New Therapies in the Field of Rheumatology
In recent years, the long term prognosis of patients with rheumatic disease has dramatically improved, due to the enormous advances in the understanding of the pathogenesis of these diseases that have led to the development of drugs targeting the molecules directly involved in the inflammatory respo...
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| Idioma: | anglès |
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Frontiers Media SA
2021
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| Accés en línia: | ONIX_20211118_9782889635450_829 |
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| description | In recent years, the long term prognosis of patients with rheumatic disease has dramatically improved, due to the enormous advances in the understanding of the pathogenesis of these diseases that have led to the development of drugs targeting the molecules directly involved in the inflammatory response. The development of these biological drugs has radically changed the therapeutic approach of inflammatory rheumatic diseases, mainly in patients resistant to standard treatment. Also in the field of conventional therapy, many new data have confirmed the effectiveness of “old” drugs, such as hydroxychloroquine, methotrexate and azathioprine, demonstrating several additional beneficial properties for the treatment of Systemic Lupus Erythematosus (SLE), Rheumatoid Arthritis (RA) or other autoimmune diseases. Moreover, immunosuppressant developed to prevent graft rejection such as mycophenolate or tacrolimus have been demonstrated to have an important role in the treatment of rheumatic patients. Beside the well defined anti-inflammatory properties of biological and synthetic anti-rheumatic drugs, a number of additional beneficial effects have been suggested, that have been hypothesized to prevent long term complications of autoimmune diseases, such as accelerated atherosclerosis, increased cardiovascular risk and osteoporosis. This Research Topic collects new information regarding safety and effectiveness of new and old drugs for the treatment of RA, SLE, or other autoimmune diseases. |
| format | Online |
| id | doab-20.500.12854ir-73697 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | Frontiers Media SA |
| publisherStr | Frontiers Media SA |
| record_format | ojs |
| spelling | doab-20.500.12854ir-736972024-04-04T19:19:54Z New Therapies in the Field of Rheumatology Gerosa, Maria Beatrice Chighizola, Cecilia Jakobsson, Per-Johan autoimmune diseases rheumatoid arthritis systemic lupus erythematosus disease modifing anti- rheumatic drugs biological therapies thema EDItEUR::P Mathematics and Science::PD Science: general issues thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology In recent years, the long term prognosis of patients with rheumatic disease has dramatically improved, due to the enormous advances in the understanding of the pathogenesis of these diseases that have led to the development of drugs targeting the molecules directly involved in the inflammatory response. The development of these biological drugs has radically changed the therapeutic approach of inflammatory rheumatic diseases, mainly in patients resistant to standard treatment. Also in the field of conventional therapy, many new data have confirmed the effectiveness of “old” drugs, such as hydroxychloroquine, methotrexate and azathioprine, demonstrating several additional beneficial properties for the treatment of Systemic Lupus Erythematosus (SLE), Rheumatoid Arthritis (RA) or other autoimmune diseases. Moreover, immunosuppressant developed to prevent graft rejection such as mycophenolate or tacrolimus have been demonstrated to have an important role in the treatment of rheumatic patients. Beside the well defined anti-inflammatory properties of biological and synthetic anti-rheumatic drugs, a number of additional beneficial effects have been suggested, that have been hypothesized to prevent long term complications of autoimmune diseases, such as accelerated atherosclerosis, increased cardiovascular risk and osteoporosis. This Research Topic collects new information regarding safety and effectiveness of new and old drugs for the treatment of RA, SLE, or other autoimmune diseases. 2021-11-18T16:22:50Z 2021-11-18T16:22:50Z 2020 book ONIX_20211118_9782889635450_829 9782889635450 https://directory.doabooks.org/handle/20.500.12854/73697 eng image/jpeg Attribution 4.0 International https://www.frontiersin.org/research-topics/7952/new-therapies-in-the-field-of-rheumatology https://www.frontiersin.org/research-topics/7952/new-therapies-in-the-field-of-rheumatology Frontiers Media SA 10.3389/978-2-88963-545-0 10.3389/978-2-88963-545-0 bf5ce210-e72e-4860-ba9b-c305640ff3ae 9782889635450 144 open access |
| spellingShingle | autoimmune diseases rheumatoid arthritis systemic lupus erythematosus disease modifing anti- rheumatic drugs biological therapies thema EDItEUR::P Mathematics and Science::PD Science: general issues thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology New Therapies in the Field of Rheumatology |
| title | New Therapies in the Field of Rheumatology |
| title_full | New Therapies in the Field of Rheumatology |
| title_fullStr | New Therapies in the Field of Rheumatology |
| title_full_unstemmed | New Therapies in the Field of Rheumatology |
| title_short | New Therapies in the Field of Rheumatology |
| title_sort | new therapies in the field of rheumatology |
| topic | autoimmune diseases rheumatoid arthritis systemic lupus erythematosus disease modifing anti- rheumatic drugs biological therapies thema EDItEUR::P Mathematics and Science::PD Science: general issues thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology |
| topic_facet | autoimmune diseases rheumatoid arthritis systemic lupus erythematosus disease modifing anti- rheumatic drugs biological therapies thema EDItEUR::P Mathematics and Science::PD Science: general issues thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology |
| url | ONIX_20211118_9782889635450_829 |