Radiopharmaceuticals for PET Imaging - Issue A
Positron emission tomography (PET) is a very useful technique for medical diagnosis and drug development. Radiopharmaceuticals are a key element in PET techniques and one of the pivotal factors influencing the applications of PET. The aim of this Special Issue of Molecules is to report on the recent...
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| Jezik: | engleski |
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MDPI - Multidisciplinary Digital Publishing Institute
2021
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| Online pristup: | ONIX_20210501_9783039432424_1108 |
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| collection | Directory of Open Access Books |
| description | Positron emission tomography (PET) is a very useful technique for medical diagnosis and drug development. Radiopharmaceuticals are a key element in PET techniques and one of the pivotal factors influencing the applications of PET. The aim of this Special Issue of Molecules is to report on the recent research work on a number of aspects of PET radiopharmaceuticals and their preclinical and clinical use. More specifically, the content of this Special Issue includes but is not limited to radiolabeling design, radiosynthesis, synthesis techniques, quality control methodologies, GMP production methods, product formulation, in vitro and in vivo preclinical PET evaluations, clinical evaluations, dosimetry, stability study and metabolite analysis, and modeling. |
| format | Online |
| id | doab-20.500.12854ir-69362 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-693622024-03-30T23:22:37Z Radiopharmaceuticals for PET Imaging - Issue A Roivainen, Anne Li, Xiang-Guo kinetic analysis Siglec-9 gallium-68 vascular adhesion protein VAP-1 infection inflammation osteomyelitis animal model Staphylococcus aureus multiple myeloma positron emission tomography/computed tomography radiopharmaceuticals 18F-fluorodeoxyglucose tetrazine ligation PET SPECT indium-11 fluorine-18 positron emission tomography (PET), defluorination isotopic exchange silicon-based fluoride acceptor bioorthogonal chemistry tetrazine inverse electron-demand Diels-Alder ligation opioid naloxone overdose fentanyl carfentanil [11C]carfentanil positron emission tomography receptor occupancy pharmacokinetics [18F]AlF NOTA NODAGA PODS thiol-reactive linker affibody molecule bioconjugation EGFR tumor imaging vulnerable plaque molecular imaging PET imaging nanobody single-domain antibody sub-millimetre resolution AlF-radiolabelling preclinical radiopharmaceutical dosimetry image-based internal dosimetry OLINDA MCT1/MCT4 lactate transporter inhibitor [18F]FACH radiation safety sigma-1 receptor availability orthotopic xenograft of glioblastoma in mouse small animal Positron Emission Tomography/Magnetic Resonance Imaging (PET/MRI) (S)-(−)-[18F]fluspidine imaging-based biomarker SV2A protein PET radiotracers synaptic loss radiochemistry preclinical development clinical outcomes monocarboxylate transporters (MCTs) FACH 18F-labeled analog of FACH α-CCA blood-brain barrier (BBB) positron emission tomography (PET) imaging peptides proteolysis metabolic stability thema EDItEUR::M Medicine and Nursing Positron emission tomography (PET) is a very useful technique for medical diagnosis and drug development. Radiopharmaceuticals are a key element in PET techniques and one of the pivotal factors influencing the applications of PET. The aim of this Special Issue of Molecules is to report on the recent research work on a number of aspects of PET radiopharmaceuticals and their preclinical and clinical use. More specifically, the content of this Special Issue includes but is not limited to radiolabeling design, radiosynthesis, synthesis techniques, quality control methodologies, GMP production methods, product formulation, in vitro and in vivo preclinical PET evaluations, clinical evaluations, dosimetry, stability study and metabolite analysis, and modeling. 2021-05-01T15:47:52Z 2021-05-01T15:47:52Z 2020 book ONIX_20210501_9783039432424_1108 9783039432424 9783039432431 https://directory.doabooks.org/handle/20.500.12854/69362 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/3155 https://mdpi.com/books/pdfview/book/3155 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03943-243-1 10.3390/books978-3-03943-243-1 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783039432424 9783039432431 212 Basel, Switzerland open access |
| spellingShingle | kinetic analysis Siglec-9 gallium-68 vascular adhesion protein VAP-1 infection inflammation osteomyelitis animal model Staphylococcus aureus multiple myeloma positron emission tomography/computed tomography radiopharmaceuticals 18F-fluorodeoxyglucose tetrazine ligation PET SPECT indium-11 fluorine-18 positron emission tomography (PET), defluorination isotopic exchange silicon-based fluoride acceptor bioorthogonal chemistry tetrazine inverse electron-demand Diels-Alder ligation opioid naloxone overdose fentanyl carfentanil [11C]carfentanil positron emission tomography receptor occupancy pharmacokinetics [18F]AlF NOTA NODAGA PODS thiol-reactive linker affibody molecule bioconjugation EGFR tumor imaging vulnerable plaque molecular imaging PET imaging nanobody single-domain antibody sub-millimetre resolution AlF-radiolabelling preclinical radiopharmaceutical dosimetry image-based internal dosimetry OLINDA MCT1/MCT4 lactate transporter inhibitor [18F]FACH radiation safety sigma-1 receptor availability orthotopic xenograft of glioblastoma in mouse small animal Positron Emission Tomography/Magnetic Resonance Imaging (PET/MRI) (S)-(−)-[18F]fluspidine imaging-based biomarker SV2A protein PET radiotracers synaptic loss radiochemistry preclinical development clinical outcomes monocarboxylate transporters (MCTs) FACH 18F-labeled analog of FACH α-CCA blood-brain barrier (BBB) positron emission tomography (PET) imaging peptides proteolysis metabolic stability thema EDItEUR::M Medicine and Nursing Radiopharmaceuticals for PET Imaging - Issue A |
| title | Radiopharmaceuticals for PET Imaging - Issue A |
| title_full | Radiopharmaceuticals for PET Imaging - Issue A |
| title_fullStr | Radiopharmaceuticals for PET Imaging - Issue A |
| title_full_unstemmed | Radiopharmaceuticals for PET Imaging - Issue A |
| title_short | Radiopharmaceuticals for PET Imaging - Issue A |
| title_sort | radiopharmaceuticals for pet imaging issue a |
| topic | kinetic analysis Siglec-9 gallium-68 vascular adhesion protein VAP-1 infection inflammation osteomyelitis animal model Staphylococcus aureus multiple myeloma positron emission tomography/computed tomography radiopharmaceuticals 18F-fluorodeoxyglucose tetrazine ligation PET SPECT indium-11 fluorine-18 positron emission tomography (PET), defluorination isotopic exchange silicon-based fluoride acceptor bioorthogonal chemistry tetrazine inverse electron-demand Diels-Alder ligation opioid naloxone overdose fentanyl carfentanil [11C]carfentanil positron emission tomography receptor occupancy pharmacokinetics [18F]AlF NOTA NODAGA PODS thiol-reactive linker affibody molecule bioconjugation EGFR tumor imaging vulnerable plaque molecular imaging PET imaging nanobody single-domain antibody sub-millimetre resolution AlF-radiolabelling preclinical radiopharmaceutical dosimetry image-based internal dosimetry OLINDA MCT1/MCT4 lactate transporter inhibitor [18F]FACH radiation safety sigma-1 receptor availability orthotopic xenograft of glioblastoma in mouse small animal Positron Emission Tomography/Magnetic Resonance Imaging (PET/MRI) (S)-(−)-[18F]fluspidine imaging-based biomarker SV2A protein PET radiotracers synaptic loss radiochemistry preclinical development clinical outcomes monocarboxylate transporters (MCTs) FACH 18F-labeled analog of FACH α-CCA blood-brain barrier (BBB) positron emission tomography (PET) imaging peptides proteolysis metabolic stability thema EDItEUR::M Medicine and Nursing |
| topic_facet | kinetic analysis Siglec-9 gallium-68 vascular adhesion protein VAP-1 infection inflammation osteomyelitis animal model Staphylococcus aureus multiple myeloma positron emission tomography/computed tomography radiopharmaceuticals 18F-fluorodeoxyglucose tetrazine ligation PET SPECT indium-11 fluorine-18 positron emission tomography (PET), defluorination isotopic exchange silicon-based fluoride acceptor bioorthogonal chemistry tetrazine inverse electron-demand Diels-Alder ligation opioid naloxone overdose fentanyl carfentanil [11C]carfentanil positron emission tomography receptor occupancy pharmacokinetics [18F]AlF NOTA NODAGA PODS thiol-reactive linker affibody molecule bioconjugation EGFR tumor imaging vulnerable plaque molecular imaging PET imaging nanobody single-domain antibody sub-millimetre resolution AlF-radiolabelling preclinical radiopharmaceutical dosimetry image-based internal dosimetry OLINDA MCT1/MCT4 lactate transporter inhibitor [18F]FACH radiation safety sigma-1 receptor availability orthotopic xenograft of glioblastoma in mouse small animal Positron Emission Tomography/Magnetic Resonance Imaging (PET/MRI) (S)-(−)-[18F]fluspidine imaging-based biomarker SV2A protein PET radiotracers synaptic loss radiochemistry preclinical development clinical outcomes monocarboxylate transporters (MCTs) FACH 18F-labeled analog of FACH α-CCA blood-brain barrier (BBB) positron emission tomography (PET) imaging peptides proteolysis metabolic stability thema EDItEUR::M Medicine and Nursing |
| url | ONIX_20210501_9783039432424_1108 |