Role of Natural Bioactive Compounds in the Rise and Fall of Cancers

Recent years have seen the idea of a close association between nutrition and the modulation of cancer development/progression reinforced. An increasing amount of experimental and epidemiological evidence has been produced supporting the concept that many different bioactive components of food (e.g....

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প্রকাশিত: MDPI - Multidisciplinary Digital Publishing Institute 2021
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অনলাইন ব্যবহার করুন:ONIX_20210501_9783039432547_943
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collection Directory of Open Access Books
description Recent years have seen the idea of a close association between nutrition and the modulation of cancer development/progression reinforced. An increasing amount of experimental and epidemiological evidence has been produced supporting the concept that many different bioactive components of food (e.g. polyphenols, mono- and polyunsaturated fatty acids, methyl-group donors, etc.) may be implicated in either the promotion of or the protection against carcinogenesis. At the cellular level, such compounds can have an impact on different but sometimes intertwined processes, such as growth and differentiation, DNA repair, programmed cell death, and oxidative stress. In addition, compelling evidence is starting to build up of the existence of primary epigenetic targets of dietary compounds, such as oncogenic/oncosuppressor miRNAs or DNA-modifying enzymes, which in turn impair gene expression and function. Since there is a growing interest in the study of the biochemical and molecular role played by food components and its impact on cellular processes and/or gene expressions directed towards the fine-tuning of cancer phenotypes, in this Special Issue researchers contributed with either research or review articles presenting the latest findings on the intracellular pathways and mechanisms affected by natural bioactive dietary molecules.
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publishDate 2021
publishDateRange 2021
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publisher MDPI - Multidisciplinary Digital Publishing Institute
publisherStr MDPI - Multidisciplinary Digital Publishing Institute
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spelling doab-20.500.12854ir-691972024-03-28T03:33:33Z Role of Natural Bioactive Compounds in the Rise and Fall of Cancers Luparello, Claudio thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Recent years have seen the idea of a close association between nutrition and the modulation of cancer development/progression reinforced. An increasing amount of experimental and epidemiological evidence has been produced supporting the concept that many different bioactive components of food (e.g. polyphenols, mono- and polyunsaturated fatty acids, methyl-group donors, etc.) may be implicated in either the promotion of or the protection against carcinogenesis. At the cellular level, such compounds can have an impact on different but sometimes intertwined processes, such as growth and differentiation, DNA repair, programmed cell death, and oxidative stress. In addition, compelling evidence is starting to build up of the existence of primary epigenetic targets of dietary compounds, such as oncogenic/oncosuppressor miRNAs or DNA-modifying enzymes, which in turn impair gene expression and function. Since there is a growing interest in the study of the biochemical and molecular role played by food components and its impact on cellular processes and/or gene expressions directed towards the fine-tuning of cancer phenotypes, in this Special Issue researchers contributed with either research or review articles presenting the latest findings on the intracellular pathways and mechanisms affected by natural bioactive dietary molecules. 2021-05-01T15:43:32Z 2021-05-01T15:43:32Z 2020 book ONIX_20210501_9783039432547_943 9783039432547 9783039432554 https://directory.doabooks.org/handle/20.500.12854/69197 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/2969 https://mdpi.com/books/pdfview/book/2969 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03943-255-4 10.3390/books978-3-03943-255-4 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783039432547 9783039432554 402 Basel, Switzerland open access
spellingShingle thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
Role of Natural Bioactive Compounds in the Rise and Fall of Cancers
title Role of Natural Bioactive Compounds in the Rise and Fall of Cancers
title_full Role of Natural Bioactive Compounds in the Rise and Fall of Cancers
title_fullStr Role of Natural Bioactive Compounds in the Rise and Fall of Cancers
title_full_unstemmed Role of Natural Bioactive Compounds in the Rise and Fall of Cancers
title_short Role of Natural Bioactive Compounds in the Rise and Fall of Cancers
title_sort role of natural bioactive compounds in the rise and fall of cancers
topic thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
topic_facet thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
url ONIX_20210501_9783039432547_943