Biomaterial-Related Infections

The use of medical devices (e.g., catheters, implants, and probes) is a common and essential part of medical care for both diagnostic and therapeutic purposes. However, these devices quite frequently lead to the incidence of infections due to the colonization of their abiotic surfaces by biofilm-gro...

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প্রকাশিত: MDPI - Multidisciplinary Digital Publishing Institute 2021
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অনলাইন ব্যবহার করুন:ONIX_20210501_9783039434381_1184
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collection Directory of Open Access Books
description The use of medical devices (e.g., catheters, implants, and probes) is a common and essential part of medical care for both diagnostic and therapeutic purposes. However, these devices quite frequently lead to the incidence of infections due to the colonization of their abiotic surfaces by biofilm-growing microorganisms, which are progressively resistant to antimicrobial therapies. Several methods based on anti-infective biomaterials that repel microbes have been developed to combat device-related infections. Among these strategies, surface coating with antibiotics (e.g., beta-lactams), natural compounds (e.g., polyphenols), or inorganic elements (e.g., silver and copper nanoparticles) has been widely recognized as exhibiting broad-spectrum bactericidal or bacteriostatic activity. So, in order to achieve a better therapeutic response, it is crucial to understand how these infections are different from others. This will allow us to find new biomaterials characterized by antifouling coatings with repellent properties or low adhesion towards microorganisms, or antimicrobial coatings that are capable of killing microbes approaching the surface, improving biomaterial functionalization strategies and supporting tissues’ bio-integration.
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publisherStr MDPI - Multidisciplinary Digital Publishing Institute
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spelling doab-20.500.12854ir-694382024-03-30T23:22:56Z Biomaterial-Related Infections Rodrigues, Célia F. Martins, Natália Candida biofilms diabetes medical devices candidiasis metabolic disorder hyperglycemia infection Candida glabrata candidemia echinocandins resistance micafungin caspofungin in vivo titanium dioxide nanotubes autoclaving titanium alloy biocompatibility wettability mechanical properties silver nanoparticles titanium dioxide nanotubes silver ions release biointegration antimicrobial activity polyethylene terephthalate PET electrospinning nanofibers antimicrobial agents Taguchi method antimicrobial efficiency cold atmospheric-pressure plasma jet (CAPJ) Escherichia coli DNA double-strand breaks scanning electron microscopy Ti6Al4V implants anodization process XPS genotoxicity assessment anti-inflammatory properties oral biofilm infection control Streptococcus mutans Candida spp. natural compounds antimicrobial resistance n/a thema EDItEUR::M Medicine and Nursing The use of medical devices (e.g., catheters, implants, and probes) is a common and essential part of medical care for both diagnostic and therapeutic purposes. However, these devices quite frequently lead to the incidence of infections due to the colonization of their abiotic surfaces by biofilm-growing microorganisms, which are progressively resistant to antimicrobial therapies. Several methods based on anti-infective biomaterials that repel microbes have been developed to combat device-related infections. Among these strategies, surface coating with antibiotics (e.g., beta-lactams), natural compounds (e.g., polyphenols), or inorganic elements (e.g., silver and copper nanoparticles) has been widely recognized as exhibiting broad-spectrum bactericidal or bacteriostatic activity. So, in order to achieve a better therapeutic response, it is crucial to understand how these infections are different from others. This will allow us to find new biomaterials characterized by antifouling coatings with repellent properties or low adhesion towards microorganisms, or antimicrobial coatings that are capable of killing microbes approaching the surface, improving biomaterial functionalization strategies and supporting tissues’ bio-integration. 2021-05-01T15:49:39Z 2021-05-01T15:49:39Z 2020 book ONIX_20210501_9783039434381_1184 9783039434381 9783039434398 https://directory.doabooks.org/handle/20.500.12854/69438 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/3242 https://mdpi.com/books/pdfview/book/3242 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03943-439-8 10.3390/books978-3-03943-439-8 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783039434381 9783039434398 204 Basel, Switzerland open access
spellingShingle Candida
biofilms
diabetes
medical devices
candidiasis
metabolic disorder
hyperglycemia
infection
Candida glabrata
candidemia
echinocandins
resistance
micafungin
caspofungin
in vivo
titanium dioxide
nanotubes
autoclaving
titanium alloy
biocompatibility
wettability
mechanical properties
silver nanoparticles
titanium dioxide nanotubes
silver ions release
biointegration
antimicrobial activity
polyethylene terephthalate
PET
electrospinning
nanofibers
antimicrobial agents
Taguchi method
antimicrobial efficiency
cold atmospheric-pressure plasma jet (CAPJ)
Escherichia coli
DNA double-strand breaks
scanning electron microscopy
Ti6Al4V implants
anodization process
XPS
genotoxicity assessment
anti-inflammatory properties
oral biofilm
infection control
Streptococcus mutans
Candida spp.
natural compounds
antimicrobial resistance
n/a
thema EDItEUR::M Medicine and Nursing
Biomaterial-Related Infections
title Biomaterial-Related Infections
title_full Biomaterial-Related Infections
title_fullStr Biomaterial-Related Infections
title_full_unstemmed Biomaterial-Related Infections
title_short Biomaterial-Related Infections
title_sort biomaterial related infections
topic Candida
biofilms
diabetes
medical devices
candidiasis
metabolic disorder
hyperglycemia
infection
Candida glabrata
candidemia
echinocandins
resistance
micafungin
caspofungin
in vivo
titanium dioxide
nanotubes
autoclaving
titanium alloy
biocompatibility
wettability
mechanical properties
silver nanoparticles
titanium dioxide nanotubes
silver ions release
biointegration
antimicrobial activity
polyethylene terephthalate
PET
electrospinning
nanofibers
antimicrobial agents
Taguchi method
antimicrobial efficiency
cold atmospheric-pressure plasma jet (CAPJ)
Escherichia coli
DNA double-strand breaks
scanning electron microscopy
Ti6Al4V implants
anodization process
XPS
genotoxicity assessment
anti-inflammatory properties
oral biofilm
infection control
Streptococcus mutans
Candida spp.
natural compounds
antimicrobial resistance
n/a
thema EDItEUR::M Medicine and Nursing
topic_facet Candida
biofilms
diabetes
medical devices
candidiasis
metabolic disorder
hyperglycemia
infection
Candida glabrata
candidemia
echinocandins
resistance
micafungin
caspofungin
in vivo
titanium dioxide
nanotubes
autoclaving
titanium alloy
biocompatibility
wettability
mechanical properties
silver nanoparticles
titanium dioxide nanotubes
silver ions release
biointegration
antimicrobial activity
polyethylene terephthalate
PET
electrospinning
nanofibers
antimicrobial agents
Taguchi method
antimicrobial efficiency
cold atmospheric-pressure plasma jet (CAPJ)
Escherichia coli
DNA double-strand breaks
scanning electron microscopy
Ti6Al4V implants
anodization process
XPS
genotoxicity assessment
anti-inflammatory properties
oral biofilm
infection control
Streptococcus mutans
Candida spp.
natural compounds
antimicrobial resistance
n/a
thema EDItEUR::M Medicine and Nursing
url ONIX_20210501_9783039434381_1184