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Cytochromes P450: Drug Metabolism, Bioactivation and Biodiversity 2.0

This book, "Cytochromes P450: Drug Metabolism, Bioactivation and Biodiversity", presents five papers on human cytochrome P450 (CYP) and P450 reductase, three reviews on the role of CYPs in humans and their use as biomarkers, six papers on CYPs in microorganisms, and one study on CYP in insects. The...

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Format: Online
Language:English
Published: MDPI - Multidisciplinary Digital Publishing Institute 2022
Subjects:
Antibiotics
Bacillus
biosynthetic gene clusters
comparative analysis
cytochrome P450 monooxygenase
Mycobacterium
P450 diversity percentage
P450 profiling
secondary metabolites
NADPH-cytochrome P450 reductase (CPR)
microsomal cytochrome P450 (CYP)
Cytochrome b5 (CYB5)
protein dynamics
electron-transfer (ET)
protein–protein interaction
cytochromes P450
CYP3A4
active site access channels
cavities boundaries
minimal cost paths
CYP139A1
genome data mining
host metabolism
Mycobacterium tuberculosis
polyketides
tuberculosis
cryptococcus
cryptococcus neoformans
CYP51
fungal pathogens
genome data-mining
human pathogens
CYP diversity analysis
tremellomycetes
trichosporon
mechanism-based inhibitor
crystal structure
CYP4 genes
genetic polymorphisms
20-HETE
fatty acid
arachidonic acid
SNPs
molecular functionality
metabolism
lamellar ichthyosis
Bietti’s crystalline dystrophy
cytochrome P450
isoform
membrane protein
protein-membrane interactions
enzyme substrate specificity
mutagenesis
molecular dynamics simulation
Sogatella furcifera
sulfoxaflor
transcriptome
RNA interference
CYP2C8
polymorphisms
reactive oxygen species
paclitaxel
cytochrome P450 reductase
electron transfer
extracellular vesicles
exosomes
extrahepatic tissues
plasma
circulatory CYPs
CYP450
drug metabolism
precision Cardio-Oncology
precision medicine
systems medicine
cytochromes P450 monooxygenases
Cyanobacteria
gene-cluster diversity percentage
mathematical formula
phylogenetic analysis
Streptomyces
cytochrome P450 monooxygenases
terpenes
P450 blooming
non-ribosomal peptides
cytochrome P450 monooxygenenases
CYP128A1
Mycobacterium tuberculosis H37Rv
molecular dynamic simulations
azole drugs
menaquinone
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
Online Access:ONIX_20220111_9783036502564_248
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