Asymmetry in Biological Homochirality

Chirality, or handedness, is a fundamental physical characteristic, which spans the length scales ranging from elementary particles to the chiral asymmetry of spiral galaxies. The way in which chirality in chemistry, or molecular handedness, may have emerged in a primitive terrestrial environment, a...

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Gepubliceerd in: MDPI - Multidisciplinary Digital Publishing Institute 2022
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description Chirality, or handedness, is a fundamental physical characteristic, which spans the length scales ranging from elementary particles to the chiral asymmetry of spiral galaxies. The way in which chirality in chemistry, or molecular handedness, may have emerged in a primitive terrestrial environment, and how it can be triggered, amplified, and transferred, are deeply challenging problems rooted in both fundamental scientific interests and the technological potentials for science and society. Chirality constitutes a unifying feature of the living world and is a prime driving force for molecular selection and genetic evolution in biology. In this book, we offer a selection of five distinct approaches to this problem by leading experts in the field. The selected topics range from protein chirality and its relevance to protein ageing, protein aggregation and neurodegeneration, entropy production associated with chiral symmetry breaking in closed systems, chiral oscillations in polymerization models involving higher-order oligomers, the mirror symmetry breaking in liquids and its implications for the development of homochirality in abiogenesis, the role of chirality in the chemical sciences, and some philosophical implications of chirality.
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institution Directory of Open Access Books
language eng
publishDate 2022
publishDateRange 2022
publishDateSort 2022
publisher MDPI - Multidisciplinary Digital Publishing Institute
publisherStr MDPI - Multidisciplinary Digital Publishing Institute
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spelling doab-20.500.12854ir-763792024-03-27T16:34:29Z Asymmetry in Biological Homochirality Hochberg, David biochirality post-translational modifications protein folding protein aggregation spontaneous chemical reactions neurodegeneration non-equilibrium phase transitions chiral symmetry breaking entropy production closed systems nonequilibrium dissipative structures mirror symmetry breaking biological chirality liquid crystals proto-RNA networks compartmentalization chiral liquids cubic phases prebiotic chemistry chirality amplification helical self-assembly chiral oscillations spontaneous mirror symmetry breaking origin of homochirality absolute asymmetric synthesis biological homochirality chemical abiotic evolution chirality origin of life dissipative reaction systems thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general Chirality, or handedness, is a fundamental physical characteristic, which spans the length scales ranging from elementary particles to the chiral asymmetry of spiral galaxies. The way in which chirality in chemistry, or molecular handedness, may have emerged in a primitive terrestrial environment, and how it can be triggered, amplified, and transferred, are deeply challenging problems rooted in both fundamental scientific interests and the technological potentials for science and society. Chirality constitutes a unifying feature of the living world and is a prime driving force for molecular selection and genetic evolution in biology. In this book, we offer a selection of five distinct approaches to this problem by leading experts in the field. The selected topics range from protein chirality and its relevance to protein ageing, protein aggregation and neurodegeneration, entropy production associated with chiral symmetry breaking in closed systems, chiral oscillations in polymerization models involving higher-order oligomers, the mirror symmetry breaking in liquids and its implications for the development of homochirality in abiogenesis, the role of chirality in the chemical sciences, and some philosophical implications of chirality. 2022-01-11T13:30:22Z 2022-01-11T13:30:22Z 2021 book ONIX_20220111_9783036504421_115 9783036504421 9783036504438 https://directory.doabooks.org/handle/20.500.12854/76379 eng image/jpeg Attribution 4.0 International https://mdpi.com/books/pdfview/book/3804 https://mdpi.com/books/pdfview/book/3804 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-0442-1 10.3390/books978-3-0365-0442-1 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036504421 9783036504438 102 Basel, Switzerland open access
spellingShingle biochirality
post-translational modifications
protein folding
protein aggregation
spontaneous chemical reactions
neurodegeneration
non-equilibrium phase transitions
chiral symmetry breaking
entropy production
closed systems
nonequilibrium
dissipative structures
mirror symmetry breaking
biological chirality
liquid crystals
proto-RNA
networks
compartmentalization
chiral liquids
cubic phases
prebiotic chemistry
chirality amplification
helical self-assembly
chiral oscillations
spontaneous mirror symmetry breaking
origin of homochirality
absolute asymmetric synthesis
biological homochirality
chemical abiotic evolution
chirality
origin of life
dissipative reaction systems
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
Asymmetry in Biological Homochirality
title Asymmetry in Biological Homochirality
title_full Asymmetry in Biological Homochirality
title_fullStr Asymmetry in Biological Homochirality
title_full_unstemmed Asymmetry in Biological Homochirality
title_short Asymmetry in Biological Homochirality
title_sort asymmetry in biological homochirality
topic biochirality
post-translational modifications
protein folding
protein aggregation
spontaneous chemical reactions
neurodegeneration
non-equilibrium phase transitions
chiral symmetry breaking
entropy production
closed systems
nonequilibrium
dissipative structures
mirror symmetry breaking
biological chirality
liquid crystals
proto-RNA
networks
compartmentalization
chiral liquids
cubic phases
prebiotic chemistry
chirality amplification
helical self-assembly
chiral oscillations
spontaneous mirror symmetry breaking
origin of homochirality
absolute asymmetric synthesis
biological homochirality
chemical abiotic evolution
chirality
origin of life
dissipative reaction systems
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
topic_facet biochirality
post-translational modifications
protein folding
protein aggregation
spontaneous chemical reactions
neurodegeneration
non-equilibrium phase transitions
chiral symmetry breaking
entropy production
closed systems
nonequilibrium
dissipative structures
mirror symmetry breaking
biological chirality
liquid crystals
proto-RNA
networks
compartmentalization
chiral liquids
cubic phases
prebiotic chemistry
chirality amplification
helical self-assembly
chiral oscillations
spontaneous mirror symmetry breaking
origin of homochirality
absolute asymmetric synthesis
biological homochirality
chemical abiotic evolution
chirality
origin of life
dissipative reaction systems
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
url ONIX_20220111_9783036504421_115