The Theoretical Foundation of Dendritic Function

This collection of fifteen previously published papers, some of them not widely available, have been carefully chosen and annotated by Rall's colleagues and other leading neuroscientists. Wilfrid Rall was a pioneer in establishing the integrative functions of neuronal dendrites that have provided a...

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Jezik:engleski
Izdano: The MIT Press 2022
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collection Directory of Open Access Books
description This collection of fifteen previously published papers, some of them not widely available, have been carefully chosen and annotated by Rall's colleagues and other leading neuroscientists. Wilfrid Rall was a pioneer in establishing the integrative functions of neuronal dendrites that have provided a foundation for neurobiology in general and computational neuroscience in particular. This collection of fifteen previously published papers, some of them not widely available, have been carefully chosen and annotated by Rall's colleagues and other leading neuroscientists. It brings together Rall's work over more than forty years, including his first papers extending cable theory to complex dendritic trees, his ground-breaking paper introducing compartmental analysis to computational neuroscience, and his studies of synaptic integration in motoneurons, dendrodendritic interactions, plasticity of dendritic spines, and active dendritic properties. Today it is well known that the brain's synaptic information is processed mostly in the dendrites where many of the plastic changes underlying learning and memory take place. It is particularly timely to look again at the work of a major creator of the field, to appreciate where things started and where they have led, and to correct any misinterpretations of Rall's work. The editors' introduction highlights the major insights that were gained from Rall's studies as well as from those of his collaborators and followers. It asks the questions that Rall proposed during his scientific career and briefly summarizes the answers. The papers include commentaries by Milton Brightman, Robert E. Burke, William R. Holmes, Donald R. Humphrey, Julian J. B. Jack, John Miller, Stephen Redman, John Rinzel, Idan Segev, Gordon M. Shepherd, and Charles Wilson.
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spelling doab-20.500.12854ir-785002024-04-01T14:15:12Z The Theoretical Foundation of Dendritic Function Segev, Idan Rinzel, John Shepherd, Gordon M. Neurology and clinical neurophysiology thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKJ Neurology and clinical neurophysiology This collection of fifteen previously published papers, some of them not widely available, have been carefully chosen and annotated by Rall's colleagues and other leading neuroscientists. Wilfrid Rall was a pioneer in establishing the integrative functions of neuronal dendrites that have provided a foundation for neurobiology in general and computational neuroscience in particular. This collection of fifteen previously published papers, some of them not widely available, have been carefully chosen and annotated by Rall's colleagues and other leading neuroscientists. It brings together Rall's work over more than forty years, including his first papers extending cable theory to complex dendritic trees, his ground-breaking paper introducing compartmental analysis to computational neuroscience, and his studies of synaptic integration in motoneurons, dendrodendritic interactions, plasticity of dendritic spines, and active dendritic properties. Today it is well known that the brain's synaptic information is processed mostly in the dendrites where many of the plastic changes underlying learning and memory take place. It is particularly timely to look again at the work of a major creator of the field, to appreciate where things started and where they have led, and to correct any misinterpretations of Rall's work. The editors' introduction highlights the major insights that were gained from Rall's studies as well as from those of his collaborators and followers. It asks the questions that Rall proposed during his scientific career and briefly summarizes the answers. The papers include commentaries by Milton Brightman, Robert E. Burke, William R. Holmes, Donald R. Humphrey, Julian J. B. Jack, John Miller, Stephen Redman, John Rinzel, Idan Segev, Gordon M. Shepherd, and Charles Wilson. 2022-02-21T15:10:00Z 2022-02-21T15:10:00Z 2003 book ONIX_20220221_9780262283373_20 9780262283373 9780262193566 https://directory.doabooks.org/handle/20.500.12854/78500 eng Computational Neuroscience Series image/jpeg n/a https://doi.org/10.7551/mitpress/6743.001.0001 The MIT Press A Bradford Book 10.7551/mitpress/6743.001.0001 10.7551/mitpress/6743.001.0001 ae0cf962-f685-4933-93d1-916defa5123d 9780262283373 9780262193566 A Bradford Book 468 Cambridge open access
spellingShingle Neurology and clinical neurophysiology
thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKJ Neurology and clinical neurophysiology
The Theoretical Foundation of Dendritic Function
title The Theoretical Foundation of Dendritic Function
title_full The Theoretical Foundation of Dendritic Function
title_fullStr The Theoretical Foundation of Dendritic Function
title_full_unstemmed The Theoretical Foundation of Dendritic Function
title_short The Theoretical Foundation of Dendritic Function
title_sort theoretical foundation of dendritic function
topic Neurology and clinical neurophysiology
thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKJ Neurology and clinical neurophysiology
topic_facet Neurology and clinical neurophysiology
thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKJ Neurology and clinical neurophysiology
url ONIX_20220221_9780262283373_20