Modulators of Oxidative Stress
The book starts with the editors’ preface summarizing the contributions of each of the following thirteen articles dealing with chemical and pharmacological aspects of the molecular modulators of the oxidative stress in regard to various therapeutic approaches in cardiovascular and neurodegenerative...
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| Format: | Online |
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| Language: | English |
| Published: |
MDPI - Multidisciplinary Digital Publishing Institute
2021
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| Online Access: | ONIX_20210501_9783039432288_997 |
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| _version_ | 1869523767038836736 |
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| collection | Directory of Open Access Books |
| description | The book starts with the editors’ preface summarizing the contributions of each of the following thirteen articles dealing with chemical and pharmacological aspects of the molecular modulators of the oxidative stress in regard to various therapeutic approaches in cardiovascular and neurodegenerative diseases, cancer, and diabetes. The seven articles present data from original research studies enlightening the roles and mechanisms of action of small molecular weight compounds (natural and synthetic; ascorbic acid/vitamin C, deferoxamine, N-acetylcysteine, MitoVitE, α-tocopherol, trolox, and ezetimibe) or proteins (SIRT3) in modulation of oxidative stress. In the six review papers, the authors present and discuss the possible therapeutic potential of novel approaches and compounds that are promising and deserve further investigation, in modulation of oxidative stress. |
| format | Online |
| id | doab-20.500.12854ir-69251 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-692512024-03-28T03:33:40Z Modulators of Oxidative Stress Saso, Luciano Gurer-Orhan, Hande Stepanić, Višnja ascorbic acid deferoxamine N-acetylcysteine ischemia/reperfusion cardiac fibroblasts reactive oxygen species photobiomodulation reactive oxygen species (ROS) nuclear factor kappa-light-chain-enhancer of activated B cells (NF-кB) cancer diabetes wound healing glucose pentose phosphate pathway NADPH redox balance glycogen glycolysis stress resistance insulin resistance immunomodulation inflammation olive tree oxidative stress secoirioids sirtuin 3 high fat diet sex differences mice metabolic stress antioxidants ADHD Nrf2 NRF2-KEAP1 ROS cancer metabolism antioxidant cancer therapy chemoresistance radioresistance sepsis MitoVitE mitochondria gene expression cytokines mRNA vitamin C folic acid one-carbon metabolism C2C12 cells metabolomics mass spectrometry type 2 diabetes dipeptidyl peptidase-4 inhibitors biomarkers ER stress Ezetimibe ischemia-reperfusion ionizing radiation liver hydroperoxide epigenetics miR7/MAFG/Nrf2 axe n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences The book starts with the editors’ preface summarizing the contributions of each of the following thirteen articles dealing with chemical and pharmacological aspects of the molecular modulators of the oxidative stress in regard to various therapeutic approaches in cardiovascular and neurodegenerative diseases, cancer, and diabetes. The seven articles present data from original research studies enlightening the roles and mechanisms of action of small molecular weight compounds (natural and synthetic; ascorbic acid/vitamin C, deferoxamine, N-acetylcysteine, MitoVitE, α-tocopherol, trolox, and ezetimibe) or proteins (SIRT3) in modulation of oxidative stress. In the six review papers, the authors present and discuss the possible therapeutic potential of novel approaches and compounds that are promising and deserve further investigation, in modulation of oxidative stress. 2021-05-01T15:44:45Z 2021-05-01T15:44:45Z 2020 book ONIX_20210501_9783039432288_997 9783039432288 9783039432295 https://directory.doabooks.org/handle/20.500.12854/69251 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/3038 https://mdpi.com/books/pdfview/book/3038 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03943-229-5 10.3390/books978-3-03943-229-5 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783039432288 9783039432295 298 Basel, Switzerland open access |
| spellingShingle | ascorbic acid deferoxamine N-acetylcysteine ischemia/reperfusion cardiac fibroblasts reactive oxygen species photobiomodulation reactive oxygen species (ROS) nuclear factor kappa-light-chain-enhancer of activated B cells (NF-кB) cancer diabetes wound healing glucose pentose phosphate pathway NADPH redox balance glycogen glycolysis stress resistance insulin resistance immunomodulation inflammation olive tree oxidative stress secoirioids sirtuin 3 high fat diet sex differences mice metabolic stress antioxidants ADHD Nrf2 NRF2-KEAP1 ROS cancer metabolism antioxidant cancer therapy chemoresistance radioresistance sepsis MitoVitE mitochondria gene expression cytokines mRNA vitamin C folic acid one-carbon metabolism C2C12 cells metabolomics mass spectrometry type 2 diabetes dipeptidyl peptidase-4 inhibitors biomarkers ER stress Ezetimibe ischemia-reperfusion ionizing radiation liver hydroperoxide epigenetics miR7/MAFG/Nrf2 axe n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Modulators of Oxidative Stress |
| title | Modulators of Oxidative Stress |
| title_full | Modulators of Oxidative Stress |
| title_fullStr | Modulators of Oxidative Stress |
| title_full_unstemmed | Modulators of Oxidative Stress |
| title_short | Modulators of Oxidative Stress |
| title_sort | modulators of oxidative stress |
| topic | ascorbic acid deferoxamine N-acetylcysteine ischemia/reperfusion cardiac fibroblasts reactive oxygen species photobiomodulation reactive oxygen species (ROS) nuclear factor kappa-light-chain-enhancer of activated B cells (NF-кB) cancer diabetes wound healing glucose pentose phosphate pathway NADPH redox balance glycogen glycolysis stress resistance insulin resistance immunomodulation inflammation olive tree oxidative stress secoirioids sirtuin 3 high fat diet sex differences mice metabolic stress antioxidants ADHD Nrf2 NRF2-KEAP1 ROS cancer metabolism antioxidant cancer therapy chemoresistance radioresistance sepsis MitoVitE mitochondria gene expression cytokines mRNA vitamin C folic acid one-carbon metabolism C2C12 cells metabolomics mass spectrometry type 2 diabetes dipeptidyl peptidase-4 inhibitors biomarkers ER stress Ezetimibe ischemia-reperfusion ionizing radiation liver hydroperoxide epigenetics miR7/MAFG/Nrf2 axe n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| topic_facet | ascorbic acid deferoxamine N-acetylcysteine ischemia/reperfusion cardiac fibroblasts reactive oxygen species photobiomodulation reactive oxygen species (ROS) nuclear factor kappa-light-chain-enhancer of activated B cells (NF-кB) cancer diabetes wound healing glucose pentose phosphate pathway NADPH redox balance glycogen glycolysis stress resistance insulin resistance immunomodulation inflammation olive tree oxidative stress secoirioids sirtuin 3 high fat diet sex differences mice metabolic stress antioxidants ADHD Nrf2 NRF2-KEAP1 ROS cancer metabolism antioxidant cancer therapy chemoresistance radioresistance sepsis MitoVitE mitochondria gene expression cytokines mRNA vitamin C folic acid one-carbon metabolism C2C12 cells metabolomics mass spectrometry type 2 diabetes dipeptidyl peptidase-4 inhibitors biomarkers ER stress Ezetimibe ischemia-reperfusion ionizing radiation liver hydroperoxide epigenetics miR7/MAFG/Nrf2 axe n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| url | ONIX_20210501_9783039432288_997 |