Chapter Clinical Trials in Paediatrics — Regulatory and Methodological Aspects
The photoautotrophic cyanobacterium Synechocystis PCC6803 has received much attention as a model photosynthetic cell factory for the production of a range of important biotech products. The biomass remaining from this activity may then have further utility in processes such as metal bioremediation....
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| Автори: | , , , , , |
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| Формат: | Online |
| Мова: | Англійська |
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InTechOpen
2021
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| Предмети: | |
| Онлайн доступ: | ONIX_20210602_10.5772/60611_248 |
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| _version_ | 1869526710066610176 |
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| author | Ceci, Adriana Giannuzzi, Viviana Bonifazi, Donato Felisi, Mariagrazia Bonifazi, Fedele Ruggieri, Lucia |
| author_browse | Bonifazi, Donato Bonifazi, Fedele Ceci, Adriana Felisi, Mariagrazia Giannuzzi, Viviana Ruggieri, Lucia |
| author_facet | Ceci, Adriana Giannuzzi, Viviana Bonifazi, Donato Felisi, Mariagrazia Bonifazi, Fedele Ruggieri, Lucia |
| author_sort | Ceci, Adriana |
| collection | Directory of Open Access Books |
| description | The photoautotrophic cyanobacterium Synechocystis PCC6803 has received much attention as a model photosynthetic cell factory for the production of a range of important biotech products. The biomass remaining from this activity may then have further utility in processes such as metal bioremediation. In addition Synechocystis being an inhabitant of many natural aquatic environments is seen as an environmentally friendly alternative to using chemical precipitation methodologies for metal remediation. Synechocystis produces a range of extracellular polysaccharide substances (EPS) that can undergo modification as a function of culture age and growth nutrients which have been implicated in metal biosorption. Many studies have demonstrated that high levels of charged groups present in EPS are important in forming polymeric matrices with metallic ions allowing their biosorption. Genetic studies has revealed genes involved in such metal binding indicating that EPS can be modified for potential enhancement of binding or modification of the types of metals bound. The utility of metal binding to live and dead biomass of Synechocystis has been demonstrated for a range of metals including Cr(VI), Cd(II), Cu(II), Pb(II), Sb, Ni(II), Mn(II), Mn(IV), As(III), As(V), Cs and Hg. The potential of using Synechocystis as a biosorption platform is discussed. |
| format | Online |
| id | doab-20.500.12854ir-70431 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | InTechOpen |
| publisherStr | InTechOpen |
| record_format | ojs |
| spelling | doab-20.500.12854ir-704312024-04-09T11:41:56Z Chapter Clinical Trials in Paediatrics — Regulatory and Methodological Aspects Ceci, Adriana Giannuzzi, Viviana Bonifazi, Donato Felisi, Mariagrazia Bonifazi, Fedele Ruggieri, Lucia Synechocystis, EPS, metal biosorption, metal binding, metal remediation thema EDItEUR::R Earth Sciences, Geography, Environment, Planning::RB Earth sciences::RBK Hydrology and the hydrosphere The photoautotrophic cyanobacterium Synechocystis PCC6803 has received much attention as a model photosynthetic cell factory for the production of a range of important biotech products. The biomass remaining from this activity may then have further utility in processes such as metal bioremediation. In addition Synechocystis being an inhabitant of many natural aquatic environments is seen as an environmentally friendly alternative to using chemical precipitation methodologies for metal remediation. Synechocystis produces a range of extracellular polysaccharide substances (EPS) that can undergo modification as a function of culture age and growth nutrients which have been implicated in metal biosorption. Many studies have demonstrated that high levels of charged groups present in EPS are important in forming polymeric matrices with metallic ions allowing their biosorption. Genetic studies has revealed genes involved in such metal binding indicating that EPS can be modified for potential enhancement of binding or modification of the types of metals bound. The utility of metal binding to live and dead biomass of Synechocystis has been demonstrated for a range of metals including Cr(VI), Cd(II), Cu(II), Pb(II), Sb, Ni(II), Mn(II), Mn(IV), As(III), As(V), Cs and Hg. The potential of using Synechocystis as a biosorption platform is discussed. 2021-02-10T12:58:18Z 2021-06-02T10:07:35Z 2015 chapter ONIX_20210602_10.5772/60611_248 https://library.oapen.org/handle/20.500.12657/49134 https://directory.doabooks.org/handle/20.500.12854/70431 eng open access image/jpeg image/jpeg n/a n/a https://library.oapen.org/bitstream/20.500.12657/49134/1/48435.pdf https://library.oapen.org/bitstream/20.500.12657/49134/1/48435.pdf InTechOpen 10.5772/60611 10.5772/60611 035ecc65-6737-43cf-a13a-6bdf67ce01f4 open access |
| spellingShingle | Synechocystis, EPS, metal biosorption, metal binding, metal remediation thema EDItEUR::R Earth Sciences, Geography, Environment, Planning::RB Earth sciences::RBK Hydrology and the hydrosphere Ceci, Adriana Giannuzzi, Viviana Bonifazi, Donato Felisi, Mariagrazia Bonifazi, Fedele Ruggieri, Lucia Chapter Clinical Trials in Paediatrics — Regulatory and Methodological Aspects |
| title | Chapter Clinical Trials in Paediatrics — Regulatory and Methodological Aspects |
| title_full | Chapter Clinical Trials in Paediatrics — Regulatory and Methodological Aspects |
| title_fullStr | Chapter Clinical Trials in Paediatrics — Regulatory and Methodological Aspects |
| title_full_unstemmed | Chapter Clinical Trials in Paediatrics — Regulatory and Methodological Aspects |
| title_short | Chapter Clinical Trials in Paediatrics — Regulatory and Methodological Aspects |
| title_sort | chapter clinical trials in paediatrics regulatory and methodological aspects |
| topic | Synechocystis, EPS, metal biosorption, metal binding, metal remediation thema EDItEUR::R Earth Sciences, Geography, Environment, Planning::RB Earth sciences::RBK Hydrology and the hydrosphere |
| topic_facet | Synechocystis, EPS, metal biosorption, metal binding, metal remediation thema EDItEUR::R Earth Sciences, Geography, Environment, Planning::RB Earth sciences::RBK Hydrology and the hydrosphere |
| url | ONIX_20210602_10.5772/60611_248 |
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