Male Germline Chromatin

Spermatogenesis requires radical restructuring of germline chromatin at multiple stages, involving coordinated waves of DNA methylation/demethylation, histone modification, and the replacement and removal that occurs before, during, and after meiosis. This Special Issue will draw together papers tha...

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יצא לאור: MDPI - Multidisciplinary Digital Publishing Institute 2021
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גישה מקוונת:ONIX_20210501_9783039368549_912
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collection Directory of Open Access Books
description Spermatogenesis requires radical restructuring of germline chromatin at multiple stages, involving coordinated waves of DNA methylation/demethylation, histone modification, and the replacement and removal that occurs before, during, and after meiosis. This Special Issue will draw together papers that address all aspects of chromatin organization and dynamics in the male germ line, in humans, and in model organisms. In particular, we will invite authors to discuss novel methods for studying germline chromatin structure, the interplay between chromatin structure and susceptibility to DNA damage and mutation, chromatin modifications associated with epigenetic inheritance in the early embryo, and the impact this work has for understanding natural fertility and improving assisted reproduction techniques.
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institution Directory of Open Access Books
language eng
publishDate 2021
publishDateRange 2021
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publisher MDPI - Multidisciplinary Digital Publishing Institute
publisherStr MDPI - Multidisciplinary Digital Publishing Institute
record_format ojs
spelling doab-20.500.12854ir-691662024-03-28T03:33:44Z Male Germline Chromatin Griffin, Darren Ellis, Peter mouse sperm chromatin chromosome organization nuclear-3D-parameters spermiogenesis chromatin remodeling DNA double-strand breaks genetic instability mutations sperm DNA damage DNA fragmentation infertility assisted reproduction miscarriage implantation nuclear organization sperm morphometrics chromosome painting nucleoli NOR chromosome associations meiotic prophase spermatocytes Mus m. domesticus Robertsonian chromosomes chromosome translocation Y chromosome testis spermatogenesis SLY mouse oxidative stress reactive oxygen species chromatin DNA oxidation male infertility spermatozoa chromosomes chromosome territories centromeres male germ cells telomeres reproductive aging nuclear organisation epigenetic inheritance histone retention in vitro fertilisation thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Spermatogenesis requires radical restructuring of germline chromatin at multiple stages, involving coordinated waves of DNA methylation/demethylation, histone modification, and the replacement and removal that occurs before, during, and after meiosis. This Special Issue will draw together papers that address all aspects of chromatin organization and dynamics in the male germ line, in humans, and in model organisms. In particular, we will invite authors to discuss novel methods for studying germline chromatin structure, the interplay between chromatin structure and susceptibility to DNA damage and mutation, chromatin modifications associated with epigenetic inheritance in the early embryo, and the impact this work has for understanding natural fertility and improving assisted reproduction techniques. 2021-05-01T15:42:50Z 2021-05-01T15:42:50Z 2020 book ONIX_20210501_9783039368549_912 9783039368549 9783039368556 https://directory.doabooks.org/handle/20.500.12854/69166 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/2938 https://mdpi.com/books/pdfview/book/2938 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03936-855-6 10.3390/books978-3-03936-855-6 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783039368549 9783039368556 144 Basel, Switzerland open access
spellingShingle mouse sperm chromatin
chromosome organization
nuclear-3D-parameters
spermiogenesis
chromatin remodeling
DNA double-strand breaks
genetic instability
mutations
sperm DNA damage
DNA fragmentation
infertility
assisted reproduction
miscarriage
implantation
nuclear organization
sperm
morphometrics
chromosome painting
nucleoli
NOR
chromosome associations
meiotic prophase
spermatocytes
Mus m. domesticus
Robertsonian chromosomes
chromosome translocation
Y chromosome
testis
spermatogenesis
SLY
mouse
oxidative stress
reactive oxygen species
chromatin
DNA oxidation
male infertility
spermatozoa
chromosomes
chromosome territories
centromeres
male germ cells
telomeres
reproductive aging
nuclear organisation
epigenetic inheritance
histone retention
in vitro fertilisation
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
Male Germline Chromatin
title Male Germline Chromatin
title_full Male Germline Chromatin
title_fullStr Male Germline Chromatin
title_full_unstemmed Male Germline Chromatin
title_short Male Germline Chromatin
title_sort male germline chromatin
topic mouse sperm chromatin
chromosome organization
nuclear-3D-parameters
spermiogenesis
chromatin remodeling
DNA double-strand breaks
genetic instability
mutations
sperm DNA damage
DNA fragmentation
infertility
assisted reproduction
miscarriage
implantation
nuclear organization
sperm
morphometrics
chromosome painting
nucleoli
NOR
chromosome associations
meiotic prophase
spermatocytes
Mus m. domesticus
Robertsonian chromosomes
chromosome translocation
Y chromosome
testis
spermatogenesis
SLY
mouse
oxidative stress
reactive oxygen species
chromatin
DNA oxidation
male infertility
spermatozoa
chromosomes
chromosome territories
centromeres
male germ cells
telomeres
reproductive aging
nuclear organisation
epigenetic inheritance
histone retention
in vitro fertilisation
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
topic_facet mouse sperm chromatin
chromosome organization
nuclear-3D-parameters
spermiogenesis
chromatin remodeling
DNA double-strand breaks
genetic instability
mutations
sperm DNA damage
DNA fragmentation
infertility
assisted reproduction
miscarriage
implantation
nuclear organization
sperm
morphometrics
chromosome painting
nucleoli
NOR
chromosome associations
meiotic prophase
spermatocytes
Mus m. domesticus
Robertsonian chromosomes
chromosome translocation
Y chromosome
testis
spermatogenesis
SLY
mouse
oxidative stress
reactive oxygen species
chromatin
DNA oxidation
male infertility
spermatozoa
chromosomes
chromosome territories
centromeres
male germ cells
telomeres
reproductive aging
nuclear organisation
epigenetic inheritance
histone retention
in vitro fertilisation
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
url ONIX_20210501_9783039368549_912