New Insights in the Genetics and Genomics of Adrenocortical Tumors and Pheochromocytomas

This book includes 17 papers published in the Special Issue/Article Collectoin “New Insights in the Genetics and Genomics of adrenocortical tumors and pheochromocytomas” including an editorial, 10 research papers and six review articles. Adrenal tumors represent a hot topic in contemporary endocrine...

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מידע ביבליוגרפי
פורמט:	Online
שפה:	אנגלית
יצא לאור:	MDPI - Multidisciplinary Digital Publishing Institute 2022
נושאים:	pheochromocytoma paraganglioma genetics non-coding RNA malignancy biomarker treatment adaptive metabolism adrenal gland conn adenoma fatty acid metabolism ferroptosis hyperaldosteronism metabolic reprogramming β-oxidation PPARα tumor microenvironment Next Generation Sequencing hereditary cancer endocrine tumor syndrome KCNJ5 somatic mutation pulse wave velocity aldosterone-producing adenoma adrenalectomy propensity score matching arterial stiffness pheochromocytomas paragangliomas mutations susceptibility genes driver mutations hereditary germline somatic environment variants tumor suppressor genes metastatic RNAseq next generation sequencing adrenocortical carcinoma in silico analysis machine learning bioinformatic clustering biomarker prediction aldosterone producing adenoma ATP2B3 K416-F418delinsN mutation primary aldosteronism PPGL telomeres TERT ATRX NOP10 prognostic biomarker ALT phaeochromocytoma cancer mitochondrial complex II zebrafish therapy drug discovery redox balance pathway Vitamin C mitotane H295 strains microRNA aldosterone circulating adrenocortical transcriptomics epigenetics metabolomics epidemiology genetic analysis mortality surveillance TP53 R337H genetic testing adrenocortical tumor neonatal screening screening adenoma adrenal tissue artificial intelligence neural network n/a thema EDItEUR::M Medicine and Nursing
גישה מקוונת:	ONIX_20220321_9783036533582_108
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

תיאור
סיכום:	This book includes 17 papers published in the Special Issue/Article Collectoin “New Insights in the Genetics and Genomics of adrenocortical tumors and pheochromocytomas” including an editorial, 10 research papers and six review articles. Adrenal tumors represent a hot topic in contemporary endocrine oncology. Significant advancements in the genetics of genomics of these tumors have been made in recent years, and these articles give a useful and comprehensive overview of these issues. Questions regarding molecular pathogenesis, diagnosis (biomarkers) and even treatment are discussed in the papers written by international leaders of the field. Manuscripts are focused on three main topics: i. primary aldosteronism (the most common cause of secondary endocrine hypertension), ii. adrenocortical cancer and iii. pheochromocytoma/paraganglioma, which are the tumors with the highest heritability in humans. The book is edited by Prof. Peter Igaz (Department of Endocrinology, Faculty of Medicine, Semmelweis University).

New Insights in the Genetics and Genomics of Adrenocortical Tumors and Pheochromocytomas

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