Monoclonal Antibodies and Their Functional Fragments in Research, Diagnosis and Therapy 2.0

Monoclonal antibodies (mAbs) are among the most specialised molecules for the recognition and capture of specific analytes. Hundreds of thousands of mAbs have been generated for a large number of different antigens with increasing affinity and specificity and are available for the most diverse purpo...

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प्रकाशित: MDPI - Multidisciplinary Digital Publishing Institute 2022
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ऑनलाइन पहुंच:ONIX_20220321_9783036531656_38
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collection Directory of Open Access Books
description Monoclonal antibodies (mAbs) are among the most specialised molecules for the recognition and capture of specific analytes. Hundreds of thousands of mAbs have been generated for a large number of different antigens with increasing affinity and specificity and are available for the most diverse purposes. Many of them have been validated as irreplaceable agents for diagnosis and therapy or as unique reagents for research. Others have been developed using emerging technologies that avoid the need for animal immunisation. This short book strives to gather the perspective view of the various contributing authors and to survey the new strategic assets adopted to generate novel monoclonal antibodies or surrogates, such as Fab, Fab2, ScFv and nanobodies, which have an increasing impact in biomedicine as therapeutic or diagnostic assets in various diseases.
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institution Directory of Open Access Books
language eng
publishDate 2022
publishDateRange 2022
publishDateSort 2022
publisher MDPI - Multidisciplinary Digital Publishing Institute
publisherStr MDPI - Multidisciplinary Digital Publishing Institute
record_format ojs
spelling doab-20.500.12854ir-796022024-03-28T03:33:49Z Monoclonal Antibodies and Their Functional Fragments in Research, Diagnosis and Therapy 2.0 Ruvo, Menotti Sandomenico, Annamaria PRAME mAb bio-layer interferometry epitope identification monoclonal antibody free radical protein aggregation oxidation excipient foot-and-mouth disease virus type O type A phage display antibody competitive ELISA atherosclerosis nano-emulsion magnetic resonance imaging stealth human antibody C. auris candidiasis multidrug resistance monoclonal antibodies universal antibodies cell wall passive immunization cell-based panning semi-automated cell panning FGFR3-specific antibody thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Monoclonal antibodies (mAbs) are among the most specialised molecules for the recognition and capture of specific analytes. Hundreds of thousands of mAbs have been generated for a large number of different antigens with increasing affinity and specificity and are available for the most diverse purposes. Many of them have been validated as irreplaceable agents for diagnosis and therapy or as unique reagents for research. Others have been developed using emerging technologies that avoid the need for animal immunisation. This short book strives to gather the perspective view of the various contributing authors and to survey the new strategic assets adopted to generate novel monoclonal antibodies or surrogates, such as Fab, Fab2, ScFv and nanobodies, which have an increasing impact in biomedicine as therapeutic or diagnostic assets in various diseases. 2022-03-21T16:27:46Z 2022-03-21T16:27:46Z 2022 book ONIX_20220321_9783036531656_38 9783036531656 9783036531649 https://directory.doabooks.org/handle/20.500.12854/79602 eng image/jpeg Attribution 4.0 International https://mdpi.com/books/pdfview/book/4986 https://mdpi.com/books/pdfview/book/4986 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-3164-9 10.3390/books978-3-0365-3164-9 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036531656 9783036531649 112 Basel open access
spellingShingle PRAME
mAb
bio-layer interferometry
epitope identification
monoclonal antibody
free radical
protein aggregation
oxidation
excipient
foot-and-mouth disease virus
type O
type A
phage display
antibody
competitive ELISA
atherosclerosis
nano-emulsion
magnetic resonance imaging
stealth
human antibody
C. auris
candidiasis
multidrug resistance
monoclonal antibodies
universal antibodies
cell wall
passive immunization
cell-based panning
semi-automated cell panning
FGFR3-specific antibody
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
Monoclonal Antibodies and Their Functional Fragments in Research, Diagnosis and Therapy 2.0
title Monoclonal Antibodies and Their Functional Fragments in Research, Diagnosis and Therapy 2.0
title_full Monoclonal Antibodies and Their Functional Fragments in Research, Diagnosis and Therapy 2.0
title_fullStr Monoclonal Antibodies and Their Functional Fragments in Research, Diagnosis and Therapy 2.0
title_full_unstemmed Monoclonal Antibodies and Their Functional Fragments in Research, Diagnosis and Therapy 2.0
title_short Monoclonal Antibodies and Their Functional Fragments in Research, Diagnosis and Therapy 2.0
title_sort monoclonal antibodies and their functional fragments in research diagnosis and therapy 2 0
topic PRAME
mAb
bio-layer interferometry
epitope identification
monoclonal antibody
free radical
protein aggregation
oxidation
excipient
foot-and-mouth disease virus
type O
type A
phage display
antibody
competitive ELISA
atherosclerosis
nano-emulsion
magnetic resonance imaging
stealth
human antibody
C. auris
candidiasis
multidrug resistance
monoclonal antibodies
universal antibodies
cell wall
passive immunization
cell-based panning
semi-automated cell panning
FGFR3-specific antibody
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
topic_facet PRAME
mAb
bio-layer interferometry
epitope identification
monoclonal antibody
free radical
protein aggregation
oxidation
excipient
foot-and-mouth disease virus
type O
type A
phage display
antibody
competitive ELISA
atherosclerosis
nano-emulsion
magnetic resonance imaging
stealth
human antibody
C. auris
candidiasis
multidrug resistance
monoclonal antibodies
universal antibodies
cell wall
passive immunization
cell-based panning
semi-automated cell panning
FGFR3-specific antibody
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
url ONIX_20220321_9783036531656_38