Vaccines against RNA Viruses
RNA viruses cause animal, human, and zoonotic diseases that affect millions of individuals, as is being exemplified by the devastating ongoing epidemic of the recently identified SARS-Cov-2. For years vaccines have had an enormous impact on overcoming the global burden of diseases. Nowadays, a vast...
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| Formaat: | Online |
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| Taal: | Engels |
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MDPI - Multidisciplinary Digital Publishing Institute
2021
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| Online toegang: | ONIX_20210501_9783039436231_1195 |
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| collection | Directory of Open Access Books |
| description | RNA viruses cause animal, human, and zoonotic diseases that affect millions of individuals, as is being exemplified by the devastating ongoing epidemic of the recently identified SARS-Cov-2. For years vaccines have had an enormous impact on overcoming the global burden of diseases. Nowadays, a vast number of different approaches, from purified inactivated and live attenuated viruses, nucleic acid (DNA or RNA) based candidates, virus-like particles, subunit elements, and recombinant viruses are been employed to combat viruses. However, for many of them efficient vaccines are not yet available. This will probably change dramatically with the current Covid-19 pandemic, as a vast variety of vaccinology approaches are being tested against it, with hundreds of candidates under development, dozens of them already in clinical trials, a fact that is breaking records in vaccine development and implementation. This is becoming possible thanks to the enormous work carried out during years to have the bases for a quick response, even against unknown pathogens, in an impressive short time. Here, results obtained with different vaccine´s methodological approaches against human (HIV, HCV, HRV) animal (PRRSV, PEDV, FMDV, VHSV) and zoonotic (RVF, WNV), RNA viruses are presented by field experts. |
| format | Online |
| id | doab-20.500.12854ir-69449 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-694492024-03-30T23:22:33Z Vaccines against RNA Viruses Saiz, Juan Carlos artificial protein polyepitope B- and T-cell HIV-1 immunogen epitopes of broadly neutralizing HIV-1 antibodies peptide mimic of discontinuous epitope immunogenicity birds vaccines West Nile virus flavivirus herd immunity porcine epidemic diarrhea virus RNA interference processivity factor intestine epithelial cells N gene rotavirus nanoparticle vaccine gnotobiotic pigs FMDV peptide vaccine single dose amount pig VHSV non-virion (NV) transcriptome profiling rainbow trout immune pathways Rift Valley fever virus (RVFV) modified vaccinia Ankara (MVA) cellular response neutralizing antibodies Gn Gc glycoproteins passive serum:virus transfer hepatitis C virus neutralising antibodies animal models immune responses PRRSV Mosaic T-cell DNA vaccine VACV PRRS cross protection heterologous virus challenge n/a thema EDItEUR::M Medicine and Nursing RNA viruses cause animal, human, and zoonotic diseases that affect millions of individuals, as is being exemplified by the devastating ongoing epidemic of the recently identified SARS-Cov-2. For years vaccines have had an enormous impact on overcoming the global burden of diseases. Nowadays, a vast number of different approaches, from purified inactivated and live attenuated viruses, nucleic acid (DNA or RNA) based candidates, virus-like particles, subunit elements, and recombinant viruses are been employed to combat viruses. However, for many of them efficient vaccines are not yet available. This will probably change dramatically with the current Covid-19 pandemic, as a vast variety of vaccinology approaches are being tested against it, with hundreds of candidates under development, dozens of them already in clinical trials, a fact that is breaking records in vaccine development and implementation. This is becoming possible thanks to the enormous work carried out during years to have the bases for a quick response, even against unknown pathogens, in an impressive short time. Here, results obtained with different vaccine´s methodological approaches against human (HIV, HCV, HRV) animal (PRRSV, PEDV, FMDV, VHSV) and zoonotic (RVF, WNV), RNA viruses are presented by field experts. 2021-05-01T15:49:54Z 2021-05-01T15:49:54Z 2020 book ONIX_20210501_9783039436231_1195 9783039436231 9783039436248 https://directory.doabooks.org/handle/20.500.12854/69449 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/3253 https://mdpi.com/books/pdfview/book/3253 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-03943-624-8 10.3390/books978-3-03943-624-8 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783039436231 9783039436248 166 Basel, Switzerland open access |
| spellingShingle | artificial protein polyepitope B- and T-cell HIV-1 immunogen epitopes of broadly neutralizing HIV-1 antibodies peptide mimic of discontinuous epitope immunogenicity birds vaccines West Nile virus flavivirus herd immunity porcine epidemic diarrhea virus RNA interference processivity factor intestine epithelial cells N gene rotavirus nanoparticle vaccine gnotobiotic pigs FMDV peptide vaccine single dose amount pig VHSV non-virion (NV) transcriptome profiling rainbow trout immune pathways Rift Valley fever virus (RVFV) modified vaccinia Ankara (MVA) cellular response neutralizing antibodies Gn Gc glycoproteins passive serum:virus transfer hepatitis C virus neutralising antibodies animal models immune responses PRRSV Mosaic T-cell DNA vaccine VACV PRRS cross protection heterologous virus challenge n/a thema EDItEUR::M Medicine and Nursing Vaccines against RNA Viruses |
| title | Vaccines against RNA Viruses |
| title_full | Vaccines against RNA Viruses |
| title_fullStr | Vaccines against RNA Viruses |
| title_full_unstemmed | Vaccines against RNA Viruses |
| title_short | Vaccines against RNA Viruses |
| title_sort | vaccines against rna viruses |
| topic | artificial protein polyepitope B- and T-cell HIV-1 immunogen epitopes of broadly neutralizing HIV-1 antibodies peptide mimic of discontinuous epitope immunogenicity birds vaccines West Nile virus flavivirus herd immunity porcine epidemic diarrhea virus RNA interference processivity factor intestine epithelial cells N gene rotavirus nanoparticle vaccine gnotobiotic pigs FMDV peptide vaccine single dose amount pig VHSV non-virion (NV) transcriptome profiling rainbow trout immune pathways Rift Valley fever virus (RVFV) modified vaccinia Ankara (MVA) cellular response neutralizing antibodies Gn Gc glycoproteins passive serum:virus transfer hepatitis C virus neutralising antibodies animal models immune responses PRRSV Mosaic T-cell DNA vaccine VACV PRRS cross protection heterologous virus challenge n/a thema EDItEUR::M Medicine and Nursing |
| topic_facet | artificial protein polyepitope B- and T-cell HIV-1 immunogen epitopes of broadly neutralizing HIV-1 antibodies peptide mimic of discontinuous epitope immunogenicity birds vaccines West Nile virus flavivirus herd immunity porcine epidemic diarrhea virus RNA interference processivity factor intestine epithelial cells N gene rotavirus nanoparticle vaccine gnotobiotic pigs FMDV peptide vaccine single dose amount pig VHSV non-virion (NV) transcriptome profiling rainbow trout immune pathways Rift Valley fever virus (RVFV) modified vaccinia Ankara (MVA) cellular response neutralizing antibodies Gn Gc glycoproteins passive serum:virus transfer hepatitis C virus neutralising antibodies animal models immune responses PRRSV Mosaic T-cell DNA vaccine VACV PRRS cross protection heterologous virus challenge n/a thema EDItEUR::M Medicine and Nursing |
| url | ONIX_20210501_9783039436231_1195 |