Immunophenotyping in Autoimmune Diseases and Cancer
The cooperation of highly specialized cell types maintains the homeostasis of multicellular organisms. The disturbance of that harmony contributes to the development of several diseases. Most of the cellular functions are executed by proteins, so it is essential to investigate biological processes a...
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| Format: | Online |
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| Langue: | anglais |
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MDPI - Multidisciplinary Digital Publishing Institute
2021
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| Accès en ligne: | ONIX_20210501_9783039434664_1107 |
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| _version_ | 1869520528374497280 |
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| collection | Directory of Open Access Books |
| description | The cooperation of highly specialized cell types maintains the homeostasis of multicellular organisms. The disturbance of that harmony contributes to the development of several diseases. Most of the cellular functions are executed by proteins, so it is essential to investigate biological processes at the protein level. Antibodies, complex biomolecules with high specificity, are used to recognize our protein of interest in a process known as “immunophenotyping”. One of the routinely used methods to study cellular proteins is flow cytometry, which detects cell surface or intracellular proteins at single-cell resolution. The other most frequent technique is the traditional immunohistochemical investigation of microscopic sections of human tissues. We called authors to publish their latest data studying cancer or autoimmune diseases by immunophenotyping. |
| format | Online |
| id | doab-20.500.12854ir-69361 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-693612024-03-30T23:22:41Z Immunophenotyping in Autoimmune Diseases and Cancer Szebeni, Gábor J. Puskás, László G. CD8+CD28− T cells cancer immunology glioblastoma immunotherapy malignant glioma cancer accidental cell death oncosis DDR parthanatos flow cytometry systemic lupus erythematosus T cells glycosylation sialylation lectin binding glycosylation enzymes galectin 1 choriocarcinoma hydatidiform mole galectin gestational trophoblastic disease placental-specific gene systems biology trophoblast differentiation B cells non-switched B cells systemic sclerosis dcSSc TLR CD180 RP105 CpG IL-6 IL-10 natural autoantibodies IgM citrate synthase DNA topoisomerase I unfolded protein response Inositol-requiring enzyme 1 (IRE1) PKR-like endoplasmic reticulum kinase (PERK) Glucose-regulated protein 78 (GRP78) Activating transcription factor 6 (ATF6) immune cells T cell macrophage tumor microenvironment single cell mass cytometry metastatic breast cancer myeloid-derived suppressor cells immunophenotyping breast cancer trastuzumab chimeric antigen receptor cell therapy neuroendocrine neoplasia neuroendocrine tumor neuroendocrine carcinoma immunohistochemistry syntaxin 1 thema EDItEUR::M Medicine and Nursing The cooperation of highly specialized cell types maintains the homeostasis of multicellular organisms. The disturbance of that harmony contributes to the development of several diseases. Most of the cellular functions are executed by proteins, so it is essential to investigate biological processes at the protein level. Antibodies, complex biomolecules with high specificity, are used to recognize our protein of interest in a process known as “immunophenotyping”. One of the routinely used methods to study cellular proteins is flow cytometry, which detects cell surface or intracellular proteins at single-cell resolution. The other most frequent technique is the traditional immunohistochemical investigation of microscopic sections of human tissues. We called authors to publish their latest data studying cancer or autoimmune diseases by immunophenotyping. 2021-05-01T15:47:51Z 2021-05-01T15:47:51Z 2020 book ONIX_20210501_9783039434664_1107 9783039434664 9783039434671 https://directory.doabooks.org/handle/20.500.12854/69361 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/3154 https://mdpi.com/books/pdfview/book/3154 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03943-467-1 10.3390/books978-3-03943-467-1 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783039434664 9783039434671 170 Basel, Switzerland open access |
| spellingShingle | CD8+CD28− T cells cancer immunology glioblastoma immunotherapy malignant glioma cancer accidental cell death oncosis DDR parthanatos flow cytometry systemic lupus erythematosus T cells glycosylation sialylation lectin binding glycosylation enzymes galectin 1 choriocarcinoma hydatidiform mole galectin gestational trophoblastic disease placental-specific gene systems biology trophoblast differentiation B cells non-switched B cells systemic sclerosis dcSSc TLR CD180 RP105 CpG IL-6 IL-10 natural autoantibodies IgM citrate synthase DNA topoisomerase I unfolded protein response Inositol-requiring enzyme 1 (IRE1) PKR-like endoplasmic reticulum kinase (PERK) Glucose-regulated protein 78 (GRP78) Activating transcription factor 6 (ATF6) immune cells T cell macrophage tumor microenvironment single cell mass cytometry metastatic breast cancer myeloid-derived suppressor cells immunophenotyping breast cancer trastuzumab chimeric antigen receptor cell therapy neuroendocrine neoplasia neuroendocrine tumor neuroendocrine carcinoma immunohistochemistry syntaxin 1 thema EDItEUR::M Medicine and Nursing Immunophenotyping in Autoimmune Diseases and Cancer |
| title | Immunophenotyping in Autoimmune Diseases and Cancer |
| title_full | Immunophenotyping in Autoimmune Diseases and Cancer |
| title_fullStr | Immunophenotyping in Autoimmune Diseases and Cancer |
| title_full_unstemmed | Immunophenotyping in Autoimmune Diseases and Cancer |
| title_short | Immunophenotyping in Autoimmune Diseases and Cancer |
| title_sort | immunophenotyping in autoimmune diseases and cancer |
| topic | CD8+CD28− T cells cancer immunology glioblastoma immunotherapy malignant glioma cancer accidental cell death oncosis DDR parthanatos flow cytometry systemic lupus erythematosus T cells glycosylation sialylation lectin binding glycosylation enzymes galectin 1 choriocarcinoma hydatidiform mole galectin gestational trophoblastic disease placental-specific gene systems biology trophoblast differentiation B cells non-switched B cells systemic sclerosis dcSSc TLR CD180 RP105 CpG IL-6 IL-10 natural autoantibodies IgM citrate synthase DNA topoisomerase I unfolded protein response Inositol-requiring enzyme 1 (IRE1) PKR-like endoplasmic reticulum kinase (PERK) Glucose-regulated protein 78 (GRP78) Activating transcription factor 6 (ATF6) immune cells T cell macrophage tumor microenvironment single cell mass cytometry metastatic breast cancer myeloid-derived suppressor cells immunophenotyping breast cancer trastuzumab chimeric antigen receptor cell therapy neuroendocrine neoplasia neuroendocrine tumor neuroendocrine carcinoma immunohistochemistry syntaxin 1 thema EDItEUR::M Medicine and Nursing |
| topic_facet | CD8+CD28− T cells cancer immunology glioblastoma immunotherapy malignant glioma cancer accidental cell death oncosis DDR parthanatos flow cytometry systemic lupus erythematosus T cells glycosylation sialylation lectin binding glycosylation enzymes galectin 1 choriocarcinoma hydatidiform mole galectin gestational trophoblastic disease placental-specific gene systems biology trophoblast differentiation B cells non-switched B cells systemic sclerosis dcSSc TLR CD180 RP105 CpG IL-6 IL-10 natural autoantibodies IgM citrate synthase DNA topoisomerase I unfolded protein response Inositol-requiring enzyme 1 (IRE1) PKR-like endoplasmic reticulum kinase (PERK) Glucose-regulated protein 78 (GRP78) Activating transcription factor 6 (ATF6) immune cells T cell macrophage tumor microenvironment single cell mass cytometry metastatic breast cancer myeloid-derived suppressor cells immunophenotyping breast cancer trastuzumab chimeric antigen receptor cell therapy neuroendocrine neoplasia neuroendocrine tumor neuroendocrine carcinoma immunohistochemistry syntaxin 1 thema EDItEUR::M Medicine and Nursing |
| url | ONIX_20210501_9783039434664_1107 |