Botulinum Neurotoxins and Nervous System
This book collects 25 scientific articles from laboratories around the world, all of which use botulinum neurotoxins as the main protagonists of their studies. The use of botulinum neurotoxin in medicine, following its ability to inhibit the effects of various disorders of different etiology on the...
שמור ב:
| פורמט: | Online |
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| שפה: | אנגלית |
| יצא לאור: |
MDPI - Multidisciplinary Digital Publishing Institute
2021
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| נושאים: | |
| גישה מקוונת: | ONIX_20210501_9783039434565_1011 |
| תגים: |
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!
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| _version_ | 1869518796670107648 |
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| collection | Directory of Open Access Books |
| description | This book collects 25 scientific articles from laboratories around the world, all of which use botulinum neurotoxins as the main protagonists of their studies. The use of botulinum neurotoxin in medicine, following its ability to inhibit the effects of various disorders of different etiology on the human organism, constitutes the main topic of each article presented here. This book, which is aimed at both students and medical professionals, attempts to summarize current knowledge about the use of botulinum toxin as a therapeutic agent in many diseases, ranging from spasticity to tremor, form motor dysfunction after stroke to neuropathic pain, from hyperactive muscle to migraine, and so on. Thanks to its simplified writing, accessible to an audience who may not be familiar with the mysteries of science, readers will get new insights into this biological toxin and its multiple applications, not simply relegated to its historical use to correct of face wrinkles. Both review and research articles are presented, not only concerning animal studies, but also clinical reports. This book will provide an up-to-date picture of the state-of-the-art of the possible development of novel applications of botulinum neurotoxins for future therapeutic purposes. |
| format | Online |
| id | doab-20.500.12854ir-69265 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-692652024-03-30T23:22:23Z Botulinum Neurotoxins and Nervous System Luvisetto, Siro botulinum toxin limb tremors muscle selection biological effect various cell types neurotransmitter dermatology novel indication botulinum neurotoxin masticatory system maxillofacial bone dental occlusion orthognathic surgery sialorrhoea drooling salivary glands swallowing eccrine glands onabotulinumtoxin A incobotulinumtoxin A botulinum neurotoxins botulinum neurotoxin serotype A heavy chain botulinum neurotoxin serotype a heavy chain (BoNT/A HC) spinal cord injury (SCI) nerve regeneration growth associated protein 43 (GAP-43) superior cervical ganglion 10 (SCG10) neuronal processes neural regeneration Schwann cells glia spinal cord immunohistochemistry allodynia weight bearing sciatic static index walking track analysis itch SNARE VAMP mast cells compound 48/80 chloroquine spasticity botulinum toxin type A appropriate treatment Therapeutic Index pruritus antipruritic clinical experimental BoNT/A astroglia interleukins microglia TLR2 TLR4 Snap-23 pain cerebral palsy botulinum toxin A complex regional pain syndrome lumbar sympathetic ganglion block chronic pelvic pain overactive detrusor vaginism temporomandibular joint dislocation lateral pterygoid muscle botulinum toxin therapy synaptic transmission SNAP-25 epilepsy Parkinson’s disease neurotransmission blockade electrical activity prion disease new indications formulation delivery refractory chronic migraine tension headache medication overuse headache prophylactic treatment XEOMIN® BTX central neuropathic pain spinal cord injury post-stroke shoulder pain mouse test Clostridium tetani botulinum antitoxin food safety abobotulinumtoxinA upper limb spasticity post-stroke early use ONTIME clinical trial human urodynamics botulinum neurotoxin-A basal ganglia interspecies differences in motor behavior mouse rat interneurons hand tremor treatment electromyography kinematics essential tremor dystonic tremor tremor movement disorders Botulinum toxin upper limb biomechanics joint biomechanics diagnostic guidance clinical decision support spastic paresis electrical stimulation stroke management rehabilitation hand n/a thema EDItEUR::M Medicine and Nursing This book collects 25 scientific articles from laboratories around the world, all of which use botulinum neurotoxins as the main protagonists of their studies. The use of botulinum neurotoxin in medicine, following its ability to inhibit the effects of various disorders of different etiology on the human organism, constitutes the main topic of each article presented here. This book, which is aimed at both students and medical professionals, attempts to summarize current knowledge about the use of botulinum toxin as a therapeutic agent in many diseases, ranging from spasticity to tremor, form motor dysfunction after stroke to neuropathic pain, from hyperactive muscle to migraine, and so on. Thanks to its simplified writing, accessible to an audience who may not be familiar with the mysteries of science, readers will get new insights into this biological toxin and its multiple applications, not simply relegated to its historical use to correct of face wrinkles. Both review and research articles are presented, not only concerning animal studies, but also clinical reports. This book will provide an up-to-date picture of the state-of-the-art of the possible development of novel applications of botulinum neurotoxins for future therapeutic purposes. 2021-05-01T15:45:20Z 2021-05-01T15:45:20Z 2020 book ONIX_20210501_9783039434565_1011 9783039434565 9783039434572 https://directory.doabooks.org/handle/20.500.12854/69265 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/3054 https://mdpi.com/books/pdfview/book/3054 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03943-457-2 10.3390/books978-3-03943-457-2 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783039434565 9783039434572 368 Basel, Switzerland open access |
| spellingShingle | botulinum toxin limb tremors muscle selection biological effect various cell types neurotransmitter dermatology novel indication botulinum neurotoxin masticatory system maxillofacial bone dental occlusion orthognathic surgery sialorrhoea drooling salivary glands swallowing eccrine glands onabotulinumtoxin A incobotulinumtoxin A botulinum neurotoxins botulinum neurotoxin serotype A heavy chain botulinum neurotoxin serotype a heavy chain (BoNT/A HC) spinal cord injury (SCI) nerve regeneration growth associated protein 43 (GAP-43) superior cervical ganglion 10 (SCG10) neuronal processes neural regeneration Schwann cells glia spinal cord immunohistochemistry allodynia weight bearing sciatic static index walking track analysis itch SNARE VAMP mast cells compound 48/80 chloroquine spasticity botulinum toxin type A appropriate treatment Therapeutic Index pruritus antipruritic clinical experimental BoNT/A astroglia interleukins microglia TLR2 TLR4 Snap-23 pain cerebral palsy botulinum toxin A complex regional pain syndrome lumbar sympathetic ganglion block chronic pelvic pain overactive detrusor vaginism temporomandibular joint dislocation lateral pterygoid muscle botulinum toxin therapy synaptic transmission SNAP-25 epilepsy Parkinson’s disease neurotransmission blockade electrical activity prion disease new indications formulation delivery refractory chronic migraine tension headache medication overuse headache prophylactic treatment XEOMIN® BTX central neuropathic pain spinal cord injury post-stroke shoulder pain mouse test Clostridium tetani botulinum antitoxin food safety abobotulinumtoxinA upper limb spasticity post-stroke early use ONTIME clinical trial human urodynamics botulinum neurotoxin-A basal ganglia interspecies differences in motor behavior mouse rat interneurons hand tremor treatment electromyography kinematics essential tremor dystonic tremor tremor movement disorders Botulinum toxin upper limb biomechanics joint biomechanics diagnostic guidance clinical decision support spastic paresis electrical stimulation stroke management rehabilitation hand n/a thema EDItEUR::M Medicine and Nursing Botulinum Neurotoxins and Nervous System |
| title | Botulinum Neurotoxins and Nervous System |
| title_full | Botulinum Neurotoxins and Nervous System |
| title_fullStr | Botulinum Neurotoxins and Nervous System |
| title_full_unstemmed | Botulinum Neurotoxins and Nervous System |
| title_short | Botulinum Neurotoxins and Nervous System |
| title_sort | botulinum neurotoxins and nervous system |
| topic | botulinum toxin limb tremors muscle selection biological effect various cell types neurotransmitter dermatology novel indication botulinum neurotoxin masticatory system maxillofacial bone dental occlusion orthognathic surgery sialorrhoea drooling salivary glands swallowing eccrine glands onabotulinumtoxin A incobotulinumtoxin A botulinum neurotoxins botulinum neurotoxin serotype A heavy chain botulinum neurotoxin serotype a heavy chain (BoNT/A HC) spinal cord injury (SCI) nerve regeneration growth associated protein 43 (GAP-43) superior cervical ganglion 10 (SCG10) neuronal processes neural regeneration Schwann cells glia spinal cord immunohistochemistry allodynia weight bearing sciatic static index walking track analysis itch SNARE VAMP mast cells compound 48/80 chloroquine spasticity botulinum toxin type A appropriate treatment Therapeutic Index pruritus antipruritic clinical experimental BoNT/A astroglia interleukins microglia TLR2 TLR4 Snap-23 pain cerebral palsy botulinum toxin A complex regional pain syndrome lumbar sympathetic ganglion block chronic pelvic pain overactive detrusor vaginism temporomandibular joint dislocation lateral pterygoid muscle botulinum toxin therapy synaptic transmission SNAP-25 epilepsy Parkinson’s disease neurotransmission blockade electrical activity prion disease new indications formulation delivery refractory chronic migraine tension headache medication overuse headache prophylactic treatment XEOMIN® BTX central neuropathic pain spinal cord injury post-stroke shoulder pain mouse test Clostridium tetani botulinum antitoxin food safety abobotulinumtoxinA upper limb spasticity post-stroke early use ONTIME clinical trial human urodynamics botulinum neurotoxin-A basal ganglia interspecies differences in motor behavior mouse rat interneurons hand tremor treatment electromyography kinematics essential tremor dystonic tremor tremor movement disorders Botulinum toxin upper limb biomechanics joint biomechanics diagnostic guidance clinical decision support spastic paresis electrical stimulation stroke management rehabilitation hand n/a thema EDItEUR::M Medicine and Nursing |
| topic_facet | botulinum toxin limb tremors muscle selection biological effect various cell types neurotransmitter dermatology novel indication botulinum neurotoxin masticatory system maxillofacial bone dental occlusion orthognathic surgery sialorrhoea drooling salivary glands swallowing eccrine glands onabotulinumtoxin A incobotulinumtoxin A botulinum neurotoxins botulinum neurotoxin serotype A heavy chain botulinum neurotoxin serotype a heavy chain (BoNT/A HC) spinal cord injury (SCI) nerve regeneration growth associated protein 43 (GAP-43) superior cervical ganglion 10 (SCG10) neuronal processes neural regeneration Schwann cells glia spinal cord immunohistochemistry allodynia weight bearing sciatic static index walking track analysis itch SNARE VAMP mast cells compound 48/80 chloroquine spasticity botulinum toxin type A appropriate treatment Therapeutic Index pruritus antipruritic clinical experimental BoNT/A astroglia interleukins microglia TLR2 TLR4 Snap-23 pain cerebral palsy botulinum toxin A complex regional pain syndrome lumbar sympathetic ganglion block chronic pelvic pain overactive detrusor vaginism temporomandibular joint dislocation lateral pterygoid muscle botulinum toxin therapy synaptic transmission SNAP-25 epilepsy Parkinson’s disease neurotransmission blockade electrical activity prion disease new indications formulation delivery refractory chronic migraine tension headache medication overuse headache prophylactic treatment XEOMIN® BTX central neuropathic pain spinal cord injury post-stroke shoulder pain mouse test Clostridium tetani botulinum antitoxin food safety abobotulinumtoxinA upper limb spasticity post-stroke early use ONTIME clinical trial human urodynamics botulinum neurotoxin-A basal ganglia interspecies differences in motor behavior mouse rat interneurons hand tremor treatment electromyography kinematics essential tremor dystonic tremor tremor movement disorders Botulinum toxin upper limb biomechanics joint biomechanics diagnostic guidance clinical decision support spastic paresis electrical stimulation stroke management rehabilitation hand n/a thema EDItEUR::M Medicine and Nursing |
| url | ONIX_20210501_9783039434565_1011 |