Advances in Cross-Coupling Reactions
In this Special Issue, recent advances in cross-coupling reactions are presented in the form of original research articles, reviews, and short communications. These contributions cover different topics in this area, including novel coupling reactions, reaction conditions, synthetic alternatives, met...
Zapisane w:
| Format: | Online |
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| Język: | angielski |
| Wydane: |
MDPI - Multidisciplinary Digital Publishing Institute
2021
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| Hasła przedmiotowe: | |
| Dostęp online: | ONIX_20210501_9783039435678_1110 |
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| _version_ | 1869526724485578752 |
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| collection | Directory of Open Access Books |
| description | In this Special Issue, recent advances in cross-coupling reactions are presented in the form of original research articles, reviews, and short communications. These contributions cover different topics in this area, including novel coupling reactions, reaction conditions, synthetic alternatives, metal ligands, and applications for new pharmaceutical compounds and organic materials. In particular, the reviews deal with methodologies such as the synthesis of diarylketones through palladium catalysis and the most relevant examples of Suzuki–Miyaura and Buchwald–Hartwig coupling reactions in the synthesis of bioactive compounds. The synthetic utility of cross-coupling reactions for the synthesis of medium-size rings and the utility of Stille and Suzuki coupling reactions for the synthesis of new molecular machines based on sterically hindered anthracenyl trypticenyl units are also summarized. The original research articles present the synthesis of 2-alkynylpyrrols by inverse Sonogashira coupling and the synthesis of indoles under oxidative dearomative cross-dehydrogenative conditions. The efficient combination of iridium-catalyzed C–H borylation of aryl halides with the Sonogashira coupling and a sequential iridium-catalyzed borylation of NH-free pyrroles followed by a Suzuki–Miyaura reaction are included. The synthesis of aryl propionic acids, a common structural motif in medicinal chemistry, and the synthesis of new organic dyes are also covered. |
| format | Online |
| id | doab-20.500.12854ir-69364 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-693642024-03-27T16:34:41Z Advances in Cross-Coupling Reactions Pérez Sestelo, José Sarandeses, Luis A. cross coupling dearomatization C-H functionalization indolin-3-ones dimerization and trimerization of indoles C–H borylation Sonogashira cross-coupling borylated aryl alkynes one-pot reaction restricted rotations M(CO)3 tripods molecular brakes and gears X-ray V-T NMR borylation Suzuki coupling NH-Free 5-aryl pyrrole-2-carboxylates iridium-catalyzed heteroaryl substituted pyrroles 2,3′-bipyrrole electrophilic haloacetylenes pyrroles ethynylpyrroles furans thiophenes pyrazoles Al2O3 transition-metal catalysis intramolecular cyclization medium-sized heterocycles C-H activation acylation palladium arenes heteroarenes indigo dyes DSSC synthesis spectroscopy Heck reaction styrene methoxycarbonylation profene cross-coupling reactions C-C bond forming reactions C-Heteroatom bond forming reactions clinical candidate DNA-encoded libraries cyclopeptides allosteric modulators PROTAC catalysis in water C–C cross-coupling Suzuki–Miyaura reaction sulfonated salan n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general In this Special Issue, recent advances in cross-coupling reactions are presented in the form of original research articles, reviews, and short communications. These contributions cover different topics in this area, including novel coupling reactions, reaction conditions, synthetic alternatives, metal ligands, and applications for new pharmaceutical compounds and organic materials. In particular, the reviews deal with methodologies such as the synthesis of diarylketones through palladium catalysis and the most relevant examples of Suzuki–Miyaura and Buchwald–Hartwig coupling reactions in the synthesis of bioactive compounds. The synthetic utility of cross-coupling reactions for the synthesis of medium-size rings and the utility of Stille and Suzuki coupling reactions for the synthesis of new molecular machines based on sterically hindered anthracenyl trypticenyl units are also summarized. The original research articles present the synthesis of 2-alkynylpyrrols by inverse Sonogashira coupling and the synthesis of indoles under oxidative dearomative cross-dehydrogenative conditions. The efficient combination of iridium-catalyzed C–H borylation of aryl halides with the Sonogashira coupling and a sequential iridium-catalyzed borylation of NH-free pyrroles followed by a Suzuki–Miyaura reaction are included. The synthesis of aryl propionic acids, a common structural motif in medicinal chemistry, and the synthesis of new organic dyes are also covered. 2021-05-01T15:47:55Z 2021-05-01T15:47:55Z 2020 book ONIX_20210501_9783039435678_1110 9783039435678 9783039435685 https://directory.doabooks.org/handle/20.500.12854/69364 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/3157 https://mdpi.com/books/pdfview/book/3157 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03943-568-5 10.3390/books978-3-03943-568-5 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783039435678 9783039435685 234 Basel, Switzerland open access |
| spellingShingle | cross coupling dearomatization C-H functionalization indolin-3-ones dimerization and trimerization of indoles C–H borylation Sonogashira cross-coupling borylated aryl alkynes one-pot reaction restricted rotations M(CO)3 tripods molecular brakes and gears X-ray V-T NMR borylation Suzuki coupling NH-Free 5-aryl pyrrole-2-carboxylates iridium-catalyzed heteroaryl substituted pyrroles 2,3′-bipyrrole electrophilic haloacetylenes pyrroles ethynylpyrroles furans thiophenes pyrazoles Al2O3 transition-metal catalysis intramolecular cyclization medium-sized heterocycles C-H activation acylation palladium arenes heteroarenes indigo dyes DSSC synthesis spectroscopy Heck reaction styrene methoxycarbonylation profene cross-coupling reactions C-C bond forming reactions C-Heteroatom bond forming reactions clinical candidate DNA-encoded libraries cyclopeptides allosteric modulators PROTAC catalysis in water C–C cross-coupling Suzuki–Miyaura reaction sulfonated salan n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general Advances in Cross-Coupling Reactions |
| title | Advances in Cross-Coupling Reactions |
| title_full | Advances in Cross-Coupling Reactions |
| title_fullStr | Advances in Cross-Coupling Reactions |
| title_full_unstemmed | Advances in Cross-Coupling Reactions |
| title_short | Advances in Cross-Coupling Reactions |
| title_sort | advances in cross coupling reactions |
| topic | cross coupling dearomatization C-H functionalization indolin-3-ones dimerization and trimerization of indoles C–H borylation Sonogashira cross-coupling borylated aryl alkynes one-pot reaction restricted rotations M(CO)3 tripods molecular brakes and gears X-ray V-T NMR borylation Suzuki coupling NH-Free 5-aryl pyrrole-2-carboxylates iridium-catalyzed heteroaryl substituted pyrroles 2,3′-bipyrrole electrophilic haloacetylenes pyrroles ethynylpyrroles furans thiophenes pyrazoles Al2O3 transition-metal catalysis intramolecular cyclization medium-sized heterocycles C-H activation acylation palladium arenes heteroarenes indigo dyes DSSC synthesis spectroscopy Heck reaction styrene methoxycarbonylation profene cross-coupling reactions C-C bond forming reactions C-Heteroatom bond forming reactions clinical candidate DNA-encoded libraries cyclopeptides allosteric modulators PROTAC catalysis in water C–C cross-coupling Suzuki–Miyaura reaction sulfonated salan n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general |
| topic_facet | cross coupling dearomatization C-H functionalization indolin-3-ones dimerization and trimerization of indoles C–H borylation Sonogashira cross-coupling borylated aryl alkynes one-pot reaction restricted rotations M(CO)3 tripods molecular brakes and gears X-ray V-T NMR borylation Suzuki coupling NH-Free 5-aryl pyrrole-2-carboxylates iridium-catalyzed heteroaryl substituted pyrroles 2,3′-bipyrrole electrophilic haloacetylenes pyrroles ethynylpyrroles furans thiophenes pyrazoles Al2O3 transition-metal catalysis intramolecular cyclization medium-sized heterocycles C-H activation acylation palladium arenes heteroarenes indigo dyes DSSC synthesis spectroscopy Heck reaction styrene methoxycarbonylation profene cross-coupling reactions C-C bond forming reactions C-Heteroatom bond forming reactions clinical candidate DNA-encoded libraries cyclopeptides allosteric modulators PROTAC catalysis in water C–C cross-coupling Suzuki–Miyaura reaction sulfonated salan n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general |
| url | ONIX_20210501_9783039435678_1110 |