Monoclonal Antibody-Directed Therapy
The book deals with therapeutic monoclonal antibodies (mAbs) broadly, and relevant topics such as challenges and opportunities, next-generation antibody products, Antibody-Drug-Conjugates (ADC), bispecifics, glycosylation, and T-cell engagers are covered. Each topic has been written by leading group...
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| Format: | Online |
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| Idioma: | anglès |
| Publicat: |
MDPI - Multidisciplinary Digital Publishing Institute
2022
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| Matèries: | |
| Accés en línia: | ONIX_20220224_9783036528724_102 |
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| _version_ | 1869526555125874688 |
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| collection | Directory of Open Access Books |
| description | The book deals with therapeutic monoclonal antibodies (mAbs) broadly, and relevant topics such as challenges and opportunities, next-generation antibody products, Antibody-Drug-Conjugates (ADC), bispecifics, glycosylation, and T-cell engagers are covered. Each topic has been written by leading groups around the world and the book should be of interest to researchers from both academia and industry. |
| format | Online |
| id | doab-20.500.12854ir-78804 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2022 |
| publishDateRange | 2022 |
| publishDateSort | 2022 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-788042024-03-31T13:10:25Z Monoclonal Antibody-Directed Therapy Kayser, Veysel Datta-Mannan, Amita therapeutic antibody stability aggregation manufacture challenges formulation antibodies site-specific conjugation bioconjugates ADC antibody-drug conjugates payloads linkers nucleic acids ADME developability glycosylation post-translational modifications pharmacokinetics effector functions antibody-dependent cell-mediated cytotoxicity complement-dependent cytotoxicity immunogenicity pharmacodynamics glycoengineering type III secretion system prophylaxis antibacterials antibiotics HIV/AIDS co-formulation high concentration analytical characterization antibody (s) T-cell engagers bispecific antibodies immunotherapy oncology antibody engineering immunological synapse thema EDItEUR::M Medicine and Nursing thema EDItEUR::K Economics, Finance, Business and Management::KN Industry and industrial studies::KND Manufacturing industries The book deals with therapeutic monoclonal antibodies (mAbs) broadly, and relevant topics such as challenges and opportunities, next-generation antibody products, Antibody-Drug-Conjugates (ADC), bispecifics, glycosylation, and T-cell engagers are covered. Each topic has been written by leading groups around the world and the book should be of interest to researchers from both academia and industry. 2022-02-24T10:37:05Z 2022-02-24T10:37:05Z 2022 book ONIX_20220224_9783036528724_102 9783036528724 9783036528731 https://directory.doabooks.org/handle/20.500.12854/78804 eng image/jpeg Attribution 4.0 International https://mdpi.com/books/pdfview/book/4899 https://mdpi.com/books/pdfview/book/4899 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-2872-4 10.3390/books978-3-0365-2872-4 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036528724 9783036528731 142 Basel open access |
| spellingShingle | therapeutic antibody stability aggregation manufacture challenges formulation antibodies site-specific conjugation bioconjugates ADC antibody-drug conjugates payloads linkers nucleic acids ADME developability glycosylation post-translational modifications pharmacokinetics effector functions antibody-dependent cell-mediated cytotoxicity complement-dependent cytotoxicity immunogenicity pharmacodynamics glycoengineering type III secretion system prophylaxis antibacterials antibiotics HIV/AIDS co-formulation high concentration analytical characterization antibody (s) T-cell engagers bispecific antibodies immunotherapy oncology antibody engineering immunological synapse thema EDItEUR::M Medicine and Nursing thema EDItEUR::K Economics, Finance, Business and Management::KN Industry and industrial studies::KND Manufacturing industries Monoclonal Antibody-Directed Therapy |
| title | Monoclonal Antibody-Directed Therapy |
| title_full | Monoclonal Antibody-Directed Therapy |
| title_fullStr | Monoclonal Antibody-Directed Therapy |
| title_full_unstemmed | Monoclonal Antibody-Directed Therapy |
| title_short | Monoclonal Antibody-Directed Therapy |
| title_sort | monoclonal antibody directed therapy |
| topic | therapeutic antibody stability aggregation manufacture challenges formulation antibodies site-specific conjugation bioconjugates ADC antibody-drug conjugates payloads linkers nucleic acids ADME developability glycosylation post-translational modifications pharmacokinetics effector functions antibody-dependent cell-mediated cytotoxicity complement-dependent cytotoxicity immunogenicity pharmacodynamics glycoengineering type III secretion system prophylaxis antibacterials antibiotics HIV/AIDS co-formulation high concentration analytical characterization antibody (s) T-cell engagers bispecific antibodies immunotherapy oncology antibody engineering immunological synapse thema EDItEUR::M Medicine and Nursing thema EDItEUR::K Economics, Finance, Business and Management::KN Industry and industrial studies::KND Manufacturing industries |
| topic_facet | therapeutic antibody stability aggregation manufacture challenges formulation antibodies site-specific conjugation bioconjugates ADC antibody-drug conjugates payloads linkers nucleic acids ADME developability glycosylation post-translational modifications pharmacokinetics effector functions antibody-dependent cell-mediated cytotoxicity complement-dependent cytotoxicity immunogenicity pharmacodynamics glycoengineering type III secretion system prophylaxis antibacterials antibiotics HIV/AIDS co-formulation high concentration analytical characterization antibody (s) T-cell engagers bispecific antibodies immunotherapy oncology antibody engineering immunological synapse thema EDItEUR::M Medicine and Nursing thema EDItEUR::K Economics, Finance, Business and Management::KN Industry and industrial studies::KND Manufacturing industries |
| url | ONIX_20220224_9783036528724_102 |