Cell Death, Inflammation and Oxidative Stress in Neurodegenerative Diseases
Neurogenerative diseases encompass very different pathologies, which can be demyelinating or nondemyelinating, but which have common mechanisms such as cell death, oxidative stress and inflammation. A better understanding of these mechanisms allows the search for biomarkers and targets for new thera...
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| Materialtyp: | Online |
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| Språk: | engelska |
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MDPI - Multidisciplinary Digital Publishing Institute
2022
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| Länkar: | ONIX_20220224_9783036529110_44 |
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| _version_ | 1869518894640660480 |
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| collection | Directory of Open Access Books |
| description | Neurogenerative diseases encompass very different pathologies, which can be demyelinating or nondemyelinating, but which have common mechanisms such as cell death, oxidative stress and inflammation. A better understanding of these mechanisms allows the search for biomarkers and targets for new therapies. This special issue brings together different data on Alzheimer's disease, Parkinson's disease, and multiple sclerosis, detailing the mechanisms of cell death (necroptosis, ferroptosis), oxidative stress and inflammation but also the possibilities of neuroprotection via 5 research articles and 6 review articles. The different reviews allow us to take stock of cell death, oxidative stress and neuroinflammation in the context of neurodegenerative diseases but also in relation to other pathologies where these processes are involved. |
| format | Online |
| id | doab-20.500.12854ir-78746 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2022 |
| publishDateRange | 2022 |
| publishDateSort | 2022 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-787462024-03-30T23:22:23Z Cell Death, Inflammation and Oxidative Stress in Neurodegenerative Diseases Vejux, Anne ferroptosis cell death iron metabolism neurodegenerative diseases glutathione peroxidase 4 GSH system xc− Alzheimer’s disease Parkinson’s disease Huntington’s disease breast cystic fluid clozapine endocytosis glia neurons ROS neuroprotection neuroinflammation catechin L-α-phosphatidylcholine phosphatidylserine brain ischemia stroke microglia astrocytes T lymphocytes monocytes platelets macrophages leukocytes neutrophils MPTP necroptosis neurodegeneration small molecules hyperglycemia hyperinsulinemia S100B protein oxidative stress central nervous system (CNS) cancer type 2 diabetes (T2DM) neuropsychiatric disorders mood disorders cytokines blood-brain barrier (BBB) FLIM brain injuries traumatic diffuse axonal injury geniculate bodies mice nerve degeneration neurofilament proteins neuroglia optic tract superior colliculi synaptophysin TDP-43 proteinopathies apoptosis necrosis docosahexaenoic acid neurodegenerative disease inflammation nanomedicine n/a thema EDItEUR::M Medicine and Nursing Neurogenerative diseases encompass very different pathologies, which can be demyelinating or nondemyelinating, but which have common mechanisms such as cell death, oxidative stress and inflammation. A better understanding of these mechanisms allows the search for biomarkers and targets for new therapies. This special issue brings together different data on Alzheimer's disease, Parkinson's disease, and multiple sclerosis, detailing the mechanisms of cell death (necroptosis, ferroptosis), oxidative stress and inflammation but also the possibilities of neuroprotection via 5 research articles and 6 review articles. The different reviews allow us to take stock of cell death, oxidative stress and neuroinflammation in the context of neurodegenerative diseases but also in relation to other pathologies where these processes are involved. 2022-02-24T10:35:08Z 2022-02-24T10:35:08Z 2022 book ONIX_20220224_9783036529110_44 9783036529110 9783036529103 https://directory.doabooks.org/handle/20.500.12854/78746 eng image/jpeg Attribution 4.0 International https://mdpi.com/books/pdfview/book/4838 https://mdpi.com/books/pdfview/book/4838 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-2911-0 10.3390/books978-3-0365-2911-0 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036529110 9783036529103 232 Basel open access |
| spellingShingle | ferroptosis cell death iron metabolism neurodegenerative diseases glutathione peroxidase 4 GSH system xc− Alzheimer’s disease Parkinson’s disease Huntington’s disease breast cystic fluid clozapine endocytosis glia neurons ROS neuroprotection neuroinflammation catechin L-α-phosphatidylcholine phosphatidylserine brain ischemia stroke microglia astrocytes T lymphocytes monocytes platelets macrophages leukocytes neutrophils MPTP necroptosis neurodegeneration small molecules hyperglycemia hyperinsulinemia S100B protein oxidative stress central nervous system (CNS) cancer type 2 diabetes (T2DM) neuropsychiatric disorders mood disorders cytokines blood-brain barrier (BBB) FLIM brain injuries traumatic diffuse axonal injury geniculate bodies mice nerve degeneration neurofilament proteins neuroglia optic tract superior colliculi synaptophysin TDP-43 proteinopathies apoptosis necrosis docosahexaenoic acid neurodegenerative disease inflammation nanomedicine n/a thema EDItEUR::M Medicine and Nursing Cell Death, Inflammation and Oxidative Stress in Neurodegenerative Diseases |
| title | Cell Death, Inflammation and Oxidative Stress in Neurodegenerative Diseases |
| title_full | Cell Death, Inflammation and Oxidative Stress in Neurodegenerative Diseases |
| title_fullStr | Cell Death, Inflammation and Oxidative Stress in Neurodegenerative Diseases |
| title_full_unstemmed | Cell Death, Inflammation and Oxidative Stress in Neurodegenerative Diseases |
| title_short | Cell Death, Inflammation and Oxidative Stress in Neurodegenerative Diseases |
| title_sort | cell death inflammation and oxidative stress in neurodegenerative diseases |
| topic | ferroptosis cell death iron metabolism neurodegenerative diseases glutathione peroxidase 4 GSH system xc− Alzheimer’s disease Parkinson’s disease Huntington’s disease breast cystic fluid clozapine endocytosis glia neurons ROS neuroprotection neuroinflammation catechin L-α-phosphatidylcholine phosphatidylserine brain ischemia stroke microglia astrocytes T lymphocytes monocytes platelets macrophages leukocytes neutrophils MPTP necroptosis neurodegeneration small molecules hyperglycemia hyperinsulinemia S100B protein oxidative stress central nervous system (CNS) cancer type 2 diabetes (T2DM) neuropsychiatric disorders mood disorders cytokines blood-brain barrier (BBB) FLIM brain injuries traumatic diffuse axonal injury geniculate bodies mice nerve degeneration neurofilament proteins neuroglia optic tract superior colliculi synaptophysin TDP-43 proteinopathies apoptosis necrosis docosahexaenoic acid neurodegenerative disease inflammation nanomedicine n/a thema EDItEUR::M Medicine and Nursing |
| topic_facet | ferroptosis cell death iron metabolism neurodegenerative diseases glutathione peroxidase 4 GSH system xc− Alzheimer’s disease Parkinson’s disease Huntington’s disease breast cystic fluid clozapine endocytosis glia neurons ROS neuroprotection neuroinflammation catechin L-α-phosphatidylcholine phosphatidylserine brain ischemia stroke microglia astrocytes T lymphocytes monocytes platelets macrophages leukocytes neutrophils MPTP necroptosis neurodegeneration small molecules hyperglycemia hyperinsulinemia S100B protein oxidative stress central nervous system (CNS) cancer type 2 diabetes (T2DM) neuropsychiatric disorders mood disorders cytokines blood-brain barrier (BBB) FLIM brain injuries traumatic diffuse axonal injury geniculate bodies mice nerve degeneration neurofilament proteins neuroglia optic tract superior colliculi synaptophysin TDP-43 proteinopathies apoptosis necrosis docosahexaenoic acid neurodegenerative disease inflammation nanomedicine n/a thema EDItEUR::M Medicine and Nursing |
| url | ONIX_20220224_9783036529110_44 |