Recent Developments in Cancer Systems Biology
This ebook includes original research articles and reviews to update readers on the state of the art systems approach to not only discover novel diagnostic and prognostic biomarkers for several cancer types, but also evaluate methodologies to map out important genomic signatures. In addition, therap...
Gardado en:
| Formato: | Online |
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| Idioma: | inglés |
| Publicado: |
MDPI - Multidisciplinary Digital Publishing Institute
2022
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| Subjects: | |
| Acceso en liña: | ONIX_20220111_9783036514727_455 |
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| _version_ | 1869528962075459584 |
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| collection | Directory of Open Access Books |
| description | This ebook includes original research articles and reviews to update readers on the state of the art systems approach to not only discover novel diagnostic and prognostic biomarkers for several cancer types, but also evaluate methodologies to map out important genomic signatures. In addition, therapeutic targets and drug repurposing have been emphasized for a variety of cancer types. In particular, new and established researchers who desire to learn about cancer systems biology and why it is possibly the leading front to a personalized medicine approach will enjoy reading this book. |
| format | Online |
| id | doab-20.500.12854ir-76720 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2022 |
| publishDateRange | 2022 |
| publishDateSort | 2022 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-767202024-03-31T13:10:02Z Recent Developments in Cancer Systems Biology Sinha, Raghu Arga, Kazim Yalcin Sestrin2 lung cancer knockdown cancer progression bioinformatics patient survival lung adenocarcinoma circulating miR-1246 glycosaminoglycan binding prognosis PI3K–Akt signaling pathways TargetScan UBE2C cancer systems biology experimental model systems next-generation sequencing single-cell sequencing patient-derived xenografts patient-derived organoids triple-negative breast cancer personalized medicine computational methods drug repurposing clinical trials cancer stem cells ETS Elk-1 stem cell microarray brain-tumor-initiating cell (BTIC) pancreatic cancer systems biology omics biomarker genomics transcriptomics proteomics metabolomics glycomics metagenomics Ets PEA3 Ets-1 glioma optical genome mapping solid tumors cancer genomics breast ovarian cancer TCGA non-small-cell lung cancer lung adenocarcinoma (LUAD) lung squamous cell carcinoma (LUSC) differential expression SNV CNV risk group signature survival renal cancers protein interactome diagnostic biomarker prognostic biomarker virtual screening docking acute myeloid leukemia Boolean model drug resistance network n/a thema EDItEUR::M Medicine and Nursing This ebook includes original research articles and reviews to update readers on the state of the art systems approach to not only discover novel diagnostic and prognostic biomarkers for several cancer types, but also evaluate methodologies to map out important genomic signatures. In addition, therapeutic targets and drug repurposing have been emphasized for a variety of cancer types. In particular, new and established researchers who desire to learn about cancer systems biology and why it is possibly the leading front to a personalized medicine approach will enjoy reading this book. 2022-01-11T13:40:05Z 2022-01-11T13:40:05Z 2021 book ONIX_20220111_9783036514727_455 9783036514727 9783036514710 https://directory.doabooks.org/handle/20.500.12854/76720 eng image/jpeg Attribution 4.0 International https://mdpi.com/books/pdfview/book/4169 https://mdpi.com/books/pdfview/book/4169 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-1471-0 10.3390/books978-3-0365-1471-0 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036514727 9783036514710 272 Basel, Switzerland open access |
| spellingShingle | Sestrin2 lung cancer knockdown cancer progression bioinformatics patient survival lung adenocarcinoma circulating miR-1246 glycosaminoglycan binding prognosis PI3K–Akt signaling pathways TargetScan UBE2C cancer systems biology experimental model systems next-generation sequencing single-cell sequencing patient-derived xenografts patient-derived organoids triple-negative breast cancer personalized medicine computational methods drug repurposing clinical trials cancer stem cells ETS Elk-1 stem cell microarray brain-tumor-initiating cell (BTIC) pancreatic cancer systems biology omics biomarker genomics transcriptomics proteomics metabolomics glycomics metagenomics Ets PEA3 Ets-1 glioma optical genome mapping solid tumors cancer genomics breast ovarian cancer TCGA non-small-cell lung cancer lung adenocarcinoma (LUAD) lung squamous cell carcinoma (LUSC) differential expression SNV CNV risk group signature survival renal cancers protein interactome diagnostic biomarker prognostic biomarker virtual screening docking acute myeloid leukemia Boolean model drug resistance network n/a thema EDItEUR::M Medicine and Nursing Recent Developments in Cancer Systems Biology |
| title | Recent Developments in Cancer Systems Biology |
| title_full | Recent Developments in Cancer Systems Biology |
| title_fullStr | Recent Developments in Cancer Systems Biology |
| title_full_unstemmed | Recent Developments in Cancer Systems Biology |
| title_short | Recent Developments in Cancer Systems Biology |
| title_sort | recent developments in cancer systems biology |
| topic | Sestrin2 lung cancer knockdown cancer progression bioinformatics patient survival lung adenocarcinoma circulating miR-1246 glycosaminoglycan binding prognosis PI3K–Akt signaling pathways TargetScan UBE2C cancer systems biology experimental model systems next-generation sequencing single-cell sequencing patient-derived xenografts patient-derived organoids triple-negative breast cancer personalized medicine computational methods drug repurposing clinical trials cancer stem cells ETS Elk-1 stem cell microarray brain-tumor-initiating cell (BTIC) pancreatic cancer systems biology omics biomarker genomics transcriptomics proteomics metabolomics glycomics metagenomics Ets PEA3 Ets-1 glioma optical genome mapping solid tumors cancer genomics breast ovarian cancer TCGA non-small-cell lung cancer lung adenocarcinoma (LUAD) lung squamous cell carcinoma (LUSC) differential expression SNV CNV risk group signature survival renal cancers protein interactome diagnostic biomarker prognostic biomarker virtual screening docking acute myeloid leukemia Boolean model drug resistance network n/a thema EDItEUR::M Medicine and Nursing |
| topic_facet | Sestrin2 lung cancer knockdown cancer progression bioinformatics patient survival lung adenocarcinoma circulating miR-1246 glycosaminoglycan binding prognosis PI3K–Akt signaling pathways TargetScan UBE2C cancer systems biology experimental model systems next-generation sequencing single-cell sequencing patient-derived xenografts patient-derived organoids triple-negative breast cancer personalized medicine computational methods drug repurposing clinical trials cancer stem cells ETS Elk-1 stem cell microarray brain-tumor-initiating cell (BTIC) pancreatic cancer systems biology omics biomarker genomics transcriptomics proteomics metabolomics glycomics metagenomics Ets PEA3 Ets-1 glioma optical genome mapping solid tumors cancer genomics breast ovarian cancer TCGA non-small-cell lung cancer lung adenocarcinoma (LUAD) lung squamous cell carcinoma (LUSC) differential expression SNV CNV risk group signature survival renal cancers protein interactome diagnostic biomarker prognostic biomarker virtual screening docking acute myeloid leukemia Boolean model drug resistance network n/a thema EDItEUR::M Medicine and Nursing |
| url | ONIX_20220111_9783036514727_455 |