New Trends in Asymmetric Catalysis
The synthesis of enantiopure organic compounds is a key issue for several applications in pharmacology, food chemistry, agricultural chemistry, perfumery, materials science and other industrial sectors. Nowadays, asymmetric catalysis is undoubtedly the most important tool to achieve this goal. This...
-д хадгалсан:
| Формат: | Online |
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| Хэл сонгох: | англи |
| Хэвлэсэн: |
MDPI - Multidisciplinary Digital Publishing Institute
2022
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| Нөхцлүүд: | |
| Онлайн хандалт: | ONIX_20220111_9783036509723_205 |
| Шошгууд: |
Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!
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| _version_ | 1869519248892624896 |
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| collection | Directory of Open Access Books |
| description | The synthesis of enantiopure organic compounds is a key issue for several applications in pharmacology, food chemistry, agricultural chemistry, perfumery, materials science and other industrial sectors. Nowadays, asymmetric catalysis is undoubtedly the most important tool to achieve this goal. This technology, in fact, enables the production of large amounts of enantiomerically enriched compounds, employing relatively small quantities of chiral enantiopure catalysts, which is exactly what is accomplished by enzymes in nature. Since the pioneering works of Noyori, Knowles and Sharpless, which later earned them the Nobel Prize in Chemistry, asymmetric catalysis has experienced a rapid and relentless development in the last fifty years. The tremendous expansion of enantioselective transformations, the design of novel and more efficient organometallic and organic catalysts, the development of sophisticated bioreactors and cell factories, are just some of the elements responsible for such growth. However, new challenges of asymmetric catalysis are devoted to enhancing the process’s sustainability, by the introduction of recyclable and low-cost catalysts, and the use of renewable starting materials and energy source. This book provides an overview of some of these development directions and comprises a collection of review papers and a research article authored by renowned researchers actively involved in this field. The topics covered by the review papers are photoredox-catalyzed reactions of imines, asymmetric catalytic electrosynthesis, cooperative catalysis of chiral N-heterocyclic carbenes and Lewis acid, and asymmetric ring-opening reactions of epoxides catalyzed by metal–salen complexes. The research article presents a proline-catalyzed aldol reaction in water–methanol solvent mixture. |
| format | Online |
| id | doab-20.500.12854ir-76469 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2022 |
| publishDateRange | 2022 |
| publishDateSort | 2022 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-764692024-03-27T16:34:30Z New Trends in Asymmetric Catalysis Della Sala, Giorgio Schettini, Rosaria N-heterocyclic carbenes (NHC) Lewis acid cooperative catalysis asymmetric synthesis umpolung amines imines photoredox catalysis radical additions radical–radical couplings stereoselectivity umpolung chemistry visible light proline organocatalysis asymmetric aldol reaction methanol/water mixtures sustainability asymmetric catalysis salen complexes ring-opening epoxide kinetic resolution organic electrosynthesis electrochemistry enantioselectivity transition-metal catalysis n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general The synthesis of enantiopure organic compounds is a key issue for several applications in pharmacology, food chemistry, agricultural chemistry, perfumery, materials science and other industrial sectors. Nowadays, asymmetric catalysis is undoubtedly the most important tool to achieve this goal. This technology, in fact, enables the production of large amounts of enantiomerically enriched compounds, employing relatively small quantities of chiral enantiopure catalysts, which is exactly what is accomplished by enzymes in nature. Since the pioneering works of Noyori, Knowles and Sharpless, which later earned them the Nobel Prize in Chemistry, asymmetric catalysis has experienced a rapid and relentless development in the last fifty years. The tremendous expansion of enantioselective transformations, the design of novel and more efficient organometallic and organic catalysts, the development of sophisticated bioreactors and cell factories, are just some of the elements responsible for such growth. However, new challenges of asymmetric catalysis are devoted to enhancing the process’s sustainability, by the introduction of recyclable and low-cost catalysts, and the use of renewable starting materials and energy source. This book provides an overview of some of these development directions and comprises a collection of review papers and a research article authored by renowned researchers actively involved in this field. The topics covered by the review papers are photoredox-catalyzed reactions of imines, asymmetric catalytic electrosynthesis, cooperative catalysis of chiral N-heterocyclic carbenes and Lewis acid, and asymmetric ring-opening reactions of epoxides catalyzed by metal–salen complexes. The research article presents a proline-catalyzed aldol reaction in water–methanol solvent mixture. 2022-01-11T13:32:47Z 2022-01-11T13:32:47Z 2021 book ONIX_20220111_9783036509723_205 9783036509723 9783036509730 https://directory.doabooks.org/handle/20.500.12854/76469 eng image/jpeg Attribution 4.0 International https://mdpi.com/books/pdfview/book/3905 https://mdpi.com/books/pdfview/book/3905 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-0973-0 10.3390/books978-3-0365-0973-0 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036509723 9783036509730 172 Basel, Switzerland open access |
| spellingShingle | N-heterocyclic carbenes (NHC) Lewis acid cooperative catalysis asymmetric synthesis umpolung amines imines photoredox catalysis radical additions radical–radical couplings stereoselectivity umpolung chemistry visible light proline organocatalysis asymmetric aldol reaction methanol/water mixtures sustainability asymmetric catalysis salen complexes ring-opening epoxide kinetic resolution organic electrosynthesis electrochemistry enantioselectivity transition-metal catalysis n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general New Trends in Asymmetric Catalysis |
| title | New Trends in Asymmetric Catalysis |
| title_full | New Trends in Asymmetric Catalysis |
| title_fullStr | New Trends in Asymmetric Catalysis |
| title_full_unstemmed | New Trends in Asymmetric Catalysis |
| title_short | New Trends in Asymmetric Catalysis |
| title_sort | new trends in asymmetric catalysis |
| topic | N-heterocyclic carbenes (NHC) Lewis acid cooperative catalysis asymmetric synthesis umpolung amines imines photoredox catalysis radical additions radical–radical couplings stereoselectivity umpolung chemistry visible light proline organocatalysis asymmetric aldol reaction methanol/water mixtures sustainability asymmetric catalysis salen complexes ring-opening epoxide kinetic resolution organic electrosynthesis electrochemistry enantioselectivity transition-metal catalysis n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general |
| topic_facet | N-heterocyclic carbenes (NHC) Lewis acid cooperative catalysis asymmetric synthesis umpolung amines imines photoredox catalysis radical additions radical–radical couplings stereoselectivity umpolung chemistry visible light proline organocatalysis asymmetric aldol reaction methanol/water mixtures sustainability asymmetric catalysis salen complexes ring-opening epoxide kinetic resolution organic electrosynthesis electrochemistry enantioselectivity transition-metal catalysis n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general |
| url | ONIX_20220111_9783036509723_205 |