Diagnosis of Endometriosis

Endometriosis is defined as the presence of endometrial-like endometrial cells, glands, and stroma outside the uterus, causing a wide range of symptoms and signs, including acute and chronic pelvic pain and infertility. Endometriosis affects approximately 10% of women of reproductive age, and up to...

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Julkaistu: MDPI - Multidisciplinary Digital Publishing Institute 2022
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description Endometriosis is defined as the presence of endometrial-like endometrial cells, glands, and stroma outside the uterus, causing a wide range of symptoms and signs, including acute and chronic pelvic pain and infertility. Endometriosis affects approximately 10% of women of reproductive age, and up to 50% of infertile women. The etiopathogenesis of endometriosis still remains controversial: immune, hormonal, genetic, and epigenetic factors may be all involved, and several theories have been proposed to explain it.One of the main problems for the management of endometriosis is the significant diagnostic delay: to date, several biomarkers are currently being tested in order to provide a reliable non-invasive diagnosis in case of symptoms and signs suspicious for endometriosis.In addition, ultrasound techniques and magnetic resonance imaging are evolving rapidly, allowing for better accuracy, even with the use of artificial intelligence. Finally, new potential histological makers are helping to correlate the occurrence of endometriosis in different anatomical landmarks, supporting specific pathways to clarify the etiology of the disease.
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spelling doab-20.500.12854ir-787162024-03-31T13:09:11Z Diagnosis of Endometriosis Laganà, Antonio Simone embryo quality endometriosis blastulation rate ongoing pregnancy menopause diagnosis management malignancy vaginal fluid microbiome next generation sequencing (NGS) pathogenesis 16S rRNA rectosigmoid endometriosis three-dimensional rectal water contrast transvaginal ultrasonography computed colonography bowel stenosis bowel endometriosis intestinal segmental resection microarray transcriptomics biomarker canonical pathways survivin BIRC5 apoptosis inhibitor of apoptosis protein coagulation thrombin time activated partial thromboplastin time platelet-to-lymphocyte ratio neutrophil-to-lymphocyte ratio adenomyosis bowel rectum ovary bladder ureter abdominal wall vagina n/a thema EDItEUR::M Medicine and Nursing Endometriosis is defined as the presence of endometrial-like endometrial cells, glands, and stroma outside the uterus, causing a wide range of symptoms and signs, including acute and chronic pelvic pain and infertility. Endometriosis affects approximately 10% of women of reproductive age, and up to 50% of infertile women. The etiopathogenesis of endometriosis still remains controversial: immune, hormonal, genetic, and epigenetic factors may be all involved, and several theories have been proposed to explain it.One of the main problems for the management of endometriosis is the significant diagnostic delay: to date, several biomarkers are currently being tested in order to provide a reliable non-invasive diagnosis in case of symptoms and signs suspicious for endometriosis.In addition, ultrasound techniques and magnetic resonance imaging are evolving rapidly, allowing for better accuracy, even with the use of artificial intelligence. Finally, new potential histological makers are helping to correlate the occurrence of endometriosis in different anatomical landmarks, supporting specific pathways to clarify the etiology of the disease. 2022-02-24T10:33:59Z 2022-02-24T10:33:59Z 2022 book ONIX_20220224_9783036528007_14 9783036528007 9783036528014 https://directory.doabooks.org/handle/20.500.12854/78716 eng image/jpeg Attribution 4.0 International https://mdpi.com/books/pdfview/book/4807 https://mdpi.com/books/pdfview/book/4807 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-2800-7 10.3390/books978-3-0365-2800-7 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036528007 9783036528014 130 Basel open access
spellingShingle embryo quality
endometriosis
blastulation rate
ongoing pregnancy
menopause
diagnosis
management
malignancy
vaginal fluid
microbiome
next generation sequencing (NGS)
pathogenesis
16S rRNA
rectosigmoid endometriosis
three-dimensional rectal water contrast transvaginal ultrasonography
computed colonography
bowel stenosis
bowel endometriosis
intestinal segmental resection
microarray
transcriptomics
biomarker
canonical pathways
survivin
BIRC5
apoptosis
inhibitor of apoptosis protein
coagulation
thrombin time
activated partial thromboplastin time
platelet-to-lymphocyte ratio
neutrophil-to-lymphocyte ratio
adenomyosis
bowel
rectum
ovary
bladder
ureter
abdominal wall
vagina
n/a
thema EDItEUR::M Medicine and Nursing
Diagnosis of Endometriosis
title Diagnosis of Endometriosis
title_full Diagnosis of Endometriosis
title_fullStr Diagnosis of Endometriosis
title_full_unstemmed Diagnosis of Endometriosis
title_short Diagnosis of Endometriosis
title_sort diagnosis of endometriosis
topic embryo quality
endometriosis
blastulation rate
ongoing pregnancy
menopause
diagnosis
management
malignancy
vaginal fluid
microbiome
next generation sequencing (NGS)
pathogenesis
16S rRNA
rectosigmoid endometriosis
three-dimensional rectal water contrast transvaginal ultrasonography
computed colonography
bowel stenosis
bowel endometriosis
intestinal segmental resection
microarray
transcriptomics
biomarker
canonical pathways
survivin
BIRC5
apoptosis
inhibitor of apoptosis protein
coagulation
thrombin time
activated partial thromboplastin time
platelet-to-lymphocyte ratio
neutrophil-to-lymphocyte ratio
adenomyosis
bowel
rectum
ovary
bladder
ureter
abdominal wall
vagina
n/a
thema EDItEUR::M Medicine and Nursing
topic_facet embryo quality
endometriosis
blastulation rate
ongoing pregnancy
menopause
diagnosis
management
malignancy
vaginal fluid
microbiome
next generation sequencing (NGS)
pathogenesis
16S rRNA
rectosigmoid endometriosis
three-dimensional rectal water contrast transvaginal ultrasonography
computed colonography
bowel stenosis
bowel endometriosis
intestinal segmental resection
microarray
transcriptomics
biomarker
canonical pathways
survivin
BIRC5
apoptosis
inhibitor of apoptosis protein
coagulation
thrombin time
activated partial thromboplastin time
platelet-to-lymphocyte ratio
neutrophil-to-lymphocyte ratio
adenomyosis
bowel
rectum
ovary
bladder
ureter
abdominal wall
vagina
n/a
thema EDItEUR::M Medicine and Nursing
url ONIX_20220224_9783036528007_14