Chapter Nature-Inspired Nanotechnology and Smart Magnetic Activation: Two Groundbreaking Approaches Toward a New Generation of Biomaterials for Hard Tissue Regeneration
Diatomite is a natural porous silica material of sedimentary origin, formed by remains of diatom skeletons called “frustules.” The abundance in many areas of the world and the peculiar physico-chemical properties made diatomite an intriguing material for several applications ranging from food produc...
সংরক্ষণ করুন:
| প্রধান লেখক: | , , , , , , , , |
|---|---|
| বিন্যাস: | Online |
| ভাষা: | ইংরেজি |
| প্রকাশিত: |
InTechOpen
2021
|
| বিষয়গুলি: | |
| অনলাইন ব্যবহার করুন: | ONIX_20210602_10.5772/63229_268 |
| ট্যাগগুলো: |
কোনো ট্যাগ নেই, প্রথমজন হিসাবে ট্যাগ করুন!
|
| _version_ | 1869528637547479040 |
|---|---|
| author | Sprio, Simone Sandri, Monica Iafisco, Michele Panseri, Silvia Montesi, Monica Ruffini, Andrea Adamiano, Alessio Ballardini, Alberto Tampieri, Anna |
| author_browse | Adamiano, Alessio Ballardini, Alberto Iafisco, Michele Montesi, Monica Panseri, Silvia Ruffini, Andrea Sandri, Monica Sprio, Simone Tampieri, Anna |
| author_facet | Sprio, Simone Sandri, Monica Iafisco, Michele Panseri, Silvia Montesi, Monica Ruffini, Andrea Adamiano, Alessio Ballardini, Alberto Tampieri, Anna |
| author_sort | Sprio, Simone |
| collection | Directory of Open Access Books |
| description | Diatomite is a natural porous silica material of sedimentary origin, formed by remains of diatom skeletons called “frustules.” The abundance in many areas of the world and the peculiar physico-chemical properties made diatomite an intriguing material for several applications ranging from food production to pharmaceutics. However, diatomite is a material still rarely used in biomedical applications. In this chapter, the properties of diatom frustules reduced to nanoparticles, with an average diameter less than 350 nm, as potential drug vectors are described. Their biocompatibility, cellular uptake, and capability to transport molecules inside cancer cells are discussed. Preliminary studies of in vivo toxicity are also presented. |
| format | Online |
| id | doab-20.500.12854ir-70186 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | InTechOpen |
| publisherStr | InTechOpen |
| record_format | ojs |
| spelling | doab-20.500.12854ir-701862024-04-05T17:31:09Z Chapter Nature-Inspired Nanotechnology and Smart Magnetic Activation: Two Groundbreaking Approaches Toward a New Generation of Biomaterials for Hard Tissue Regeneration Sprio, Simone Sandri, Monica Iafisco, Michele Panseri, Silvia Montesi, Monica Ruffini, Andrea Adamiano, Alessio Ballardini, Alberto Tampieri, Anna diatomite, porous material, nanovector, bioconjugation, drug delivery thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSP Hydrobiology::PSPA Phycology (algae and seaweed) Diatomite is a natural porous silica material of sedimentary origin, formed by remains of diatom skeletons called “frustules.” The abundance in many areas of the world and the peculiar physico-chemical properties made diatomite an intriguing material for several applications ranging from food production to pharmaceutics. However, diatomite is a material still rarely used in biomedical applications. In this chapter, the properties of diatom frustules reduced to nanoparticles, with an average diameter less than 350 nm, as potential drug vectors are described. Their biocompatibility, cellular uptake, and capability to transport molecules inside cancer cells are discussed. Preliminary studies of in vivo toxicity are also presented. 2021-02-10T12:58:18Z 2021-06-02T10:07:58Z 2016 chapter ONIX_20210602_10.5772/63229_268 https://library.oapen.org/handle/20.500.12657/49154 https://directory.doabooks.org/handle/20.500.12854/70186 eng open access image/jpeg image/jpeg image/jpeg n/a n/a n/a https://library.oapen.org/bitstream/20.500.12657/49154/1/50571.pdf https://library.oapen.org/bitstream/20.500.12657/49154/1/50571.pdf https://library.oapen.org/bitstream/20.500.12657/49154/1/50571.pdf InTechOpen 10.5772/63229 10.5772/63229 035ecc65-6737-43cf-a13a-6bdf67ce01f4 open access |
| spellingShingle | diatomite, porous material, nanovector, bioconjugation, drug delivery thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSP Hydrobiology::PSPA Phycology (algae and seaweed) Sprio, Simone Sandri, Monica Iafisco, Michele Panseri, Silvia Montesi, Monica Ruffini, Andrea Adamiano, Alessio Ballardini, Alberto Tampieri, Anna Chapter Nature-Inspired Nanotechnology and Smart Magnetic Activation: Two Groundbreaking Approaches Toward a New Generation of Biomaterials for Hard Tissue Regeneration |
| title | Chapter Nature-Inspired Nanotechnology and Smart Magnetic Activation: Two Groundbreaking Approaches Toward a New Generation of Biomaterials for Hard Tissue Regeneration |
| title_full | Chapter Nature-Inspired Nanotechnology and Smart Magnetic Activation: Two Groundbreaking Approaches Toward a New Generation of Biomaterials for Hard Tissue Regeneration |
| title_fullStr | Chapter Nature-Inspired Nanotechnology and Smart Magnetic Activation: Two Groundbreaking Approaches Toward a New Generation of Biomaterials for Hard Tissue Regeneration |
| title_full_unstemmed | Chapter Nature-Inspired Nanotechnology and Smart Magnetic Activation: Two Groundbreaking Approaches Toward a New Generation of Biomaterials for Hard Tissue Regeneration |
| title_short | Chapter Nature-Inspired Nanotechnology and Smart Magnetic Activation: Two Groundbreaking Approaches Toward a New Generation of Biomaterials for Hard Tissue Regeneration |
| title_sort | chapter nature inspired nanotechnology and smart magnetic activation two groundbreaking approaches toward a new generation of biomaterials for hard tissue regeneration |
| topic | diatomite, porous material, nanovector, bioconjugation, drug delivery thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSP Hydrobiology::PSPA Phycology (algae and seaweed) |
| topic_facet | diatomite, porous material, nanovector, bioconjugation, drug delivery thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSP Hydrobiology::PSPA Phycology (algae and seaweed) |
| url | ONIX_20210602_10.5772/63229_268 |
| work_keys_str_mv | AT spriosimone chapternatureinspirednanotechnologyandsmartmagneticactivationtwogroundbreakingapproachestowardanewgenerationofbiomaterialsforhardtissueregeneration AT sandrimonica chapternatureinspirednanotechnologyandsmartmagneticactivationtwogroundbreakingapproachestowardanewgenerationofbiomaterialsforhardtissueregeneration AT iafiscomichele chapternatureinspirednanotechnologyandsmartmagneticactivationtwogroundbreakingapproachestowardanewgenerationofbiomaterialsforhardtissueregeneration AT panserisilvia chapternatureinspirednanotechnologyandsmartmagneticactivationtwogroundbreakingapproachestowardanewgenerationofbiomaterialsforhardtissueregeneration AT montesimonica chapternatureinspirednanotechnologyandsmartmagneticactivationtwogroundbreakingapproachestowardanewgenerationofbiomaterialsforhardtissueregeneration AT ruffiniandrea chapternatureinspirednanotechnologyandsmartmagneticactivationtwogroundbreakingapproachestowardanewgenerationofbiomaterialsforhardtissueregeneration AT adamianoalessio chapternatureinspirednanotechnologyandsmartmagneticactivationtwogroundbreakingapproachestowardanewgenerationofbiomaterialsforhardtissueregeneration AT ballardinialberto chapternatureinspirednanotechnologyandsmartmagneticactivationtwogroundbreakingapproachestowardanewgenerationofbiomaterialsforhardtissueregeneration AT tampierianna chapternatureinspirednanotechnologyandsmartmagneticactivationtwogroundbreakingapproachestowardanewgenerationofbiomaterialsforhardtissueregeneration |