Translational Neuroscience

Experts from academia and industry discuss how to create a new, more effective translational neuroscience drawing on novel technology and recent discoveries. Today, translational neuroscience faces significant challenges. Available therapies to treat brain and nervous system disorders are extremely...

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Veröffentlicht: The MIT Press 2022
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collection Directory of Open Access Books
description Experts from academia and industry discuss how to create a new, more effective translational neuroscience drawing on novel technology and recent discoveries. Today, translational neuroscience faces significant challenges. Available therapies to treat brain and nervous system disorders are extremely limited and dated, and further development has effectively ceased. Disinvestment by the private sector occurred just as promising new technologies in genomics, stem cell biology, and neuroscience emerged to offer new possibilities. In this volume, experts from both academia and industry discuss how novel technologies and reworked translation concepts can create a more effective translational neuroscience. The contributors consider such topics as using genomics and neuroscience for better diagnostics and biomarker identification; new approaches to disease based on stem cell technology and more careful use of animal models; and greater attention to human biology and what it will take to make new therapies available for clinical use. They conclude with a conceptual roadmap for an effective and credible translational neuroscience—one informed by a disease-focused knowledge base and clinical experience. Contributors Tobias M. Böckers, Thomas Bourgeron, Karl Broich, Nils Brose, Bruce N. Cuthbert, Ilka Diester, Gül Dölen, Guoping Feng, Richard Frackowiak, Raquel E. Gur, Stephan Heckers, Franz Hefti, David M. Holtzman, Steven E. Hyman, Nancy Ip, Cynthia Joyce, Tobias Kaiser, Edward H. Koo, Walter J. Koroshetz, Katja S. Kroker, Robert C. Malenka, Isabelle Mansuy, Eliezer, Masliah, Yuan Mei, Andreas Meyer-Lindenberg, Lennart Mucke, Pierluigi Nicotera, Karoly Nikolich, Michael J. Owen, Menelas N. Pangalos, Alvaro Pascual-Leone, Joel S. Perlmutter, Trevor W. Robbins, Lee L. Rubin, Akira Sawa, Mareike Schnaars, Bernd Sommer, Maria Grazia Spillantini, Laura Spinney, Matthew W. State, Marius Wernig
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publishDate 2022
publishDateRange 2022
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spelling doab-20.500.12854ir-785382024-04-01T14:15:24Z Translational Neuroscience Nikolich, Karoly Hyman, Steven E. Strüngmann Forum Reports translational neuroscience diagnostics biomarkers thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKJ Neurology and clinical neurophysiology thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKL Psychiatry Experts from academia and industry discuss how to create a new, more effective translational neuroscience drawing on novel technology and recent discoveries. Today, translational neuroscience faces significant challenges. Available therapies to treat brain and nervous system disorders are extremely limited and dated, and further development has effectively ceased. Disinvestment by the private sector occurred just as promising new technologies in genomics, stem cell biology, and neuroscience emerged to offer new possibilities. In this volume, experts from both academia and industry discuss how novel technologies and reworked translation concepts can create a more effective translational neuroscience. The contributors consider such topics as using genomics and neuroscience for better diagnostics and biomarker identification; new approaches to disease based on stem cell technology and more careful use of animal models; and greater attention to human biology and what it will take to make new therapies available for clinical use. They conclude with a conceptual roadmap for an effective and credible translational neuroscience—one informed by a disease-focused knowledge base and clinical experience. Contributors Tobias M. Böckers, Thomas Bourgeron, Karl Broich, Nils Brose, Bruce N. Cuthbert, Ilka Diester, Gül Dölen, Guoping Feng, Richard Frackowiak, Raquel E. Gur, Stephan Heckers, Franz Hefti, David M. Holtzman, Steven E. Hyman, Nancy Ip, Cynthia Joyce, Tobias Kaiser, Edward H. Koo, Walter J. Koroshetz, Katja S. Kroker, Robert C. Malenka, Isabelle Mansuy, Eliezer, Masliah, Yuan Mei, Andreas Meyer-Lindenberg, Lennart Mucke, Pierluigi Nicotera, Karoly Nikolich, Michael J. Owen, Menelas N. Pangalos, Alvaro Pascual-Leone, Joel S. Perlmutter, Trevor W. Robbins, Lee L. Rubin, Akira Sawa, Mareike Schnaars, Bernd Sommer, Maria Grazia Spillantini, Laura Spinney, Matthew W. State, Marius Wernig 2022-02-21T15:11:04Z 2022-02-21T15:11:04Z 2015 book ONIX_20220221_9780262329859_58 9780262329859 9780262029865 https://directory.doabooks.org/handle/20.500.12854/78538 eng Strüngmann Forum Reports image/jpeg n/a https://doi.org/10.7551/mitpress/9780262029865.001.0001 The MIT Press The MIT Press 10.7551/mitpress/9780262029865.001.0001 10.7551/mitpress/9780262029865.001.0001 ae0cf962-f685-4933-93d1-916defa5123d 9780262329859 9780262029865 The MIT Press 17 320 Cambridge open access
spellingShingle Strüngmann Forum Reports
translational neuroscience
diagnostics
biomarkers
thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKJ Neurology and clinical neurophysiology
thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKL Psychiatry
Translational Neuroscience
title Translational Neuroscience
title_full Translational Neuroscience
title_fullStr Translational Neuroscience
title_full_unstemmed Translational Neuroscience
title_short Translational Neuroscience
title_sort translational neuroscience
topic Strüngmann Forum Reports
translational neuroscience
diagnostics
biomarkers
thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKJ Neurology and clinical neurophysiology
thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKL Psychiatry
topic_facet Strüngmann Forum Reports
translational neuroscience
diagnostics
biomarkers
thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKJ Neurology and clinical neurophysiology
thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKL Psychiatry
url ONIX_20220221_9780262329859_58