Radioimmunotherapy – Translational Opportunities and Challenges
Surgery, chemotherapy and radiotherapy remain the three primary approaches for treating the majority of cancers. Although the primary aim of radiotherapy is to inhibit tumor cell proliferation and induce tumor cell death by inducing DNA double-strand breaks, it is also known to have a number of immu...
-д хадгалсан:
| Формат: | Online |
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| Хэл сонгох: | англи |
| Хэвлэсэн: |
Frontiers Media SA
2021
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| Нөхцлүүд: | |
| Онлайн хандалт: | ONIX_20211118_9782889636150_889 |
| Шошгууд: |
Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!
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| _version_ | 1869515568456925184 |
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| collection | Directory of Open Access Books |
| description | Surgery, chemotherapy and radiotherapy remain the three primary approaches for treating the majority of cancers. Although the primary aim of radiotherapy is to inhibit tumor cell proliferation and induce tumor cell death by inducing DNA double-strand breaks, it is also known to have a number of immunological effects, the manipulation of which could enhance clinical efficacy. Recent insights into the immunomodulatory capacity of tumours, and the development of approaches to therapeutically exploit these have prompted the emergence of a range of immunotherapeutic approaches for inducing and enhancing robust, protective anti-tumor immunity. Combining radiotherapy with immunotherapy (radioimmunotherapy) therefore has significant clinical potential. The aim of this Research Topic is to collate primary articles, reviews and opinion pieces on the complex reciprocal relationships between the immune system, tumors and the tumour microenvironment, and the stimulatory and suppressive effects of radiotherapy on innate and adaptive immunity in the pre-clinical and clinical settings. |
| format | Online |
| id | doab-20.500.12854ir-73757 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2021 |
| publishDateRange | 2021 |
| publishDateSort | 2021 |
| publisher | Frontiers Media SA |
| publisherStr | Frontiers Media SA |
| record_format | ojs |
| spelling | doab-20.500.12854ir-737572024-03-31T13:10:37Z Radioimmunotherapy – Translational Opportunities and Challenges Gaipl, Udo S. Multhoff, Gabriele Graham Pockley, Alan Rödel, Franz translational reseach Immunotherapy Radiotherapy translational radioimmunotherapy Radioimmunotherapy thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology Surgery, chemotherapy and radiotherapy remain the three primary approaches for treating the majority of cancers. Although the primary aim of radiotherapy is to inhibit tumor cell proliferation and induce tumor cell death by inducing DNA double-strand breaks, it is also known to have a number of immunological effects, the manipulation of which could enhance clinical efficacy. Recent insights into the immunomodulatory capacity of tumours, and the development of approaches to therapeutically exploit these have prompted the emergence of a range of immunotherapeutic approaches for inducing and enhancing robust, protective anti-tumor immunity. Combining radiotherapy with immunotherapy (radioimmunotherapy) therefore has significant clinical potential. The aim of this Research Topic is to collate primary articles, reviews and opinion pieces on the complex reciprocal relationships between the immune system, tumors and the tumour microenvironment, and the stimulatory and suppressive effects of radiotherapy on innate and adaptive immunity in the pre-clinical and clinical settings. 2021-11-18T16:24:10Z 2021-11-18T16:24:10Z 2020 book ONIX_20211118_9782889636150_889 9782889636150 https://directory.doabooks.org/handle/20.500.12854/73757 eng image/jpeg Attribution 4.0 International https://www.frontiersin.org/research-topics/7261/radioimmunotherapy---translational-opportunities-and-challenges https://www.frontiersin.org/research-topics/7261/radioimmunotherapy---translational-opportunities-and-challenges Frontiers Media SA 10.3389/978-2-88963-615-0 10.3389/978-2-88963-615-0 bf5ce210-e72e-4860-ba9b-c305640ff3ae 9782889636150 144 open access |
| spellingShingle | translational reseach Immunotherapy Radiotherapy translational radioimmunotherapy Radioimmunotherapy thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology Radioimmunotherapy – Translational Opportunities and Challenges |
| title | Radioimmunotherapy – Translational Opportunities and Challenges |
| title_full | Radioimmunotherapy – Translational Opportunities and Challenges |
| title_fullStr | Radioimmunotherapy – Translational Opportunities and Challenges |
| title_full_unstemmed | Radioimmunotherapy – Translational Opportunities and Challenges |
| title_short | Radioimmunotherapy – Translational Opportunities and Challenges |
| title_sort | radioimmunotherapy translational opportunities and challenges |
| topic | translational reseach Immunotherapy Radiotherapy translational radioimmunotherapy Radioimmunotherapy thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology |
| topic_facet | translational reseach Immunotherapy Radiotherapy translational radioimmunotherapy Radioimmunotherapy thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology |
| url | ONIX_20211118_9782889636150_889 |