Endometriosis Research

Endometriosis is defined as the presence of endometrial-like endometrial cells, glands, and stroma outside the uterus, causing a strong inflammatory-like microenvironment in the affected tissue. The exact prevalence of endometriosis is unknown, but estimates range from 2%–10% of women of reproductiv...

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ভাষা:ইংরেজি
প্রকাশিত: MDPI - Multidisciplinary Digital Publishing Institute 2022
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অনলাইন ব্যবহার করুন:ONIX_20220224_9783036527987_98
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_version_ 1869523260179218432
collection Directory of Open Access Books
description Endometriosis is defined as the presence of endometrial-like endometrial cells, glands, and stroma outside the uterus, causing a strong inflammatory-like microenvironment in the affected tissue. The exact prevalence of endometriosis is unknown, but estimates range from 2%–10% of women of reproductive age, to 50% of infertile women. Its etiopathogenesis of endometriosis still remains controversial—immune, hormonal, genetic, and epigenetic factors may be all involved, and several theories have been proposed to explain it.This book aims to summarize recent ground-breaking studies that may open new scenarios and change the perspective of the topic, including cutting-edge elements about diagnosis, pharmacologic and surgical treatments, as well as basic/translational science (immunology, cell biology, genetics, and epigenetics) pieces of evidence, to unravel new pathways to follow for the future diagnosis and management of endometriosis, and to improve our current knowledge of its aetiology.
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language eng
publishDate 2022
publishDateRange 2022
publishDateSort 2022
publisher MDPI - Multidisciplinary Digital Publishing Institute
publisherStr MDPI - Multidisciplinary Digital Publishing Institute
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spelling doab-20.500.12854ir-788002024-03-30T23:23:08Z Endometriosis Research Laganà, Antonio Simone La Rosa, Valentina Lucia BTG1 endometriosis human endometrial stromal cells endometrium uterus purinergic signaling ATP pathogenesis genetics epigenetics immunology ion channels etiology CFTR aquaporin chloride channels biomarker angiogenesis cytokines urinary biomarkers genetic polymorphisms SNPs aetiology Mediterranean population Sardinian population peritoneal fluid microenvironment precision medicine thema EDItEUR::M Medicine and Nursing Endometriosis is defined as the presence of endometrial-like endometrial cells, glands, and stroma outside the uterus, causing a strong inflammatory-like microenvironment in the affected tissue. The exact prevalence of endometriosis is unknown, but estimates range from 2%–10% of women of reproductive age, to 50% of infertile women. Its etiopathogenesis of endometriosis still remains controversial—immune, hormonal, genetic, and epigenetic factors may be all involved, and several theories have been proposed to explain it.This book aims to summarize recent ground-breaking studies that may open new scenarios and change the perspective of the topic, including cutting-edge elements about diagnosis, pharmacologic and surgical treatments, as well as basic/translational science (immunology, cell biology, genetics, and epigenetics) pieces of evidence, to unravel new pathways to follow for the future diagnosis and management of endometriosis, and to improve our current knowledge of its aetiology. 2022-02-24T10:36:55Z 2022-02-24T10:36:55Z 2022 book ONIX_20220224_9783036527987_98 9783036527987 9783036527994 https://directory.doabooks.org/handle/20.500.12854/78800 eng image/jpeg Attribution 4.0 International https://mdpi.com/books/pdfview/book/4895 https://mdpi.com/books/pdfview/book/4895 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-2798-7 10.3390/books978-3-0365-2798-7 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036527987 9783036527994 151 Basel open access
spellingShingle BTG1
endometriosis
human endometrial stromal cells
endometrium
uterus
purinergic signaling
ATP
pathogenesis
genetics
epigenetics
immunology
ion channels
etiology
CFTR
aquaporin
chloride channels
biomarker
angiogenesis
cytokines
urinary biomarkers
genetic polymorphisms
SNPs
aetiology
Mediterranean population
Sardinian population
peritoneal fluid
microenvironment
precision medicine
thema EDItEUR::M Medicine and Nursing
Endometriosis Research
title Endometriosis Research
title_full Endometriosis Research
title_fullStr Endometriosis Research
title_full_unstemmed Endometriosis Research
title_short Endometriosis Research
title_sort endometriosis research
topic BTG1
endometriosis
human endometrial stromal cells
endometrium
uterus
purinergic signaling
ATP
pathogenesis
genetics
epigenetics
immunology
ion channels
etiology
CFTR
aquaporin
chloride channels
biomarker
angiogenesis
cytokines
urinary biomarkers
genetic polymorphisms
SNPs
aetiology
Mediterranean population
Sardinian population
peritoneal fluid
microenvironment
precision medicine
thema EDItEUR::M Medicine and Nursing
topic_facet BTG1
endometriosis
human endometrial stromal cells
endometrium
uterus
purinergic signaling
ATP
pathogenesis
genetics
epigenetics
immunology
ion channels
etiology
CFTR
aquaporin
chloride channels
biomarker
angiogenesis
cytokines
urinary biomarkers
genetic polymorphisms
SNPs
aetiology
Mediterranean population
Sardinian population
peritoneal fluid
microenvironment
precision medicine
thema EDItEUR::M Medicine and Nursing
url ONIX_20220224_9783036527987_98