Chapter Nucleated Red Blood Cells Contribute to the Host Immune Response Against Pathogens
It has recently come to light that nucleated red blood cells (RBCs) of fish, amphibians, reptiles and birds are multifunctional cells, because in addition to being involved in gas exchange and transport, it has also been reported that they respond to pathogens by means of (i) phagocytosis, (ii) anti...
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| Materyal Türü: | Online |
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InTechOpen
2021
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| Konular: | |
| Online Erişim: | ONIX_20210602_10.5772/intechopen.80545_430 |
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| _version_ | 1869520186781990912 |
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| author | Nombela, Ivan Chico, Veronica Puente-Marin, Sara Ortega-Villaizan, M. |
| author_browse | Chico, Veronica Nombela, Ivan Ortega-Villaizan, M. Puente-Marin, Sara |
| author_facet | Nombela, Ivan Chico, Veronica Puente-Marin, Sara Ortega-Villaizan, M. |
| author_sort | Nombela, Ivan |
| collection | Directory of Open Access Books |
| description | It has recently come to light that nucleated red blood cells (RBCs) of fish, amphibians, reptiles and birds are multifunctional cells, because in addition to being involved in gas exchange and transport, it has also been reported that they respond to pathogens by means of (i) phagocytosis, (ii) antigen presentation, (iii) production of cytokines and antimicrobial peptides, (iv) regulation of complement system, and (v) exerting paracrine molecular communication with other immune cells and modulating their functions. Similarly, human cord blood nucleated RBCs have been shown to exert a regulatory function in the innate immune response, by means of the suppression of the production of inflammatory cytokines. This chapter comprises the study of the implications of nucleated RBCs as mediators of both branches of immune system (innate and adaptive immune responses). |
| format | Online |
| id | doab-20.500.12854ir-70638 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | InTechOpen |
| publisherStr | InTechOpen |
| record_format | ojs |
| spelling | doab-20.500.12854ir-706382025-05-09T11:23:43Z Chapter Nucleated Red Blood Cells Contribute to the Host Immune Response Against Pathogens Nombela, Ivan Chico, Veronica Puente-Marin, Sara Ortega-Villaizan, M. nucleated red blood cells, erythrocytes, immune response, cytokines, antimicrobial peptides, virus, antigen presentation It has recently come to light that nucleated red blood cells (RBCs) of fish, amphibians, reptiles and birds are multifunctional cells, because in addition to being involved in gas exchange and transport, it has also been reported that they respond to pathogens by means of (i) phagocytosis, (ii) antigen presentation, (iii) production of cytokines and antimicrobial peptides, (iv) regulation of complement system, and (v) exerting paracrine molecular communication with other immune cells and modulating their functions. Similarly, human cord blood nucleated RBCs have been shown to exert a regulatory function in the innate immune response, by means of the suppression of the production of inflammatory cytokines. This chapter comprises the study of the implications of nucleated RBCs as mediators of both branches of immune system (innate and adaptive immune responses). 2021-06-03T02:10:48Z 2021-06-03T02:10:48Z 2021-06-02T10:12:02Z 2019 chapter ONIX_20210602_10.5772/intechopen.80545_430 https://library.oapen.org/handle/20.500.12657/49316 https://directory.doabooks.org/handle/20.500.12854/70638 eng open access image/jpeg image/jpeg image/jpeg n/a n/a n/a https://library.oapen.org/bitstream/20.500.12657/49316/1/63797.pdf https://library.oapen.org/bitstream/20.500.12657/49316/1/63797.pdf https://library.oapen.org/bitstream/20.500.12657/49316/1/63797.pdf InTechOpen 10.5772/intechopen.80545 10.5772/intechopen.80545 035ecc65-6737-43cf-a13a-6bdf67ce01f4 H2020 European Research Council 178e65b9-dd53-4922-b85c-0aaa74fce079 European Research Council (ERC) EU collection 639249 open access |
| spellingShingle | nucleated red blood cells, erythrocytes, immune response, cytokines, antimicrobial peptides, virus, antigen presentation Nombela, Ivan Chico, Veronica Puente-Marin, Sara Ortega-Villaizan, M. Chapter Nucleated Red Blood Cells Contribute to the Host Immune Response Against Pathogens |
| title | Chapter Nucleated Red Blood Cells Contribute to the Host Immune Response Against Pathogens |
| title_full | Chapter Nucleated Red Blood Cells Contribute to the Host Immune Response Against Pathogens |
| title_fullStr | Chapter Nucleated Red Blood Cells Contribute to the Host Immune Response Against Pathogens |
| title_full_unstemmed | Chapter Nucleated Red Blood Cells Contribute to the Host Immune Response Against Pathogens |
| title_short | Chapter Nucleated Red Blood Cells Contribute to the Host Immune Response Against Pathogens |
| title_sort | chapter nucleated red blood cells contribute to the host immune response against pathogens |
| topic | nucleated red blood cells, erythrocytes, immune response, cytokines, antimicrobial peptides, virus, antigen presentation |
| topic_facet | nucleated red blood cells, erythrocytes, immune response, cytokines, antimicrobial peptides, virus, antigen presentation |
| url | ONIX_20210602_10.5772/intechopen.80545_430 |
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