 https://directory.doabooks.org/handle/20.500.12854/69153 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/2925 https://mdpi.com/books/pdfview/book/2925 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03936-659-0 10.3390/books978-3-03936-659-0 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783039366583 9783039366590 128 Basel, Switzerland open access |
| spellingShingle | Mycobacterium tuberculosis line probe assay second-line drugs drug resistance XDR-TB MDR-TB omics analysis TB treatment system analysis Beijing B0/W148 Mycobacterium smegmatis imidazo[1,2-b][1,2,4,5]tetrazine MmpS5-MmpL5 efflux drug discovery tuberculosis immune activation HLA-DR CD38 treatment response Mycobacterium macrophage apoptosis effector cytokine microRNA Beijing genotype Central Asia Outbreak murine infection model Virulence pre-XDR-TB Mycobacterium avium unique metabolic pathways subtractive genomics drug target uncharacterized proteins BM-MSCs Mtb bone-homing stem cell niche latent tuberculosis relapse liposomes M. tuberculosis host-pathogen interactions immune response antitubercular drug discovery antitubercular treatments IL-18 IL-18BP IL-18R gene expression thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Mycobacterium tuberculosis Pathogenesis, Infection Prevention and Treatment |
| title | Mycobacterium tuberculosis Pathogenesis, Infection Prevention and Treatment |
| title_full | Mycobacterium tuberculosis Pathogenesis, Infection Prevention and Treatment |
| title_fullStr | Mycobacterium tuberculosis Pathogenesis, Infection Prevention and Treatment |
| title_full_unstemmed | Mycobacterium tuberculosis Pathogenesis, Infection Prevention and Treatment |
| title_short | Mycobacterium tuberculosis Pathogenesis, Infection Prevention and Treatment |
| title_sort | mycobacterium tuberculosis pathogenesis infection prevention and treatment |
| topic | Mycobacterium tuberculosis line probe assay second-line drugs drug resistance XDR-TB MDR-TB omics analysis TB treatment system analysis Beijing B0/W148 Mycobacterium smegmatis imidazo[1,2-b][1,2,4,5]tetrazine MmpS5-MmpL5 efflux drug discovery tuberculosis immune activation HLA-DR CD38 treatment response Mycobacterium macrophage apoptosis effector cytokine microRNA Beijing genotype Central Asia Outbreak murine infection model Virulence pre-XDR-TB Mycobacterium avium unique metabolic pathways subtractive genomics drug target uncharacterized proteins BM-MSCs Mtb bone-homing stem cell niche latent tuberculosis relapse liposomes M. tuberculosis host-pathogen interactions immune response antitubercular drug discovery antitubercular treatments IL-18 IL-18BP IL-18R gene expression thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| topic_facet | Mycobacterium tuberculosis line probe assay second-line drugs drug resistance XDR-TB MDR-TB omics analysis TB treatment system analysis Beijing B0/W148 Mycobacterium smegmatis imidazo[1,2-b][1,2,4,5]tetrazine MmpS5-MmpL5 efflux drug discovery tuberculosis immune activation HLA-DR CD38 treatment response Mycobacterium macrophage apoptosis effector cytokine microRNA Beijing genotype Central Asia Outbreak murine infection model Virulence pre-XDR-TB Mycobacterium avium unique metabolic pathways subtractive genomics drug target uncharacterized proteins BM-MSCs Mtb bone-homing stem cell niche latent tuberculosis relapse liposomes M. tuberculosis host-pathogen interactions immune response antitubercular drug discovery antitubercular treatments IL-18 IL-18BP IL-18R gene expression thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| url | ONIX_20210501_9783039366583_899 |