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Pharmacogenetics to Avoid Adverse Drug Reactions

Adverse drug reactions are one of the major constraints when using drugs. These adverse reactions can impact healthcare systems as strongly as many prevalent diseases. Identifying DNA variants associated with adverse drug reactions can help personalize medicine and sustain healthcare systems. This b...

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Format: Online
Sprog:engelsk
Udgivet: MDPI - Multidisciplinary Digital Publishing Institute 2022
Fag:
5-fluorouracil
capecitabine
fluoropyrimidine
thymidylate synthase
thymidylate synthase enhancer region
upstream stimulatory factor 1
adverse drug reactions
pharmacogenomics
epistasis
random forest
statin
cardiovascular disease
colorectal cancer
personalised medicine
toxicity
(es)citalopram
drug-gene-interaction
drug-drug-interaction
drug-drug-gene-interaction
the PharmLines initiative
antipsychotic agents
pharmacogenetics
cytochrome P-450 enzyme system
psychotic disorders
precision medicine
direct oral anticoagulants
clinical implementation
atorvastatin
SLCO1B1
HLA
cutaneous adverse drug reaction
SCAR
genetic polymorphism
antiepileptics
CYP450 enzymes
platelet reactivity
single-nucleotide variants
acute coronary syndrome
clopidogrel
genotype
allele
polymorphism
HLA B
CYP2C9*3
cutaneous adverse drug reactions (CADRs)
anti-epileptic drugs (AEDS)
phenytoin (PHT)
genetic risk factors
South India
India
cardiology
adverse events
guidelines
n/a
thema EDItEUR::M Medicine and Nursing
Online adgang:ONIX_20220321_9783036533445_90
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Summary:Adverse drug reactions are one of the major constraints when using drugs. These adverse reactions can impact healthcare systems as strongly as many prevalent diseases. Identifying DNA variants associated with adverse drug reactions can help personalize medicine and sustain healthcare systems. This book delves into new advances in pharmacogenetics of cardiovascular, cancer, and nervous system drugs. It may be useful for clinicians and patients to understand the basics of pharmacogenetics.

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