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Monoclonal Antibodies and Their Functional Fragments in Research, Diagnosis and Therapy

This book is a compendium of scientific articles submitted to a Special Issue of International Journal of Molecular Sciences, fostered by MDPI and curated by Dr. Annamaria Sandomenico and Dr. Menotti Ruvo from the Institute of Biostructure and Bioimaging of the National Research Council. All article...

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Formato: Online
Idioma:inglês
Publicado em: MDPI - Multidisciplinary Digital Publishing Institute 2022
Assuntos:
porcine deltacoronavirus
nucleocapsid
monoclonal antibodies
neurodegenerative disorders
affibody molecules
blood–brain barrier
receptor-mediated transcytosis
transferrin receptor
AL amyloidosis
CD38
anti-CD38 MoAb
Daratumumab
Isatuximab
myeloma
BCMA
bispecific T-cell engager
antibody-drug conjugates
chimeric antigen receptor T-cells
belantamab mafodotin
idecabtagene vicleucel
JNJ-68284528
Mabs
Antibody-Drug Conjugate
cancer therapy
drug targeting
payload
cross-linking
antibody fragment
Fab
scFv
E. coli
YKL-40
CHI3L1
monoclonal antibody
phage display
lung metastasis
prostate-specific membrane antigen
in vivo imaging
prostate cancer
glutamate carboxypeptidase II
NAALADase
immunization
antibody
protocol
guinea pig
cDNA
chimeric antigen receptor (CAR T)
universal CAR T
modular CAR T
universal immune receptor
CAR adaptor
adoptive immunotherapy
split CAR
bispecific
polyspecificity
pharmacokinetics
solubility
aggregation
viscosity
developability
stability
affinity
specificity
protein engineering
self-association
non-specific binding
immunogenicity
antibody fragments
single chain
amyloid
oligomer
neurotoxicity
NUsc1
thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues
Acesso em linha:ONIX_20220321_9783036531670_37
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Resumo:This book is a compendium of scientific articles submitted to a Special Issue of International Journal of Molecular Sciences, fostered by MDPI and curated by Dr. Annamaria Sandomenico and Dr. Menotti Ruvo from the Institute of Biostructure and Bioimaging of the National Research Council. All articles underwent a rigorous peer review and were selected to highlight the properties that make monoclonal antibodies and their functional fragments some of the most useful and versatile assets in therapy and diagnosis.

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