Chapter Sorption Detoxification as an Addition to Conventional Therapy of Acute Radiation Sickness and Iatrogenic Leukopenia
Leukopenia is an essential part of the clinical course of acute radiation sickness and is a side effect of anti-cancer treatment. In both situations, the main factors which determine the survival are the degree of bone marrow suppression and gastrointestinal tract damage due to the presence of a lar...
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| Định dạng: | Online |
| Ngôn ngữ: | Tiếng Anh |
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InTechOpen
2021
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| Truy cập trực tuyến: | ONIX_20210602_10.5772/intechopen.85690_426 |
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| author | Sarnatskaya, V. V. Snezhkova, E. A. Chekhun, Vasyl F. Vg, Nikolaev Bilous, Anatoliy G. Shevchuk, O. O. Badakhivska, Kvitoslava I. Sakhno, L. A. |
| author_browse | Badakhivska, Kvitoslava I. Bilous, Anatoliy G. Chekhun, Vasyl F. Sakhno, L. A. Sarnatskaya, V. V. Shevchuk, O. O. Snezhkova, E. A. Vg, Nikolaev |
| author_facet | Sarnatskaya, V. V. Snezhkova, E. A. Chekhun, Vasyl F. Vg, Nikolaev Bilous, Anatoliy G. Shevchuk, O. O. Badakhivska, Kvitoslava I. Sakhno, L. A. |
| author_sort | Sarnatskaya, V. V. |
| collection | Directory of Open Access Books |
| description | Leukopenia is an essential part of the clinical course of acute radiation sickness and is a side effect of anti-cancer treatment. In both situations, the main factors which determine the survival are the degree of bone marrow suppression and gastrointestinal tract damage due to the presence of a large pool of fast-dividing cells. Leuko- and neutropenia are main limiting factors which may contribute to chemotherapy failure. Hematopoietic cytokines the part of conventional therapy in this field, but their effects require boosting. That is why the use of means and methods of adsorption therapy is considered promising. Sorption therapy creates a basis for sorption detoxification, a doctrine of curative measures directed to the removal of toxic endogenous or exogenous compounds from body fluids. The most widely used types are the purification of blood or its components (hemosorption), oral administration of sorption materials (enterosorption) and application-sorption therapy of wounds and burns. In this chapter, the results of early and recent research and prospects for the use of carbon adsorption therapy for the treatment of acute radiation sickness and cytostatic myelosuppression are discussed. |
| format | Online |
| id | doab-20.500.12854ir-70187 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | InTechOpen |
| publisherStr | InTechOpen |
| record_format | ojs |
| spelling | doab-20.500.12854ir-701872025-08-13T14:11:34Z Chapter Sorption Detoxification as an Addition to Conventional Therapy of Acute Radiation Sickness and Iatrogenic Leukopenia Sarnatskaya, V. V. Snezhkova, E. A. Chekhun, Vasyl F. Vg, Nikolaev Bilous, Anatoliy G. Shevchuk, O. O. Badakhivska, Kvitoslava I. Sakhno, L. A. leukopenia, ionizing irradiation, anti-cancer chemotherapy, granulocyte colony stimulating factor, hemosorption, enterosorption, application-sorption therapy thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKF Pathology::MKFM Medical microbiology and virology thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKF Pathology::MKFM Medical microbiology and virology Leukopenia is an essential part of the clinical course of acute radiation sickness and is a side effect of anti-cancer treatment. In both situations, the main factors which determine the survival are the degree of bone marrow suppression and gastrointestinal tract damage due to the presence of a large pool of fast-dividing cells. Leuko- and neutropenia are main limiting factors which may contribute to chemotherapy failure. Hematopoietic cytokines the part of conventional therapy in this field, but their effects require boosting. That is why the use of means and methods of adsorption therapy is considered promising. Sorption therapy creates a basis for sorption detoxification, a doctrine of curative measures directed to the removal of toxic endogenous or exogenous compounds from body fluids. The most widely used types are the purification of blood or its components (hemosorption), oral administration of sorption materials (enterosorption) and application-sorption therapy of wounds and burns. In this chapter, the results of early and recent research and prospects for the use of carbon adsorption therapy for the treatment of acute radiation sickness and cytostatic myelosuppression are discussed. 2021-06-02T10:11:57Z 2019 chapter ONIX_20210602_10.5772/intechopen.85690_426 https://library.oapen.org/handle/20.500.12657/49312 https://directory.doabooks.org/handle/20.500.12854/70187 eng open access image/jpeg image/jpeg image/jpeg n/a n/a n/a https://library.oapen.org/bitstream/20.500.12657/49312/1/66927.pdf https://library.oapen.org/bitstream/20.500.12657/49312/1/66927.pdf https://library.oapen.org/bitstream/20.500.12657/49312/1/66927.pdf InTechOpen 10.5772/intechopen.85690 10.5772/intechopen.85690 035ecc65-6737-43cf-a13a-6bdf67ce01f4 open access |
| spellingShingle | leukopenia, ionizing irradiation, anti-cancer chemotherapy, granulocyte colony stimulating factor, hemosorption, enterosorption, application-sorption therapy thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKF Pathology::MKFM Medical microbiology and virology thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKF Pathology::MKFM Medical microbiology and virology Sarnatskaya, V. V. Snezhkova, E. A. Chekhun, Vasyl F. Vg, Nikolaev Bilous, Anatoliy G. Shevchuk, O. O. Badakhivska, Kvitoslava I. Sakhno, L. A. Chapter Sorption Detoxification as an Addition to Conventional Therapy of Acute Radiation Sickness and Iatrogenic Leukopenia |
| title | Chapter Sorption Detoxification as an Addition to Conventional Therapy of Acute Radiation Sickness and Iatrogenic Leukopenia |
| title_full | Chapter Sorption Detoxification as an Addition to Conventional Therapy of Acute Radiation Sickness and Iatrogenic Leukopenia |
| title_fullStr | Chapter Sorption Detoxification as an Addition to Conventional Therapy of Acute Radiation Sickness and Iatrogenic Leukopenia |
| title_full_unstemmed | Chapter Sorption Detoxification as an Addition to Conventional Therapy of Acute Radiation Sickness and Iatrogenic Leukopenia |
| title_short | Chapter Sorption Detoxification as an Addition to Conventional Therapy of Acute Radiation Sickness and Iatrogenic Leukopenia |
| title_sort | chapter sorption detoxification as an addition to conventional therapy of acute radiation sickness and iatrogenic leukopenia |
| topic | leukopenia, ionizing irradiation, anti-cancer chemotherapy, granulocyte colony stimulating factor, hemosorption, enterosorption, application-sorption therapy thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKF Pathology::MKFM Medical microbiology and virology thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKF Pathology::MKFM Medical microbiology and virology |
| topic_facet | leukopenia, ionizing irradiation, anti-cancer chemotherapy, granulocyte colony stimulating factor, hemosorption, enterosorption, application-sorption therapy thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKF Pathology::MKFM Medical microbiology and virology thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKF Pathology::MKFM Medical microbiology and virology |
| url | ONIX_20210602_10.5772/intechopen.85690_426 |
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