Apheresis in Neurological Disorders
Apheresis refers to an extracorporeal therapy which aims at removing pathological constituents from the patients’ blood. Due to the development of new techniques as well as the discovery of novel autoimmune antibodies, it is increasingly recognized as an important therapeutic option for a variety of...
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| Format: | Online |
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| Sprache: | Englisch |
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MDPI - Multidisciplinary Digital Publishing Institute
2021
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| Online-Zugang: | ONIX_20210501_9783039435852_1113 |
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| collection | Directory of Open Access Books |
| description | Apheresis refers to an extracorporeal therapy which aims at removing pathological constituents from the patients’ blood. Due to the development of new techniques as well as the discovery of novel autoimmune antibodies, it is increasingly recognized as an important therapeutic option for a variety of autoimmune-mediated neurological disorders, including multiple sclerosis, myasthenia gravis, autoimmune encephalitis, Guillain–Barré syndrome, and many others. Therapeutic plasma exchange (TPE) constitutes the standard method of apheresis for most indications, while immunoadsorption (IA) offers a more specific, low-risk alternative. Both methods aim at removing auto-antibodies from the blood. Evidence for most neurological diseases is still low. Interestingly, more recent developments suggest that apheresis is not limited to the removal of autoantibodies but may also be useful in neurodegenerative and possibly even in acute vascular disorders. |
| format | Online |
| id | doab-20.500.12854ir-69367 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-693672024-03-31T13:09:56Z Apheresis in Neurological Disorders Dorst, Johannes immunoadsorption acute relapsing multiple sclerosis plasma exchange therapeutic apheresis multiple sclerosis optic neuritis relapse class IV steroids Alzheimer’s clinical syndrome dementia autoantibodies α1-Adrenergic receptor Inflammatory neuropathy chronic inflammatory demyelinating polyneuropathy Guillain-Barré syndrome paranodal antibodies plasmapheresis Myalgic Encephalomyelitis/Chronic Fatigue Syndrome ß2 adrenoreceptor autoantibody autoimmune encephalitis limbic encephalitis NMDAR (N-Methyl-D-Aspartat) antibody paraneoplastic apheresis therapeutic plasma exchange neurological diseases CRP stroke inflammation n/a thema EDItEUR::M Medicine and Nursing Apheresis refers to an extracorporeal therapy which aims at removing pathological constituents from the patients’ blood. Due to the development of new techniques as well as the discovery of novel autoimmune antibodies, it is increasingly recognized as an important therapeutic option for a variety of autoimmune-mediated neurological disorders, including multiple sclerosis, myasthenia gravis, autoimmune encephalitis, Guillain–Barré syndrome, and many others. Therapeutic plasma exchange (TPE) constitutes the standard method of apheresis for most indications, while immunoadsorption (IA) offers a more specific, low-risk alternative. Both methods aim at removing auto-antibodies from the blood. Evidence for most neurological diseases is still low. Interestingly, more recent developments suggest that apheresis is not limited to the removal of autoantibodies but may also be useful in neurodegenerative and possibly even in acute vascular disorders. 2021-05-01T15:48:00Z 2021-05-01T15:48:00Z 2020 book ONIX_20210501_9783039435852_1113 9783039435852 9783039435869 https://directory.doabooks.org/handle/20.500.12854/69367 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/3160 https://mdpi.com/books/pdfview/book/3160 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03943-586-9 10.3390/books978-3-03943-586-9 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783039435852 9783039435869 174 Basel, Switzerland open access |
| spellingShingle | immunoadsorption acute relapsing multiple sclerosis plasma exchange therapeutic apheresis multiple sclerosis optic neuritis relapse class IV steroids Alzheimer’s clinical syndrome dementia autoantibodies α1-Adrenergic receptor Inflammatory neuropathy chronic inflammatory demyelinating polyneuropathy Guillain-Barré syndrome paranodal antibodies plasmapheresis Myalgic Encephalomyelitis/Chronic Fatigue Syndrome ß2 adrenoreceptor autoantibody autoimmune encephalitis limbic encephalitis NMDAR (N-Methyl-D-Aspartat) antibody paraneoplastic apheresis therapeutic plasma exchange neurological diseases CRP stroke inflammation n/a thema EDItEUR::M Medicine and Nursing Apheresis in Neurological Disorders |
| title | Apheresis in Neurological Disorders |
| title_full | Apheresis in Neurological Disorders |
| title_fullStr | Apheresis in Neurological Disorders |
| title_full_unstemmed | Apheresis in Neurological Disorders |
| title_short | Apheresis in Neurological Disorders |
| title_sort | apheresis in neurological disorders |
| topic | immunoadsorption acute relapsing multiple sclerosis plasma exchange therapeutic apheresis multiple sclerosis optic neuritis relapse class IV steroids Alzheimer’s clinical syndrome dementia autoantibodies α1-Adrenergic receptor Inflammatory neuropathy chronic inflammatory demyelinating polyneuropathy Guillain-Barré syndrome paranodal antibodies plasmapheresis Myalgic Encephalomyelitis/Chronic Fatigue Syndrome ß2 adrenoreceptor autoantibody autoimmune encephalitis limbic encephalitis NMDAR (N-Methyl-D-Aspartat) antibody paraneoplastic apheresis therapeutic plasma exchange neurological diseases CRP stroke inflammation n/a thema EDItEUR::M Medicine and Nursing |
| topic_facet | immunoadsorption acute relapsing multiple sclerosis plasma exchange therapeutic apheresis multiple sclerosis optic neuritis relapse class IV steroids Alzheimer’s clinical syndrome dementia autoantibodies α1-Adrenergic receptor Inflammatory neuropathy chronic inflammatory demyelinating polyneuropathy Guillain-Barré syndrome paranodal antibodies plasmapheresis Myalgic Encephalomyelitis/Chronic Fatigue Syndrome ß2 adrenoreceptor autoantibody autoimmune encephalitis limbic encephalitis NMDAR (N-Methyl-D-Aspartat) antibody paraneoplastic apheresis therapeutic plasma exchange neurological diseases CRP stroke inflammation n/a thema EDItEUR::M Medicine and Nursing |
| url | ONIX_20210501_9783039435852_1113 |