Osseointegrated Oral implants
In the past, osseointegration was regarded to be a mode of implant anchorage that simulated a simple wound healing phenomenon. Today, we have evidence that osseointegration is, in fact, a foreign body reaction that involves an immunologically derived bony demarcation of an implant to shield it off f...
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MDPI - Multidisciplinary Digital Publishing Institute
2021
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| Liŋkkat: | ONIX_20210501_9783039366408_931 |
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| description | In the past, osseointegration was regarded to be a mode of implant anchorage that simulated a simple wound healing phenomenon. Today, we have evidence that osseointegration is, in fact, a foreign body reaction that involves an immunologically derived bony demarcation of an implant to shield it off from the tissues. Marginal bone resorption around an oral implant cannot be properly understood without realizing the foreign body nature of the implant itself. Whereas the immunological response as such is positive for implant longevity, adverse immunological reactions may cause marginal bone loss in combination with combined factors. Combined factors include the hardware, clinical handling as well as patient characteristics that, even if each one of these factors only produce subliminal trauma, when acting together they may result in loss of marginal bone. The role of bacteria in the process of marginal bone loss is smaller than previously believed due to combined defense mechanisms of inflammation and immunological reactions, but if the defense is failing we may see bacterially induced marginal bone loss as well. However, problems with loss of marginal bone threatening implant survival remains relatively uncommon; we have today 10 years of clinical documentation of five different types of implant displaying a failure rate in the range of only 1 to 4 %. |
| format | Online |
| id | doab-20.500.12854ir-69185 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-691852024-03-31T13:08:31Z Osseointegrated Oral implants Albrektsson, Tomas osseointegration dental implant peri-implantitis ligature-induced peri-implantitis aseptic loosening systematic review immune system biomaterials foreign body reaction in vivo study oral implants marginal bone loss immunomodulation mechanotransduction Crestal bone loss osseosufficiency osseoseparation photoacoustic ultrasound brain–bone axis overloading radiography CBCT (cone beam computerized tomography) osteogenesis osteotomy bone healing bone chips drilling tool design fused deposition modeling polyether ether ketone biocomposite orthopedic implant oral implant mechanical properties wettability topography biocompatibility cell adhesion peri-implant endosseous healing dental implantation alveolar bone loss alveolar bone remodeling/regeneration bone biology finite element analysis (FEA) biomechanics cell plasticity dental implants electron microscopy scanning transmission electron microscopy bone-implant interface bone loss overdenture implant survival implant surface soft tissue split-mouth design oral health-related quality of life patient-reported outcome measures biomaterial bone immune implant healing titanium PEEK Cu micro-RNA microarray predictive biomarker epigenomics mucositis diagnosis over-treatment iatrogenic damage abutment height subcrestal implants implant insertion depth vertical mucosal thickness biological width implant installation anchorage technique histology intraosseous temperature finite element model ligature induced peri-implantitis arthroplasty replacement hip hypersensitivity contact allergy and immunology cytokines Interleukin-8 surface properties materials testing implant contamination scanning electron microscopy energy-dispersive X-ray spectrometry convergence clinical study biofilm infection perio-prosthetic joint infection periimplantitis electrolytic cleaning n/a zirconia insertion bone–implant interface heat bone damage early loss augmentation air flow re-osseointegration classification of bone defects dog study thema EDItEUR::M Medicine and Nursing In the past, osseointegration was regarded to be a mode of implant anchorage that simulated a simple wound healing phenomenon. Today, we have evidence that osseointegration is, in fact, a foreign body reaction that involves an immunologically derived bony demarcation of an implant to shield it off from the tissues. Marginal bone resorption around an oral implant cannot be properly understood without realizing the foreign body nature of the implant itself. Whereas the immunological response as such is positive for implant longevity, adverse immunological reactions may cause marginal bone loss in combination with combined factors. Combined factors include the hardware, clinical handling as well as patient characteristics that, even if each one of these factors only produce subliminal trauma, when acting together they may result in loss of marginal bone. The role of bacteria in the process of marginal bone loss is smaller than previously believed due to combined defense mechanisms of inflammation and immunological reactions, but if the defense is failing we may see bacterially induced marginal bone loss as well. However, problems with loss of marginal bone threatening implant survival remains relatively uncommon; we have today 10 years of clinical documentation of five different types of implant displaying a failure rate in the range of only 1 to 4 %. 2021-05-01T15:43:17Z 2021-05-01T15:43:17Z 2020 book ONIX_20210501_9783039366408_931 9783039366408 9783039366415 https://directory.doabooks.org/handle/20.500.12854/69185 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/2957 https://mdpi.com/books/pdfview/book/2957 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03936-641-5 10.3390/books978-3-03936-641-5 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783039366408 9783039366415 368 Basel, Switzerland open access |
| spellingShingle | osseointegration dental implant peri-implantitis ligature-induced peri-implantitis aseptic loosening systematic review immune system biomaterials foreign body reaction in vivo study oral implants marginal bone loss immunomodulation mechanotransduction Crestal bone loss osseosufficiency osseoseparation photoacoustic ultrasound brain–bone axis overloading radiography CBCT (cone beam computerized tomography) osteogenesis osteotomy bone healing bone chips drilling tool design fused deposition modeling polyether ether ketone biocomposite orthopedic implant oral implant mechanical properties wettability topography biocompatibility cell adhesion peri-implant endosseous healing dental implantation alveolar bone loss alveolar bone remodeling/regeneration bone biology finite element analysis (FEA) biomechanics cell plasticity dental implants electron microscopy scanning transmission electron microscopy bone-implant interface bone loss overdenture implant survival implant surface soft tissue split-mouth design oral health-related quality of life patient-reported outcome measures biomaterial bone immune implant healing titanium PEEK Cu micro-RNA microarray predictive biomarker epigenomics mucositis diagnosis over-treatment iatrogenic damage abutment height subcrestal implants implant insertion depth vertical mucosal thickness biological width implant installation anchorage technique histology intraosseous temperature finite element model ligature induced peri-implantitis arthroplasty replacement hip hypersensitivity contact allergy and immunology cytokines Interleukin-8 surface properties materials testing implant contamination scanning electron microscopy energy-dispersive X-ray spectrometry convergence clinical study biofilm infection perio-prosthetic joint infection periimplantitis electrolytic cleaning n/a zirconia insertion bone–implant interface heat bone damage early loss augmentation air flow re-osseointegration classification of bone defects dog study thema EDItEUR::M Medicine and Nursing Osseointegrated Oral implants |
| title | Osseointegrated Oral implants |
| title_full | Osseointegrated Oral implants |
| title_fullStr | Osseointegrated Oral implants |
| title_full_unstemmed | Osseointegrated Oral implants |
| title_short | Osseointegrated Oral implants |
| title_sort | osseointegrated oral implants |
| topic | osseointegration dental implant peri-implantitis ligature-induced peri-implantitis aseptic loosening systematic review immune system biomaterials foreign body reaction in vivo study oral implants marginal bone loss immunomodulation mechanotransduction Crestal bone loss osseosufficiency osseoseparation photoacoustic ultrasound brain–bone axis overloading radiography CBCT (cone beam computerized tomography) osteogenesis osteotomy bone healing bone chips drilling tool design fused deposition modeling polyether ether ketone biocomposite orthopedic implant oral implant mechanical properties wettability topography biocompatibility cell adhesion peri-implant endosseous healing dental implantation alveolar bone loss alveolar bone remodeling/regeneration bone biology finite element analysis (FEA) biomechanics cell plasticity dental implants electron microscopy scanning transmission electron microscopy bone-implant interface bone loss overdenture implant survival implant surface soft tissue split-mouth design oral health-related quality of life patient-reported outcome measures biomaterial bone immune implant healing titanium PEEK Cu micro-RNA microarray predictive biomarker epigenomics mucositis diagnosis over-treatment iatrogenic damage abutment height subcrestal implants implant insertion depth vertical mucosal thickness biological width implant installation anchorage technique histology intraosseous temperature finite element model ligature induced peri-implantitis arthroplasty replacement hip hypersensitivity contact allergy and immunology cytokines Interleukin-8 surface properties materials testing implant contamination scanning electron microscopy energy-dispersive X-ray spectrometry convergence clinical study biofilm infection perio-prosthetic joint infection periimplantitis electrolytic cleaning n/a zirconia insertion bone–implant interface heat bone damage early loss augmentation air flow re-osseointegration classification of bone defects dog study thema EDItEUR::M Medicine and Nursing |
| topic_facet | osseointegration dental implant peri-implantitis ligature-induced peri-implantitis aseptic loosening systematic review immune system biomaterials foreign body reaction in vivo study oral implants marginal bone loss immunomodulation mechanotransduction Crestal bone loss osseosufficiency osseoseparation photoacoustic ultrasound brain–bone axis overloading radiography CBCT (cone beam computerized tomography) osteogenesis osteotomy bone healing bone chips drilling tool design fused deposition modeling polyether ether ketone biocomposite orthopedic implant oral implant mechanical properties wettability topography biocompatibility cell adhesion peri-implant endosseous healing dental implantation alveolar bone loss alveolar bone remodeling/regeneration bone biology finite element analysis (FEA) biomechanics cell plasticity dental implants electron microscopy scanning transmission electron microscopy bone-implant interface bone loss overdenture implant survival implant surface soft tissue split-mouth design oral health-related quality of life patient-reported outcome measures biomaterial bone immune implant healing titanium PEEK Cu micro-RNA microarray predictive biomarker epigenomics mucositis diagnosis over-treatment iatrogenic damage abutment height subcrestal implants implant insertion depth vertical mucosal thickness biological width implant installation anchorage technique histology intraosseous temperature finite element model ligature induced peri-implantitis arthroplasty replacement hip hypersensitivity contact allergy and immunology cytokines Interleukin-8 surface properties materials testing implant contamination scanning electron microscopy energy-dispersive X-ray spectrometry convergence clinical study biofilm infection perio-prosthetic joint infection periimplantitis electrolytic cleaning n/a zirconia insertion bone–implant interface heat bone damage early loss augmentation air flow re-osseointegration classification of bone defects dog study thema EDItEUR::M Medicine and Nursing |
| url | ONIX_20210501_9783039366408_931 |