The Advances and Applications of Optogenetics
This book provides an update for the rapidly developing technology known as “optogenetics”, which is the use of genetically encoded light-sensitive molecular elements (usually derived from lower organisms) to control or report various physiological and biochemical processes within the cell. Two ongo...
שמור ב:
| פורמט: | Online |
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| שפה: | אנגלית |
| יצא לאור: |
MDPI - Multidisciplinary Digital Publishing Institute
2021
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| נושאים: | |
| גישה מקוונת: | ONIX_20210501_9783039436736_1193 |
| תגים: |
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| _version_ | 1869522227315081216 |
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| collection | Directory of Open Access Books |
| description | This book provides an update for the rapidly developing technology known as “optogenetics”, which is the use of genetically encoded light-sensitive molecular elements (usually derived from lower organisms) to control or report various physiological and biochemical processes within the cell. Two ongoing clinical trials use optogenetic tools for vision restoration, and optogenetic strategies have been suggested as novel therapies for several neurological, psychiatric and cardiac disorders. This Special Issue comprises two reviews and seven experimental papers on different types of light-sensitive modules widely used in optogenetic studies. These papers demonstrate the efficiency and versatility of optogenetics and are expected to be equally relevant for advanced users and beginners considering using optogenetic tools in their research. |
| format | Online |
| id | doab-20.500.12854ir-69447 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-694472024-03-28T03:33:35Z The Advances and Applications of Optogenetics Govorunova, Elena G. Sineshchekov, Oleg A. optogenetic tools neuroscience calcium sensor voltage sensor neurotransmitters optogenetics channelrhodopsins sodium calcium DC gate Optogenetics p53 AsLOV2 LINuS LEXY MIP PMI Chlamydomonas reinhardtii ion channel electrophysiology molecular dynamics simulations membrane-protein interaction energy of membrane deformation CTMD method, residual hydrophobic mismatch microbial rhodopsin channelrhodopsin membrane current hippocampal neurons light stimulation channelrhodopsin-2 photoreceptor BLUF modular domain resonance Raman flash photolysis hybrid QM/MM simulation two-photon azobenzene photoswitch photoswitching photocontrol all-optical electrophysiology microbial rhodopsins ion channels LOV domains membrane potential intracellular trafficking protein–protein interaction signaling thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences This book provides an update for the rapidly developing technology known as “optogenetics”, which is the use of genetically encoded light-sensitive molecular elements (usually derived from lower organisms) to control or report various physiological and biochemical processes within the cell. Two ongoing clinical trials use optogenetic tools for vision restoration, and optogenetic strategies have been suggested as novel therapies for several neurological, psychiatric and cardiac disorders. This Special Issue comprises two reviews and seven experimental papers on different types of light-sensitive modules widely used in optogenetic studies. These papers demonstrate the efficiency and versatility of optogenetics and are expected to be equally relevant for advanced users and beginners considering using optogenetic tools in their research. 2021-05-01T15:49:51Z 2021-05-01T15:49:51Z 2020 book ONIX_20210501_9783039436736_1193 9783039436736 9783039436743 https://directory.doabooks.org/handle/20.500.12854/69447 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/3251 https://mdpi.com/books/pdfview/book/3251 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03943-674-3 10.3390/books978-3-03943-674-3 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783039436736 9783039436743 164 Basel, Switzerland open access |
| spellingShingle | optogenetic tools neuroscience calcium sensor voltage sensor neurotransmitters optogenetics channelrhodopsins sodium calcium DC gate Optogenetics p53 AsLOV2 LINuS LEXY MIP PMI Chlamydomonas reinhardtii ion channel electrophysiology molecular dynamics simulations membrane-protein interaction energy of membrane deformation CTMD method, residual hydrophobic mismatch microbial rhodopsin channelrhodopsin membrane current hippocampal neurons light stimulation channelrhodopsin-2 photoreceptor BLUF modular domain resonance Raman flash photolysis hybrid QM/MM simulation two-photon azobenzene photoswitch photoswitching photocontrol all-optical electrophysiology microbial rhodopsins ion channels LOV domains membrane potential intracellular trafficking protein–protein interaction signaling thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences The Advances and Applications of Optogenetics |
| title | The Advances and Applications of Optogenetics |
| title_full | The Advances and Applications of Optogenetics |
| title_fullStr | The Advances and Applications of Optogenetics |
| title_full_unstemmed | The Advances and Applications of Optogenetics |
| title_short | The Advances and Applications of Optogenetics |
| title_sort | advances and applications of optogenetics |
| topic | optogenetic tools neuroscience calcium sensor voltage sensor neurotransmitters optogenetics channelrhodopsins sodium calcium DC gate Optogenetics p53 AsLOV2 LINuS LEXY MIP PMI Chlamydomonas reinhardtii ion channel electrophysiology molecular dynamics simulations membrane-protein interaction energy of membrane deformation CTMD method, residual hydrophobic mismatch microbial rhodopsin channelrhodopsin membrane current hippocampal neurons light stimulation channelrhodopsin-2 photoreceptor BLUF modular domain resonance Raman flash photolysis hybrid QM/MM simulation two-photon azobenzene photoswitch photoswitching photocontrol all-optical electrophysiology microbial rhodopsins ion channels LOV domains membrane potential intracellular trafficking protein–protein interaction signaling thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| topic_facet | optogenetic tools neuroscience calcium sensor voltage sensor neurotransmitters optogenetics channelrhodopsins sodium calcium DC gate Optogenetics p53 AsLOV2 LINuS LEXY MIP PMI Chlamydomonas reinhardtii ion channel electrophysiology molecular dynamics simulations membrane-protein interaction energy of membrane deformation CTMD method, residual hydrophobic mismatch microbial rhodopsin channelrhodopsin membrane current hippocampal neurons light stimulation channelrhodopsin-2 photoreceptor BLUF modular domain resonance Raman flash photolysis hybrid QM/MM simulation two-photon azobenzene photoswitch photoswitching photocontrol all-optical electrophysiology microbial rhodopsins ion channels LOV domains membrane potential intracellular trafficking protein–protein interaction signaling thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| url | ONIX_20210501_9783039436736_1193 |