Recent Developments in Annexin Biology
Discovered over 40 years ago, the annexin proteins were found to be a structurally conserved subgroup of Ca2+-binding proteins. While the initial research on annexins focused on their signature feature of Ca2+-dependent binding to membranes, over the years, the biennial “Annexin” conference series h...
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| Materiálatiipa: | Online |
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| Giella: | eaŋgalasgiella |
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MDPI - Multidisciplinary Digital Publishing Institute
2022
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| Liŋkkat: | ONIX_20220111_9783036501987_235 |
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| collection | Directory of Open Access Books |
| description | Discovered over 40 years ago, the annexin proteins were found to be a structurally conserved subgroup of Ca2+-binding proteins. While the initial research on annexins focused on their signature feature of Ca2+-dependent binding to membranes, over the years, the biennial “Annexin” conference series has highlighted additional diversity in the functions attributed to the annexin family of proteins. The roles of these proteins now extend from basic science to biomedical research, and are being translated into clinical settings. Research on annexins involves a global network of researchers and the 10th biennial Annexin conference brought together over 80 researchers from ten European countries, USA, Brazil, Singapore, Japan, and Australia for 3 days in September 2019. In this conference, the discussions focused on two distinct themes — the role of annexins in cellular organization and health and disease. The articles published in this Special Issue cover these two main themes discussed at the conference, offering a glimpse into some of the notable findings in the field of annexin biology |
| format | Online |
| id | doab-20.500.12854ir-76499 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2022 |
| publishDateRange | 2022 |
| publishDateSort | 2022 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-764992024-03-27T16:34:40Z Recent Developments in Annexin Biology Jaiswal, Jyoti K. Gerke, Volker Rescher, Ursula Kim Lim, Lina Hsiu inflammation nigericin pyroptosis mass spectrometry lipidomics anxA2 Birbeck granules Langerhans cell A2t annexin plasma membrane repair membrane curvature membrane curvature sensing membrane shaping interdisciplinary research cell rupture membrane damage bias analysis G protein-coupled receptor (GPCR) formyl peptide receptor 1 danger-associated molecular pattern (DAMP) pathogen-associated molecular pattern (PAMP) annexin A1 peptide Ac2-26 cholesterol AnxA6 chaperone-mediated autophagy endolysosomes NPC1 Lamp2A annexin A2 microdomain cross-linker quartz crystal microbalance with dissipation monitoring (QCM-D) mucin-1 claudin-1 zona occludens ERK1/2 pathway angiogenesis F-actin polymerization BeWo spheroids Ishikawa cells influenza RNA-sequencing transcriptomics autophagy Annexin-A1 infection adherens junction macroautophagy breast cancer estrogen receptor negative Annexin A2 metastasis annexin-A6 membrane repair human skeletal muscle cap subdomain fluorescence electron microscopy CLEM annexin A6 RasGRF2 EGFR cell growth cell motility acquired resistance tyrosine kinase inhibitors muscle injury plasma membrane vesicle muscular dystrophy annexinA2 egress exocytosis chromaffin cells thrombosis Annexin A1 formyl peptide receptors sickle cell disease sepsis Annexin membrane injury virus lipid cancer thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general Discovered over 40 years ago, the annexin proteins were found to be a structurally conserved subgroup of Ca2+-binding proteins. While the initial research on annexins focused on their signature feature of Ca2+-dependent binding to membranes, over the years, the biennial “Annexin” conference series has highlighted additional diversity in the functions attributed to the annexin family of proteins. The roles of these proteins now extend from basic science to biomedical research, and are being translated into clinical settings. Research on annexins involves a global network of researchers and the 10th biennial Annexin conference brought together over 80 researchers from ten European countries, USA, Brazil, Singapore, Japan, and Australia for 3 days in September 2019. In this conference, the discussions focused on two distinct themes — the role of annexins in cellular organization and health and disease. The articles published in this Special Issue cover these two main themes discussed at the conference, offering a glimpse into some of the notable findings in the field of annexin biology 2022-01-11T13:33:37Z 2022-01-11T13:33:37Z 2021 book ONIX_20220111_9783036501987_235 9783036501987 9783036501994 https://directory.doabooks.org/handle/20.500.12854/76499 eng image/jpeg Attribution 4.0 International https://mdpi.com/books/pdfview/book/3945 https://mdpi.com/books/pdfview/book/3945 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-0199-4 10.3390/books978-3-0365-0199-4 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036501987 9783036501994 266 Basel, Switzerland open access |
| spellingShingle | inflammation nigericin pyroptosis mass spectrometry lipidomics anxA2 Birbeck granules Langerhans cell A2t annexin plasma membrane repair membrane curvature membrane curvature sensing membrane shaping interdisciplinary research cell rupture membrane damage bias analysis G protein-coupled receptor (GPCR) formyl peptide receptor 1 danger-associated molecular pattern (DAMP) pathogen-associated molecular pattern (PAMP) annexin A1 peptide Ac2-26 cholesterol AnxA6 chaperone-mediated autophagy endolysosomes NPC1 Lamp2A annexin A2 microdomain cross-linker quartz crystal microbalance with dissipation monitoring (QCM-D) mucin-1 claudin-1 zona occludens ERK1/2 pathway angiogenesis F-actin polymerization BeWo spheroids Ishikawa cells influenza RNA-sequencing transcriptomics autophagy Annexin-A1 infection adherens junction macroautophagy breast cancer estrogen receptor negative Annexin A2 metastasis annexin-A6 membrane repair human skeletal muscle cap subdomain fluorescence electron microscopy CLEM annexin A6 RasGRF2 EGFR cell growth cell motility acquired resistance tyrosine kinase inhibitors muscle injury plasma membrane vesicle muscular dystrophy annexinA2 egress exocytosis chromaffin cells thrombosis Annexin A1 formyl peptide receptors sickle cell disease sepsis Annexin membrane injury virus lipid cancer thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general Recent Developments in Annexin Biology |
| title | Recent Developments in Annexin Biology |
| title_full | Recent Developments in Annexin Biology |
| title_fullStr | Recent Developments in Annexin Biology |
| title_full_unstemmed | Recent Developments in Annexin Biology |
| title_short | Recent Developments in Annexin Biology |
| title_sort | recent developments in annexin biology |
| topic | inflammation nigericin pyroptosis mass spectrometry lipidomics anxA2 Birbeck granules Langerhans cell A2t annexin plasma membrane repair membrane curvature membrane curvature sensing membrane shaping interdisciplinary research cell rupture membrane damage bias analysis G protein-coupled receptor (GPCR) formyl peptide receptor 1 danger-associated molecular pattern (DAMP) pathogen-associated molecular pattern (PAMP) annexin A1 peptide Ac2-26 cholesterol AnxA6 chaperone-mediated autophagy endolysosomes NPC1 Lamp2A annexin A2 microdomain cross-linker quartz crystal microbalance with dissipation monitoring (QCM-D) mucin-1 claudin-1 zona occludens ERK1/2 pathway angiogenesis F-actin polymerization BeWo spheroids Ishikawa cells influenza RNA-sequencing transcriptomics autophagy Annexin-A1 infection adherens junction macroautophagy breast cancer estrogen receptor negative Annexin A2 metastasis annexin-A6 membrane repair human skeletal muscle cap subdomain fluorescence electron microscopy CLEM annexin A6 RasGRF2 EGFR cell growth cell motility acquired resistance tyrosine kinase inhibitors muscle injury plasma membrane vesicle muscular dystrophy annexinA2 egress exocytosis chromaffin cells thrombosis Annexin A1 formyl peptide receptors sickle cell disease sepsis Annexin membrane injury virus lipid cancer thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general |
| topic_facet | inflammation nigericin pyroptosis mass spectrometry lipidomics anxA2 Birbeck granules Langerhans cell A2t annexin plasma membrane repair membrane curvature membrane curvature sensing membrane shaping interdisciplinary research cell rupture membrane damage bias analysis G protein-coupled receptor (GPCR) formyl peptide receptor 1 danger-associated molecular pattern (DAMP) pathogen-associated molecular pattern (PAMP) annexin A1 peptide Ac2-26 cholesterol AnxA6 chaperone-mediated autophagy endolysosomes NPC1 Lamp2A annexin A2 microdomain cross-linker quartz crystal microbalance with dissipation monitoring (QCM-D) mucin-1 claudin-1 zona occludens ERK1/2 pathway angiogenesis F-actin polymerization BeWo spheroids Ishikawa cells influenza RNA-sequencing transcriptomics autophagy Annexin-A1 infection adherens junction macroautophagy breast cancer estrogen receptor negative Annexin A2 metastasis annexin-A6 membrane repair human skeletal muscle cap subdomain fluorescence electron microscopy CLEM annexin A6 RasGRF2 EGFR cell growth cell motility acquired resistance tyrosine kinase inhibitors muscle injury plasma membrane vesicle muscular dystrophy annexinA2 egress exocytosis chromaffin cells thrombosis Annexin A1 formyl peptide receptors sickle cell disease sepsis Annexin membrane injury virus lipid cancer thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general |
| url | ONIX_20220111_9783036501987_235 |