Crocus sativus L. Extract and Its Constituents: Chemistry, Pharmacology and Therapeutic Potential
Natural products or organic compounds isolated from natural sources as primary or secondary metabolites have inspired numerous drugs. It is not an overstatement that the majority of medicines in clinics, even in the 21st century, have been derived from natural resources despite the decline of indust...
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| Μορφή: | Online |
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| Γλώσσα: | Αγγλικά |
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MDPI - Multidisciplinary Digital Publishing Institute
2022
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| Θέματα: | |
| Διαθέσιμο Online: | ONIX_20220111_9783036518060_511 |
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| _version_ | 1869524332838912000 |
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| collection | Directory of Open Access Books |
| description | Natural products or organic compounds isolated from natural sources as primary or secondary metabolites have inspired numerous drugs. It is not an overstatement that the majority of medicines in clinics, even in the 21st century, have been derived from natural resources despite the decline of industry research into natural products due to a variety of drawbacks. Saffron crocus, considered to be the most valuable spice by weight, and its bioactive constituents, have been studied for the treatment of a wide range of pathologies, including neuropsychiatric and neurodegenerative disorders, cancer, diabetes, and even cardiovascular diseases. In this book on the chemistry, pharmacology, and therapeutic potential of Crocus sativus L. extract and its constituents, we aimed to assess new advances in the understanding of the therapeutic action of saffron and its constituents in targeting different pathologies. In this context, eight original research articles covering recent advances in the therapeutic actions of saffron and its ingredients in different diseases are reported. Two studies reporting novel methods regarding the bioanalysis of saffron extracts have been included. The collection is completed with two very interesting reviews reporting advances in the fields of schizophrenia and cancer. In conclusion, in this book, we are delighted to have received several contributions that we hope will provide new and interesting information for the scientific community on the chemistry, pharmacology, and therapeutic potential of Crocus sativus L. extract and its constituents. |
| format | Online |
| id | doab-20.500.12854ir-76776 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2022 |
| publishDateRange | 2022 |
| publishDateSort | 2022 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-767762024-03-31T13:10:47Z Crocus sativus L. Extract and Its Constituents: Chemistry, Pharmacology and Therapeutic Potential Pitsikas, Nikolaos Dimas, Konstantinos saffron affron® depression anxiety antioxidant crocins glucose β-pancreatic cells insulin pck1 neuroprotective activity P2X7 receptor fraction flumazenil rat Crocus sativus cancer anticancer activity chemoprevention clinical trials patents anesthetic ketamine memory Crocus sativus L. schizophrenia crocetin pubertal testis X-rays radiotherapy fertility preservation SIRT1 HuR oxidative stress autophagy crocin picrocrocin safranal dietary supplement nutraceutical Crocus sativus L. (Iridaceae) reversed-phase UPLC metabolomics HR MS inflammatory bowel disease gut microbiota colitis cytokines colorectal cancer HCT116 MLH1 MSH3 DNA damage and repair apoptosis n/a thema EDItEUR::M Medicine and Nursing Natural products or organic compounds isolated from natural sources as primary or secondary metabolites have inspired numerous drugs. It is not an overstatement that the majority of medicines in clinics, even in the 21st century, have been derived from natural resources despite the decline of industry research into natural products due to a variety of drawbacks. Saffron crocus, considered to be the most valuable spice by weight, and its bioactive constituents, have been studied for the treatment of a wide range of pathologies, including neuropsychiatric and neurodegenerative disorders, cancer, diabetes, and even cardiovascular diseases. In this book on the chemistry, pharmacology, and therapeutic potential of Crocus sativus L. extract and its constituents, we aimed to assess new advances in the understanding of the therapeutic action of saffron and its constituents in targeting different pathologies. In this context, eight original research articles covering recent advances in the therapeutic actions of saffron and its ingredients in different diseases are reported. Two studies reporting novel methods regarding the bioanalysis of saffron extracts have been included. The collection is completed with two very interesting reviews reporting advances in the fields of schizophrenia and cancer. In conclusion, in this book, we are delighted to have received several contributions that we hope will provide new and interesting information for the scientific community on the chemistry, pharmacology, and therapeutic potential of Crocus sativus L. extract and its constituents. 2022-01-11T13:41:56Z 2022-01-11T13:41:56Z 2021 book ONIX_20220111_9783036518060_511 9783036518060 9783036518053 https://directory.doabooks.org/handle/20.500.12854/76776 eng image/jpeg Attribution 4.0 International https://mdpi.com/books/pdfview/book/4225 https://mdpi.com/books/pdfview/book/4225 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-1805-3 10.3390/books978-3-0365-1805-3 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036518060 9783036518053 171 Basel, Switzerland open access |
| spellingShingle | saffron affron® depression anxiety antioxidant crocins glucose β-pancreatic cells insulin pck1 neuroprotective activity P2X7 receptor fraction flumazenil rat Crocus sativus cancer anticancer activity chemoprevention clinical trials patents anesthetic ketamine memory Crocus sativus L. schizophrenia crocetin pubertal testis X-rays radiotherapy fertility preservation SIRT1 HuR oxidative stress autophagy crocin picrocrocin safranal dietary supplement nutraceutical Crocus sativus L. (Iridaceae) reversed-phase UPLC metabolomics HR MS inflammatory bowel disease gut microbiota colitis cytokines colorectal cancer HCT116 MLH1 MSH3 DNA damage and repair apoptosis n/a thema EDItEUR::M Medicine and Nursing Crocus sativus L. Extract and Its Constituents: Chemistry, Pharmacology and Therapeutic Potential |
| title | Crocus sativus L. Extract and Its Constituents: Chemistry, Pharmacology and Therapeutic Potential |
| title_full | Crocus sativus L. Extract and Its Constituents: Chemistry, Pharmacology and Therapeutic Potential |
| title_fullStr | Crocus sativus L. Extract and Its Constituents: Chemistry, Pharmacology and Therapeutic Potential |
| title_full_unstemmed | Crocus sativus L. Extract and Its Constituents: Chemistry, Pharmacology and Therapeutic Potential |
| title_short | Crocus sativus L. Extract and Its Constituents: Chemistry, Pharmacology and Therapeutic Potential |
| title_sort | crocus sativus l extract and its constituents chemistry pharmacology and therapeutic potential |
| topic | saffron affron® depression anxiety antioxidant crocins glucose β-pancreatic cells insulin pck1 neuroprotective activity P2X7 receptor fraction flumazenil rat Crocus sativus cancer anticancer activity chemoprevention clinical trials patents anesthetic ketamine memory Crocus sativus L. schizophrenia crocetin pubertal testis X-rays radiotherapy fertility preservation SIRT1 HuR oxidative stress autophagy crocin picrocrocin safranal dietary supplement nutraceutical Crocus sativus L. (Iridaceae) reversed-phase UPLC metabolomics HR MS inflammatory bowel disease gut microbiota colitis cytokines colorectal cancer HCT116 MLH1 MSH3 DNA damage and repair apoptosis n/a thema EDItEUR::M Medicine and Nursing |
| topic_facet | saffron affron® depression anxiety antioxidant crocins glucose β-pancreatic cells insulin pck1 neuroprotective activity P2X7 receptor fraction flumazenil rat Crocus sativus cancer anticancer activity chemoprevention clinical trials patents anesthetic ketamine memory Crocus sativus L. schizophrenia crocetin pubertal testis X-rays radiotherapy fertility preservation SIRT1 HuR oxidative stress autophagy crocin picrocrocin safranal dietary supplement nutraceutical Crocus sativus L. (Iridaceae) reversed-phase UPLC metabolomics HR MS inflammatory bowel disease gut microbiota colitis cytokines colorectal cancer HCT116 MLH1 MSH3 DNA damage and repair apoptosis n/a thema EDItEUR::M Medicine and Nursing |
| url | ONIX_20220111_9783036518060_511 |