Enzyme Inhibitor from Marine Organisms
Marine habitats are promising sources to identify novel organisms and compounds. A total of 70% of the planet’s surface is covered by ocean, and little is known about the biosphere within these habitats. In the last few years, numerous novel bioactive compounds or secondary metabolites from marine e...
محفوظ في:
| التنسيق: | Online |
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| اللغة: | الإنجليزية |
| منشور في: |
MDPI - Multidisciplinary Digital Publishing Institute
2021
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| الموضوعات: | |
| الوصول للمادة أونلاين: | ONIX_20210501_9783039437832_1170 |
| الوسوم: |
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| _version_ | 1869525318954385408 |
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| collection | Directory of Open Access Books |
| description | Marine habitats are promising sources to identify novel organisms and compounds. A total of 70% of the planet’s surface is covered by ocean, and little is known about the biosphere within these habitats. In the last few years, numerous novel bioactive compounds or secondary metabolites from marine environments have been described. This is, and will be, a promising source of candidate compounds in pharma research and chemical biology. In recent years, a number of novel techniques have been introduced to the field and it has become easier to actually (bio-)prospect compounds such as enzyme inhibitors. Those novel compounds then need to be characterized and evaluated in comparison to well-known representatives. This Special Issue focuses on the description of novel enzyme inhibitors of marine origin, including bioprospecting, omic approaches, and structural and mechanistic aspects. |
| format | Online |
| id | doab-20.500.12854ir-69424 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-694242024-03-27T16:34:39Z Enzyme Inhibitor from Marine Organisms Tischler, Dirk sponge Monanchora pulchra pentacyclic guanidine alkaloids GH36 α-galactosidase GH109 α-N-acetylgalactosaminidase slow-binding irreversible inhibitor monanchomycalin B monanhocidin A normonanhocidin A Alzheimer′s disease BACE1 acetylcholinesterase in silico docking phlorotannins Ulva intestinalis ACE inhibitory peptide optimization purification structural identification molecular docking secondary metabolites Mycosphaerella sp. asperchalasine α-glucosidase kinase inhibitors drug development marine natural products inhibitor macroalgae marine fish protease Ulva ohnoi functional annotation structure–function relation natural products bioactives enzyme inhibition inactivation marine bacteria marine fungi marine sponges thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general Marine habitats are promising sources to identify novel organisms and compounds. A total of 70% of the planet’s surface is covered by ocean, and little is known about the biosphere within these habitats. In the last few years, numerous novel bioactive compounds or secondary metabolites from marine environments have been described. This is, and will be, a promising source of candidate compounds in pharma research and chemical biology. In recent years, a number of novel techniques have been introduced to the field and it has become easier to actually (bio-)prospect compounds such as enzyme inhibitors. Those novel compounds then need to be characterized and evaluated in comparison to well-known representatives. This Special Issue focuses on the description of novel enzyme inhibitors of marine origin, including bioprospecting, omic approaches, and structural and mechanistic aspects. 2021-05-01T15:49:19Z 2021-05-01T15:49:19Z 2020 book ONIX_20210501_9783039437832_1170 9783039437832 9783039437849 https://directory.doabooks.org/handle/20.500.12854/69424 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/3226 https://mdpi.com/books/pdfview/book/3226 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03943-784-9 10.3390/books978-3-03943-784-9 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783039437832 9783039437849 130 Basel, Switzerland open access |
| spellingShingle | sponge Monanchora pulchra pentacyclic guanidine alkaloids GH36 α-galactosidase GH109 α-N-acetylgalactosaminidase slow-binding irreversible inhibitor monanchomycalin B monanhocidin A normonanhocidin A Alzheimer′s disease BACE1 acetylcholinesterase in silico docking phlorotannins Ulva intestinalis ACE inhibitory peptide optimization purification structural identification molecular docking secondary metabolites Mycosphaerella sp. asperchalasine α-glucosidase kinase inhibitors drug development marine natural products inhibitor macroalgae marine fish protease Ulva ohnoi functional annotation structure–function relation natural products bioactives enzyme inhibition inactivation marine bacteria marine fungi marine sponges thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general Enzyme Inhibitor from Marine Organisms |
| title | Enzyme Inhibitor from Marine Organisms |
| title_full | Enzyme Inhibitor from Marine Organisms |
| title_fullStr | Enzyme Inhibitor from Marine Organisms |
| title_full_unstemmed | Enzyme Inhibitor from Marine Organisms |
| title_short | Enzyme Inhibitor from Marine Organisms |
| title_sort | enzyme inhibitor from marine organisms |
| topic | sponge Monanchora pulchra pentacyclic guanidine alkaloids GH36 α-galactosidase GH109 α-N-acetylgalactosaminidase slow-binding irreversible inhibitor monanchomycalin B monanhocidin A normonanhocidin A Alzheimer′s disease BACE1 acetylcholinesterase in silico docking phlorotannins Ulva intestinalis ACE inhibitory peptide optimization purification structural identification molecular docking secondary metabolites Mycosphaerella sp. asperchalasine α-glucosidase kinase inhibitors drug development marine natural products inhibitor macroalgae marine fish protease Ulva ohnoi functional annotation structure–function relation natural products bioactives enzyme inhibition inactivation marine bacteria marine fungi marine sponges thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general |
| topic_facet | sponge Monanchora pulchra pentacyclic guanidine alkaloids GH36 α-galactosidase GH109 α-N-acetylgalactosaminidase slow-binding irreversible inhibitor monanchomycalin B monanhocidin A normonanhocidin A Alzheimer′s disease BACE1 acetylcholinesterase in silico docking phlorotannins Ulva intestinalis ACE inhibitory peptide optimization purification structural identification molecular docking secondary metabolites Mycosphaerella sp. asperchalasine α-glucosidase kinase inhibitors drug development marine natural products inhibitor macroalgae marine fish protease Ulva ohnoi functional annotation structure–function relation natural products bioactives enzyme inhibition inactivation marine bacteria marine fungi marine sponges thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general |
| url | ONIX_20210501_9783039437832_1170 |