Natural Product Genomics and Metabolomics of Marine Bacteria

Marine organisms are a treasure trove for the discovery of novel natural products, and, thus, marine natural products have been a focus of interest for researchers for decades. Some marine bacteria are prolific producers of natural products, occurring either free-living or, as recently shown, in sym...

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Έκδοση: MDPI - Multidisciplinary Digital Publishing Institute 2022
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collection Directory of Open Access Books
description Marine organisms are a treasure trove for the discovery of novel natural products, and, thus, marine natural products have been a focus of interest for researchers for decades. Some marine bacteria are prolific producers of natural products, occurring either free-living or, as recently shown, in symbiosis with marine animals. Recent advances in DNA sequencing have led to an enormous increase in published bacterial genomes and bioinformatics tools to analyze natural product biosynthetic potential by various “genome mining” approaches. Similarly, analytical NMR and MS methods for the characterization and comparison of metabolomes of natural product producers have advanced. Novel interdisciplinary approaches combine genomics and metabolomics data for accelerated and targeted natural product discovery. This Special Issue invites articles from both genomics- and metabolomics-driven studies on marine bacteria with a focus on natural product discovery and characterization. We particularly welcome articles that combine genomics and metabolomic approaches for the dereplication and characterization of marine bacterial natural products.
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publisherStr MDPI - Multidisciplinary Digital Publishing Institute
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spelling doab-20.500.12854ir-796602024-03-30T23:22:52Z Natural Product Genomics and Metabolomics of Marine Bacteria Crüsemann, Max Moorena bouillonii marine natural products chemogeography metabolomics natural products dereplication antibiotics marine sponges plant pathogen cyclodepsipeptides marine Actinobacteria Streptomyces spp. antibiotic sea cucumber HCV Actinobacteria marine Polar genomics specialised metabolites chitin chitinase chitin degradation machinery Pseudoalteromonas secondary metabolites bacterial natural products mass spectrometry genome mining paired omics keratinases keratinolytic proteases marine-derived Streptomyces genomic comparison cyanobacteria symbionts comparative genomics biosynthetic gene clusters Indonesia biodiversity novel antibiotics drug screening bioactivity gene cluster networking GNPS enterococci genome-wide analysis bacteriocins probiotics wild marine species Neolyngbya anticancer drug discovery South China Sea wenchangamide Moorea producens CuSO4·5H2O assisted differential gDNA isolation filamentous bacteria micrococcin P1 and P2 stalked diatoms thema EDItEUR::M Medicine and Nursing Marine organisms are a treasure trove for the discovery of novel natural products, and, thus, marine natural products have been a focus of interest for researchers for decades. Some marine bacteria are prolific producers of natural products, occurring either free-living or, as recently shown, in symbiosis with marine animals. Recent advances in DNA sequencing have led to an enormous increase in published bacterial genomes and bioinformatics tools to analyze natural product biosynthetic potential by various “genome mining” approaches. Similarly, analytical NMR and MS methods for the characterization and comparison of metabolomes of natural product producers have advanced. Novel interdisciplinary approaches combine genomics and metabolomics data for accelerated and targeted natural product discovery. This Special Issue invites articles from both genomics- and metabolomics-driven studies on marine bacteria with a focus on natural product discovery and characterization. We particularly welcome articles that combine genomics and metabolomic approaches for the dereplication and characterization of marine bacterial natural products. 2022-03-21T16:29:45Z 2022-03-21T16:29:45Z 2022 book ONIX_20220321_9783036532998_96 9783036532998 9783036533001 https://directory.doabooks.org/handle/20.500.12854/79660 eng image/jpeg Attribution 4.0 International https://mdpi.com/books/pdfview/book/5045 https://mdpi.com/books/pdfview/book/5045 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-3300-1 10.3390/books978-3-0365-3300-1 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036532998 9783036533001 244 Basel open access
spellingShingle Moorena bouillonii
marine natural products
chemogeography
metabolomics
natural products
dereplication
antibiotics
marine sponges
plant pathogen
cyclodepsipeptides
marine Actinobacteria
Streptomyces spp.
antibiotic
sea cucumber
HCV
Actinobacteria
marine
Polar
genomics
specialised metabolites
chitin
chitinase
chitin degradation machinery
Pseudoalteromonas
secondary metabolites
bacterial natural products
mass spectrometry
genome mining
paired omics
keratinases
keratinolytic proteases
marine-derived Streptomyces
genomic comparison
cyanobacteria
symbionts
comparative genomics
biosynthetic gene clusters
Indonesia
biodiversity
novel antibiotics
drug screening
bioactivity
gene cluster networking
GNPS
enterococci
genome-wide analysis
bacteriocins
probiotics
wild marine species
Neolyngbya
anticancer
drug discovery
South China Sea
wenchangamide
Moorea producens
CuSO4·5H2O assisted
differential gDNA isolation
filamentous bacteria
micrococcin P1 and P2
stalked diatoms
thema EDItEUR::M Medicine and Nursing
Natural Product Genomics and Metabolomics of Marine Bacteria
title Natural Product Genomics and Metabolomics of Marine Bacteria
title_full Natural Product Genomics and Metabolomics of Marine Bacteria
title_fullStr Natural Product Genomics and Metabolomics of Marine Bacteria
title_full_unstemmed Natural Product Genomics and Metabolomics of Marine Bacteria
title_short Natural Product Genomics and Metabolomics of Marine Bacteria
title_sort natural product genomics and metabolomics of marine bacteria
topic Moorena bouillonii
marine natural products
chemogeography
metabolomics
natural products
dereplication
antibiotics
marine sponges
plant pathogen
cyclodepsipeptides
marine Actinobacteria
Streptomyces spp.
antibiotic
sea cucumber
HCV
Actinobacteria
marine
Polar
genomics
specialised metabolites
chitin
chitinase
chitin degradation machinery
Pseudoalteromonas
secondary metabolites
bacterial natural products
mass spectrometry
genome mining
paired omics
keratinases
keratinolytic proteases
marine-derived Streptomyces
genomic comparison
cyanobacteria
symbionts
comparative genomics
biosynthetic gene clusters
Indonesia
biodiversity
novel antibiotics
drug screening
bioactivity
gene cluster networking
GNPS
enterococci
genome-wide analysis
bacteriocins
probiotics
wild marine species
Neolyngbya
anticancer
drug discovery
South China Sea
wenchangamide
Moorea producens
CuSO4·5H2O assisted
differential gDNA isolation
filamentous bacteria
micrococcin P1 and P2
stalked diatoms
thema EDItEUR::M Medicine and Nursing
topic_facet Moorena bouillonii
marine natural products
chemogeography
metabolomics
natural products
dereplication
antibiotics
marine sponges
plant pathogen
cyclodepsipeptides
marine Actinobacteria
Streptomyces spp.
antibiotic
sea cucumber
HCV
Actinobacteria
marine
Polar
genomics
specialised metabolites
chitin
chitinase
chitin degradation machinery
Pseudoalteromonas
secondary metabolites
bacterial natural products
mass spectrometry
genome mining
paired omics
keratinases
keratinolytic proteases
marine-derived Streptomyces
genomic comparison
cyanobacteria
symbionts
comparative genomics
biosynthetic gene clusters
Indonesia
biodiversity
novel antibiotics
drug screening
bioactivity
gene cluster networking
GNPS
enterococci
genome-wide analysis
bacteriocins
probiotics
wild marine species
Neolyngbya
anticancer
drug discovery
South China Sea
wenchangamide
Moorea producens
CuSO4·5H2O assisted
differential gDNA isolation
filamentous bacteria
micrococcin P1 and P2
stalked diatoms
thema EDItEUR::M Medicine and Nursing
url ONIX_20220321_9783036532998_96