Solid Dispersions for Drug Delivery

Since their first application in the improvement of solubility of orally delivered drugs, applications of solid dispersions have considerably expanded to include cancer, infections, and inflammatory conditions. This book presents recent advancements in the development and use of solid dispersions fo...

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Formaat: Online
Taal:Engels
Gepubliceerd in: MDPI - Multidisciplinary Digital Publishing Institute 2022
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collection Directory of Open Access Books
description Since their first application in the improvement of solubility of orally delivered drugs, applications of solid dispersions have considerably expanded to include cancer, infections, and inflammatory conditions. This book presents recent advancements in the development and use of solid dispersions for different therapeutic applications. This book can be particularly useful for researchers as well as postgraduate students in formulation sciences and drug delivery. Undergraduate students will also find elements of this book very relevant to scientific fundamentals such as solubility and crystallization of amorphous materials as well as drug delivery challenges.
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institution Directory of Open Access Books
language eng
publishDate 2022
publishDateRange 2022
publishDateSort 2022
publisher MDPI - Multidisciplinary Digital Publishing Institute
publisherStr MDPI - Multidisciplinary Digital Publishing Institute
record_format ojs
spelling doab-20.500.12854ir-787262024-03-31T13:10:25Z Solid Dispersions for Drug Delivery Khutoryanskiy, Vitaliy Al-Obaidi, Hisham solid dispersions drug delivery biological applications solid dispersion delivery system polymeric carriers antichagasic activity fexofenadine hydrochloride PEG 20,000 poloxamer188 dissolution absorption green nanotechnology raloxifene nanoemulsion core-sheath nanofibers response surface methodology ex vivo drug permeation in vivo pharmacokinetic studies acalabrutinib amorphous solid dispersion acid-reducing agent bioavailability enhancement kinase inhibitor pH effect proton pump inhibitor spray drying hydrogen bonding hydrophobicity poly(N-vinyl pyrrolidone) poly(2-oxazolines) crystallinity hydrophobic drug amorphous ibuprofen drug-rich phase liquid-liquid phase separation permeability enhancement cocrystals coamorphous solubility dry powder inhalers pulmonary drug delivery acid reducing agent in silico prediction absorption modeling GastroPlus paroxetine nanosuspension oral fast dissolving film factorial design rapid release ex vivo permeation bioavailability n/a thema EDItEUR::M Medicine and Nursing thema EDItEUR::K Economics, Finance, Business and Management::KN Industry and industrial studies::KND Manufacturing industries Since their first application in the improvement of solubility of orally delivered drugs, applications of solid dispersions have considerably expanded to include cancer, infections, and inflammatory conditions. This book presents recent advancements in the development and use of solid dispersions for different therapeutic applications. This book can be particularly useful for researchers as well as postgraduate students in formulation sciences and drug delivery. Undergraduate students will also find elements of this book very relevant to scientific fundamentals such as solubility and crystallization of amorphous materials as well as drug delivery challenges. 2022-02-24T10:34:20Z 2022-02-24T10:34:20Z 2022 book ONIX_20220224_9783036526386_24 9783036526386 9783036526393 https://directory.doabooks.org/handle/20.500.12854/78726 eng image/jpeg Attribution 4.0 International https://mdpi.com/books/pdfview/book/4817 https://mdpi.com/books/pdfview/book/4817 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-2638-6 10.3390/books978-3-0365-2638-6 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036526386 9783036526393 243 Basel open access
spellingShingle solid dispersions
drug delivery
biological applications
solid dispersion
delivery system
polymeric carriers
antichagasic activity
fexofenadine hydrochloride
PEG 20,000
poloxamer188
dissolution
absorption
green nanotechnology
raloxifene
nanoemulsion
core-sheath nanofibers
response surface methodology
ex vivo drug permeation
in vivo pharmacokinetic studies
acalabrutinib
amorphous solid dispersion
acid-reducing agent
bioavailability enhancement
kinase inhibitor
pH effect
proton pump inhibitor
spray drying
hydrogen bonding
hydrophobicity
poly(N-vinyl pyrrolidone)
poly(2-oxazolines)
crystallinity
hydrophobic drug
amorphous
ibuprofen
drug-rich phase
liquid-liquid phase separation
permeability enhancement
cocrystals
coamorphous
solubility
dry powder inhalers
pulmonary drug delivery
acid reducing agent
in silico prediction
absorption modeling
GastroPlus
paroxetine
nanosuspension
oral fast dissolving film
factorial design
rapid release
ex vivo permeation
bioavailability
n/a
thema EDItEUR::M Medicine and Nursing
thema EDItEUR::K Economics, Finance, Business and Management::KN Industry and industrial studies::KND Manufacturing industries
Solid Dispersions for Drug Delivery
title Solid Dispersions for Drug Delivery
title_full Solid Dispersions for Drug Delivery
title_fullStr Solid Dispersions for Drug Delivery
title_full_unstemmed Solid Dispersions for Drug Delivery
title_short Solid Dispersions for Drug Delivery
title_sort solid dispersions for drug delivery
topic solid dispersions
drug delivery
biological applications
solid dispersion
delivery system
polymeric carriers
antichagasic activity
fexofenadine hydrochloride
PEG 20,000
poloxamer188
dissolution
absorption
green nanotechnology
raloxifene
nanoemulsion
core-sheath nanofibers
response surface methodology
ex vivo drug permeation
in vivo pharmacokinetic studies
acalabrutinib
amorphous solid dispersion
acid-reducing agent
bioavailability enhancement
kinase inhibitor
pH effect
proton pump inhibitor
spray drying
hydrogen bonding
hydrophobicity
poly(N-vinyl pyrrolidone)
poly(2-oxazolines)
crystallinity
hydrophobic drug
amorphous
ibuprofen
drug-rich phase
liquid-liquid phase separation
permeability enhancement
cocrystals
coamorphous
solubility
dry powder inhalers
pulmonary drug delivery
acid reducing agent
in silico prediction
absorption modeling
GastroPlus
paroxetine
nanosuspension
oral fast dissolving film
factorial design
rapid release
ex vivo permeation
bioavailability
n/a
thema EDItEUR::M Medicine and Nursing
thema EDItEUR::K Economics, Finance, Business and Management::KN Industry and industrial studies::KND Manufacturing industries
topic_facet solid dispersions
drug delivery
biological applications
solid dispersion
delivery system
polymeric carriers
antichagasic activity
fexofenadine hydrochloride
PEG 20,000
poloxamer188
dissolution
absorption
green nanotechnology
raloxifene
nanoemulsion
core-sheath nanofibers
response surface methodology
ex vivo drug permeation
in vivo pharmacokinetic studies
acalabrutinib
amorphous solid dispersion
acid-reducing agent
bioavailability enhancement
kinase inhibitor
pH effect
proton pump inhibitor
spray drying
hydrogen bonding
hydrophobicity
poly(N-vinyl pyrrolidone)
poly(2-oxazolines)
crystallinity
hydrophobic drug
amorphous
ibuprofen
drug-rich phase
liquid-liquid phase separation
permeability enhancement
cocrystals
coamorphous
solubility
dry powder inhalers
pulmonary drug delivery
acid reducing agent
in silico prediction
absorption modeling
GastroPlus
paroxetine
nanosuspension
oral fast dissolving film
factorial design
rapid release
ex vivo permeation
bioavailability
n/a
thema EDItEUR::M Medicine and Nursing
thema EDItEUR::K Economics, Finance, Business and Management::KN Industry and industrial studies::KND Manufacturing industries
url ONIX_20220224_9783036526386_24