Schizophrenia
Leading researchers address conceptual and technical issues in schizophrenia and suggest novel strategies for advancing research and treatment. Despite major advances in methodology and thousands of published studies every year, treatment outcomes in schizophrenia have not improved over the last fif...
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| Format: | Online |
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| Idioma: | anglès |
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The MIT Press
2022
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| Accés en línia: | ONIX_20220221_9780262314602_39 |
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| collection | Directory of Open Access Books |
| description | Leading researchers address conceptual and technical issues in schizophrenia and suggest novel strategies for advancing research and treatment. Despite major advances in methodology and thousands of published studies every year, treatment outcomes in schizophrenia have not improved over the last fifty years. Moreover, we still lack strategies for prevention and we do not yet understand how the interaction of genetic, developmental, and environmental factors contribute to the disorder. In this book, leading researchers consider conceptual and technical obstacles to progress in understanding schizophrenia and suggest novel strategies for advancing research and treatment. The contributors address a wide range of critical issues: the construct of schizophrenia itself; etiology, risk, prediction, and prevention; different methods of modeling the disorder; and treatment development and delivery. They identify crucial gaps in our knowledge and offer creative but feasible suggestions. These strategies include viewing schizophrenia as a heterogeneous group of conditions; adopting specific new approaches to prediction and early intervention; developing better integration of data across genetics, imaging, perception, cognition, phenomenology, and other fields; and moving toward an evidence-based, personalized approach to treatment requiring rational clinical decision-making to reduce functional disability. Contributors Robert Bittner, Robert W. Buchanan, Kristin S. Cadenhead, William T. Carpenter, Jr., Aiden Corvin, Daniel Durstewitz, André A. Fenton, Camilo de la Fuente-Sandoval, Jay A. Gingrich, Joshua A. Gordon, Chloe Gott, Peter B. Jones, René S. Kahn, Richard Keefe, Wolfgang Kelsch, James L. Kennedy, Matcheri S. Keshavan, Angus W. MacDonald III, Anil K. Malhotra, John McGrath, Andreas Meyer-Lindenberg, Kevin J. Mitchell, Bita Moghaddam, Vera A. Morgan, Craig Morgan, Kim T. Mueser, Karoly Nikolich, Patricio O'Donnell, Michael O'Donovan, William A. Phillips, Wulf Rössler, Louis Sass, Akira Sawa, Jeremy K. Seamans, Steven M. Silverstein, William Spaulding, Sharmili Sritharan, Heike Tost, Peter Uhlhaas, Aristotle Voineskos, Michèle Wessa, Leanne M. Williams, Ashley Wilson, Til Wykes |
| format | Online |
| id | doab-20.500.12854ir-78519 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2022 |
| publishDateRange | 2022 |
| publishDateSort | 2022 |
| publisher | The MIT Press |
| publisherStr | The MIT Press |
| record_format | ojs |
| spelling | doab-20.500.12854ir-785192024-03-29T08:02:50Z Schizophrenia Silverstein, Steven M. Moghaddam, Bita Wykes, Til neuropsychiatry psychiatry research schizophrenia treatment genetics public health neurodevelopmental disorder cognitive impairment prevention treatment outcomes collection risk factors neuroscience obstacles issues heterogeneity models development creative solutions heterogeneous bic Book Industry Communication::J Society & social sciences::JM Psychology::JMB Psychological methodology bic Book Industry Communication::J Society & social sciences::JM Psychology::JMP Abnormal psychology bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences thema EDItEUR::J Society and Social Sciences::JM Psychology::JMB Psychological methodology thema EDItEUR::J Society and Social Sciences::JM Psychology::JMP Abnormal psychology thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences Leading researchers address conceptual and technical issues in schizophrenia and suggest novel strategies for advancing research and treatment. Despite major advances in methodology and thousands of published studies every year, treatment outcomes in schizophrenia have not improved over the last fifty years. Moreover, we still lack strategies for prevention and we do not yet understand how the interaction of genetic, developmental, and environmental factors contribute to the disorder. In this book, leading researchers consider conceptual and technical obstacles to progress in understanding schizophrenia and suggest novel strategies for advancing research and treatment. The contributors address a wide range of critical issues: the construct of schizophrenia itself; etiology, risk, prediction, and prevention; different methods of modeling the disorder; and treatment development and delivery. They identify crucial gaps in our knowledge and offer creative but feasible suggestions. These strategies include viewing schizophrenia as a heterogeneous group of conditions; adopting specific new approaches to prediction and early intervention; developing better integration of data across genetics, imaging, perception, cognition, phenomenology, and other fields; and moving toward an evidence-based, personalized approach to treatment requiring rational clinical decision-making to reduce functional disability. Contributors Robert Bittner, Robert W. Buchanan, Kristin S. Cadenhead, William T. Carpenter, Jr., Aiden Corvin, Daniel Durstewitz, André A. Fenton, Camilo de la Fuente-Sandoval, Jay A. Gingrich, Joshua A. Gordon, Chloe Gott, Peter B. Jones, René S. Kahn, Richard Keefe, Wolfgang Kelsch, James L. Kennedy, Matcheri S. Keshavan, Angus W. MacDonald III, Anil K. Malhotra, John McGrath, Andreas Meyer-Lindenberg, Kevin J. Mitchell, Bita Moghaddam, Vera A. Morgan, Craig Morgan, Kim T. Mueser, Karoly Nikolich, Patricio O'Donnell, Michael O'Donovan, William A. Phillips, Wulf Rössler, Louis Sass, Akira Sawa, Jeremy K. Seamans, Steven M. Silverstein, William Spaulding, Sharmili Sritharan, Heike Tost, Peter Uhlhaas, Aristotle Voineskos, Michèle Wessa, Leanne M. Williams, Ashley Wilson, Til Wykes 2022-02-21T15:10:30Z 2022-02-21T15:10:30Z 2013 book ONIX_20220221_9780262314602_39 9780262314602 9780262019620 https://directory.doabooks.org/handle/20.500.12854/78519 eng Strüngmann Forum Reports image/jpeg n/a https://doi.org/10.7551/mitpress/9780262019620.001.0001 The MIT Press The MIT Press 10.7551/mitpress/9780262019620.001.0001 10.7551/mitpress/9780262019620.001.0001 ae0cf962-f685-4933-93d1-916defa5123d 9780262314602 9780262019620 The MIT Press 13 408 Cambridge open access |
| spellingShingle | neuropsychiatry psychiatry research schizophrenia treatment genetics public health neurodevelopmental disorder cognitive impairment prevention treatment outcomes collection risk factors neuroscience obstacles issues heterogeneity models development creative solutions heterogeneous bic Book Industry Communication::J Society & social sciences::JM Psychology::JMB Psychological methodology bic Book Industry Communication::J Society & social sciences::JM Psychology::JMP Abnormal psychology bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences thema EDItEUR::J Society and Social Sciences::JM Psychology::JMB Psychological methodology thema EDItEUR::J Society and Social Sciences::JM Psychology::JMP Abnormal psychology thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences Schizophrenia |
| title | Schizophrenia |
| title_full | Schizophrenia |
| title_fullStr | Schizophrenia |
| title_full_unstemmed | Schizophrenia |
| title_short | Schizophrenia |
| title_sort | schizophrenia |
| topic | neuropsychiatry psychiatry research schizophrenia treatment genetics public health neurodevelopmental disorder cognitive impairment prevention treatment outcomes collection risk factors neuroscience obstacles issues heterogeneity models development creative solutions heterogeneous bic Book Industry Communication::J Society & social sciences::JM Psychology::JMB Psychological methodology bic Book Industry Communication::J Society & social sciences::JM Psychology::JMP Abnormal psychology bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences thema EDItEUR::J Society and Social Sciences::JM Psychology::JMB Psychological methodology thema EDItEUR::J Society and Social Sciences::JM Psychology::JMP Abnormal psychology thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences |
| topic_facet | neuropsychiatry psychiatry research schizophrenia treatment genetics public health neurodevelopmental disorder cognitive impairment prevention treatment outcomes collection risk factors neuroscience obstacles issues heterogeneity models development creative solutions heterogeneous bic Book Industry Communication::J Society & social sciences::JM Psychology::JMB Psychological methodology bic Book Industry Communication::J Society & social sciences::JM Psychology::JMP Abnormal psychology bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences thema EDItEUR::J Society and Social Sciences::JM Psychology::JMB Psychological methodology thema EDItEUR::J Society and Social Sciences::JM Psychology::JMP Abnormal psychology thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences |
| url | ONIX_20220221_9780262314602_39 |