Marine Carbohydrate-Based Compounds with Medicinal Properties
The marine environment is considered one of the most important sources of natural bioactive compounds with extremely rich biodiversity. Marine glycans are remarkable molecules, playing a determinant role in biological processes. Marine сarbohydrate-containing substances have drawn increasing attenti...
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| التنسيق: | Online |
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| اللغة: | الإنجليزية |
| منشور في: |
MDPI - Multidisciplinary Digital Publishing Institute
2022
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| الموضوعات: | |
| الوصول للمادة أونلاين: | ONIX_20220111_9783036520919_754 |
| الوسوم: |
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| _version_ | 1869527209149988864 |
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| collection | Directory of Open Access Books |
| description | The marine environment is considered one of the most important sources of natural bioactive compounds with extremely rich biodiversity. Marine glycans are remarkable molecules, playing a determinant role in biological processes. Marine сarbohydrate-containing substances have drawn increasing attention in the field of biomedicine for their various biological activities, such as antitumor, antivirus, hypoglycemic, immunomodulatory, and anticoagulant. These compounds obtained from marine sources, such as algae, microbes, and animals, are usually biodegradable and biocompatible, and exhibit biological properties that contribute to the discovery of a wide range of new bioactive substances with special pharmacological properties of interest to medicine. Carbohydrate-based compounds include glycans, glycoproteins, proteoglycans, glycolipids, and low-molecular and complex glycosides of differential origin. Many of the polysaccharides allow for loading lower drug dosages, which may lead to a drastic reduction of the side effects caused by the drugs. In addition, the structure of polysaccharides can be relatively easily modified in order to synthesize derivatives with desirable characteristics for drug delivery. Complexes on the basis of carbohydrates are often prepared to improve their functional properties. In this Special Issue, we seek to contribute to the discussion of various aspects of marine carbohydrate-containing compounds and provide a unique platform for a new concept for their use in medicine in order to continue to facilitate further research in this area. |
| format | Online |
| id | doab-20.500.12854ir-76922 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2022 |
| publishDateRange | 2022 |
| publishDateSort | 2022 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-769222024-03-31T13:09:51Z Marine Carbohydrate-Based Compounds with Medicinal Properties Yermak, Irina M. Davydova, Viktoria chitosan-gentamicin conjugate antimicrobial anti-inflammatory scald repair sulfated polysaccharides galactans green seaweed NMR immunostimulation inflammatory mediators carrageenan lipopolysaccharide macromolecular structure nonspecific resistance to lipopolysaccharide cytokines enteric infections salmonellosis glyceroglycolipid metabolism phosphate starvation transcriptome glyceroglycolipid homeostasis chitosan polyelectrolyte complex cytokine nitric oxide anti-inflammatory activity Ulva pertusa polysaccharides colitis antioxidant exopolysaccharide structure Vibrio alginolyticus Epidermist chitosan oligosaccharides inflammation cytokines intestine oxidative status oxidative stress Porphyridium marinum high pressure homogenizer antibacterial activity anti-biofilm activity anti-cancer activity alginate lyase cold-adapted exo/endo-type Alteromonas portus oligosaccharide antioxidant activity exopolysaccharides scandium theranostic cancer cell lines proliferation laminarin fucoidan gastrointestinal tract microbiome swine post-weaning antibiotic alternatives n/a thema EDItEUR::M Medicine and Nursing The marine environment is considered one of the most important sources of natural bioactive compounds with extremely rich biodiversity. Marine glycans are remarkable molecules, playing a determinant role in biological processes. Marine сarbohydrate-containing substances have drawn increasing attention in the field of biomedicine for their various biological activities, such as antitumor, antivirus, hypoglycemic, immunomodulatory, and anticoagulant. These compounds obtained from marine sources, such as algae, microbes, and animals, are usually biodegradable and biocompatible, and exhibit biological properties that contribute to the discovery of a wide range of new bioactive substances with special pharmacological properties of interest to medicine. Carbohydrate-based compounds include glycans, glycoproteins, proteoglycans, glycolipids, and low-molecular and complex glycosides of differential origin. Many of the polysaccharides allow for loading lower drug dosages, which may lead to a drastic reduction of the side effects caused by the drugs. In addition, the structure of polysaccharides can be relatively easily modified in order to synthesize derivatives with desirable characteristics for drug delivery. Complexes on the basis of carbohydrates are often prepared to improve their functional properties. In this Special Issue, we seek to contribute to the discussion of various aspects of marine carbohydrate-containing compounds and provide a unique platform for a new concept for their use in medicine in order to continue to facilitate further research in this area. 2022-01-11T13:46:33Z 2022-01-11T13:46:33Z 2021 book ONIX_20220111_9783036520919_754 9783036520919 9783036520926 https://directory.doabooks.org/handle/20.500.12854/76922 eng image/jpeg Attribution 4.0 International https://mdpi.com/books/pdfview/book/4513 https://mdpi.com/books/pdfview/book/4513 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-2092-6 10.3390/books978-3-0365-2092-6 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036520919 9783036520926 214 Basel, Switzerland open access |
| spellingShingle | chitosan-gentamicin conjugate antimicrobial anti-inflammatory scald repair sulfated polysaccharides galactans green seaweed NMR immunostimulation inflammatory mediators carrageenan lipopolysaccharide macromolecular structure nonspecific resistance to lipopolysaccharide cytokines enteric infections salmonellosis glyceroglycolipid metabolism phosphate starvation transcriptome glyceroglycolipid homeostasis chitosan polyelectrolyte complex cytokine nitric oxide anti-inflammatory activity Ulva pertusa polysaccharides colitis antioxidant exopolysaccharide structure Vibrio alginolyticus Epidermist chitosan oligosaccharides inflammation cytokines intestine oxidative status oxidative stress Porphyridium marinum high pressure homogenizer antibacterial activity anti-biofilm activity anti-cancer activity alginate lyase cold-adapted exo/endo-type Alteromonas portus oligosaccharide antioxidant activity exopolysaccharides scandium theranostic cancer cell lines proliferation laminarin fucoidan gastrointestinal tract microbiome swine post-weaning antibiotic alternatives n/a thema EDItEUR::M Medicine and Nursing Marine Carbohydrate-Based Compounds with Medicinal Properties |
| title | Marine Carbohydrate-Based Compounds with Medicinal Properties |
| title_full | Marine Carbohydrate-Based Compounds with Medicinal Properties |
| title_fullStr | Marine Carbohydrate-Based Compounds with Medicinal Properties |
| title_full_unstemmed | Marine Carbohydrate-Based Compounds with Medicinal Properties |
| title_short | Marine Carbohydrate-Based Compounds with Medicinal Properties |
| title_sort | marine carbohydrate based compounds with medicinal properties |
| topic | chitosan-gentamicin conjugate antimicrobial anti-inflammatory scald repair sulfated polysaccharides galactans green seaweed NMR immunostimulation inflammatory mediators carrageenan lipopolysaccharide macromolecular structure nonspecific resistance to lipopolysaccharide cytokines enteric infections salmonellosis glyceroglycolipid metabolism phosphate starvation transcriptome glyceroglycolipid homeostasis chitosan polyelectrolyte complex cytokine nitric oxide anti-inflammatory activity Ulva pertusa polysaccharides colitis antioxidant exopolysaccharide structure Vibrio alginolyticus Epidermist chitosan oligosaccharides inflammation cytokines intestine oxidative status oxidative stress Porphyridium marinum high pressure homogenizer antibacterial activity anti-biofilm activity anti-cancer activity alginate lyase cold-adapted exo/endo-type Alteromonas portus oligosaccharide antioxidant activity exopolysaccharides scandium theranostic cancer cell lines proliferation laminarin fucoidan gastrointestinal tract microbiome swine post-weaning antibiotic alternatives n/a thema EDItEUR::M Medicine and Nursing |
| topic_facet | chitosan-gentamicin conjugate antimicrobial anti-inflammatory scald repair sulfated polysaccharides galactans green seaweed NMR immunostimulation inflammatory mediators carrageenan lipopolysaccharide macromolecular structure nonspecific resistance to lipopolysaccharide cytokines enteric infections salmonellosis glyceroglycolipid metabolism phosphate starvation transcriptome glyceroglycolipid homeostasis chitosan polyelectrolyte complex cytokine nitric oxide anti-inflammatory activity Ulva pertusa polysaccharides colitis antioxidant exopolysaccharide structure Vibrio alginolyticus Epidermist chitosan oligosaccharides inflammation cytokines intestine oxidative status oxidative stress Porphyridium marinum high pressure homogenizer antibacterial activity anti-biofilm activity anti-cancer activity alginate lyase cold-adapted exo/endo-type Alteromonas portus oligosaccharide antioxidant activity exopolysaccharides scandium theranostic cancer cell lines proliferation laminarin fucoidan gastrointestinal tract microbiome swine post-weaning antibiotic alternatives n/a thema EDItEUR::M Medicine and Nursing |
| url | ONIX_20220111_9783036520919_754 |