Antimicrobial Resistance and Virulence Mechanisms

The worldwide emergence of antimicrobial-resistant bacteria, specially those resistant to last-resource antibiotics, is now a common problem being defined as one of three priorities for the safeguarding of One Health by the Tripartite Alliance, which includes the World Health Organization (WHO), the...

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collection Directory of Open Access Books
description The worldwide emergence of antimicrobial-resistant bacteria, specially those resistant to last-resource antibiotics, is now a common problem being defined as one of three priorities for the safeguarding of One Health by the Tripartite Alliance, which includes the World Health Organization (WHO), the Food and Agriculture Organization (FAO) and the Office International des Epizooties (OIE). Bacteria resistance profiles, together with the expression of specific virulence markers, have a major influence on the outcomes of infectious diseases. These bacterial traits are interconnected, since not only the presence of antibiotics may influence bacterial virulence gene expression and consequently infection pathogenesis, but some virulence factors may also contribute to an increased bacterial resistance ability, as observed in biofilm-producing strains. The surveillance of important resistant and virulent clones and associated mobile genetic elements is essential for decision making in terms of mitigation measures to be applied for the prevention of such infections in both human and veterinary medicine. However, the role of natural environments as important components of the dissemination cycle of these strains has not been consider until recently. This Special Issue aims to publish manuscripts that contribute to the understanding of the impact of bacterial antimicrobial resistance and virulence in the three areas of the One Health triad–i.e., animal, human and environmental health.
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language eng
publishDate 2022
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publisher MDPI - Multidisciplinary Digital Publishing Institute
publisherStr MDPI - Multidisciplinary Digital Publishing Institute
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spelling doab-20.500.12854ir-809922024-03-28T03:31:15Z Antimicrobial Resistance and Virulence Mechanisms Oliveira, Manuela MRSA EMRSA-15 MLSB bacteremia bloodstream infections antibiotic resistance aquatic contamination probabilistic sampling San Francisco Estuary coast Pseudomonas Shewanella algae Vibrio parahaemolyticus biocide Listeria monocytogenes biofilm planktonic culture pulsed-field gel electrophoresis Escherichia coli fosfomycin nitrofurantoin antimicrobial resistance antibiotic susceptibility WGS phylogenetic analysis DNA mismatch repair system Salmonella Choleraesuis Iberian pig wild boar phylogenetic relationship plasmid replicon typing colistin carcass cfr gene fexA gene linezolid mutation pig public health S. aureus avian colibacillosis salmonellosis MDR tetA nisin mutant prevention concentration mutant selection window antimicrobial susceptibility testing horizontal gene transfer Salmonella reptiles isolation biofilms chlorhexidine gluconate wounds Gram-negative bacteria colonization infection clonal lineages resistance genes virulence factors Staphylococcus aureus skin and soft-tissue infections plasmids Panton–Valentine leucocidin thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical) The worldwide emergence of antimicrobial-resistant bacteria, specially those resistant to last-resource antibiotics, is now a common problem being defined as one of three priorities for the safeguarding of One Health by the Tripartite Alliance, which includes the World Health Organization (WHO), the Food and Agriculture Organization (FAO) and the Office International des Epizooties (OIE). Bacteria resistance profiles, together with the expression of specific virulence markers, have a major influence on the outcomes of infectious diseases. These bacterial traits are interconnected, since not only the presence of antibiotics may influence bacterial virulence gene expression and consequently infection pathogenesis, but some virulence factors may also contribute to an increased bacterial resistance ability, as observed in biofilm-producing strains. The surveillance of important resistant and virulent clones and associated mobile genetic elements is essential for decision making in terms of mitigation measures to be applied for the prevention of such infections in both human and veterinary medicine. However, the role of natural environments as important components of the dissemination cycle of these strains has not been consider until recently. This Special Issue aims to publish manuscripts that contribute to the understanding of the impact of bacterial antimicrobial resistance and virulence in the three areas of the One Health triad–i.e., animal, human and environmental health. 2022-05-06T11:20:22Z 2022-05-06T11:20:22Z 2022 book ONIX_20220506_9783036539065_58 9783036539065 9783036539058 https://directory.doabooks.org/handle/20.500.12854/80992 eng image/jpeg Attribution 4.0 International https://mdpi.com/books/pdfview/book/5333 https://mdpi.com/books/pdfview/book/5333 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-3905-8 10.3390/books978-3-0365-3905-8 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036539065 9783036539058 232 Basel open access
spellingShingle MRSA
EMRSA-15
MLSB
bacteremia
bloodstream infections
antibiotic resistance
aquatic contamination
probabilistic sampling
San Francisco Estuary
coast
Pseudomonas
Shewanella algae
Vibrio parahaemolyticus
biocide
Listeria monocytogenes
biofilm
planktonic culture
pulsed-field gel electrophoresis
Escherichia coli
fosfomycin
nitrofurantoin
antimicrobial resistance
antibiotic susceptibility
WGS
phylogenetic analysis
DNA mismatch repair system
Salmonella Choleraesuis
Iberian pig
wild boar
phylogenetic relationship
plasmid replicon typing
colistin
carcass
cfr gene
fexA gene
linezolid
mutation
pig
public health
S. aureus
avian colibacillosis
salmonellosis
MDR
tetA
nisin
mutant prevention concentration
mutant selection window
antimicrobial susceptibility testing
horizontal gene transfer
Salmonella
reptiles
isolation
biofilms
chlorhexidine gluconate
wounds
Gram-negative bacteria
colonization
infection
clonal lineages
resistance genes
virulence factors
Staphylococcus aureus
skin and soft-tissue infections
plasmids
Panton–Valentine leucocidin
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical)
Antimicrobial Resistance and Virulence Mechanisms
title Antimicrobial Resistance and Virulence Mechanisms
title_full Antimicrobial Resistance and Virulence Mechanisms
title_fullStr Antimicrobial Resistance and Virulence Mechanisms
title_full_unstemmed Antimicrobial Resistance and Virulence Mechanisms
title_short Antimicrobial Resistance and Virulence Mechanisms
title_sort antimicrobial resistance and virulence mechanisms
topic MRSA
EMRSA-15
MLSB
bacteremia
bloodstream infections
antibiotic resistance
aquatic contamination
probabilistic sampling
San Francisco Estuary
coast
Pseudomonas
Shewanella algae
Vibrio parahaemolyticus
biocide
Listeria monocytogenes
biofilm
planktonic culture
pulsed-field gel electrophoresis
Escherichia coli
fosfomycin
nitrofurantoin
antimicrobial resistance
antibiotic susceptibility
WGS
phylogenetic analysis
DNA mismatch repair system
Salmonella Choleraesuis
Iberian pig
wild boar
phylogenetic relationship
plasmid replicon typing
colistin
carcass
cfr gene
fexA gene
linezolid
mutation
pig
public health
S. aureus
avian colibacillosis
salmonellosis
MDR
tetA
nisin
mutant prevention concentration
mutant selection window
antimicrobial susceptibility testing
horizontal gene transfer
Salmonella
reptiles
isolation
biofilms
chlorhexidine gluconate
wounds
Gram-negative bacteria
colonization
infection
clonal lineages
resistance genes
virulence factors
Staphylococcus aureus
skin and soft-tissue infections
plasmids
Panton–Valentine leucocidin
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical)
topic_facet MRSA
EMRSA-15
MLSB
bacteremia
bloodstream infections
antibiotic resistance
aquatic contamination
probabilistic sampling
San Francisco Estuary
coast
Pseudomonas
Shewanella algae
Vibrio parahaemolyticus
biocide
Listeria monocytogenes
biofilm
planktonic culture
pulsed-field gel electrophoresis
Escherichia coli
fosfomycin
nitrofurantoin
antimicrobial resistance
antibiotic susceptibility
WGS
phylogenetic analysis
DNA mismatch repair system
Salmonella Choleraesuis
Iberian pig
wild boar
phylogenetic relationship
plasmid replicon typing
colistin
carcass
cfr gene
fexA gene
linezolid
mutation
pig
public health
S. aureus
avian colibacillosis
salmonellosis
MDR
tetA
nisin
mutant prevention concentration
mutant selection window
antimicrobial susceptibility testing
horizontal gene transfer
Salmonella
reptiles
isolation
biofilms
chlorhexidine gluconate
wounds
Gram-negative bacteria
colonization
infection
clonal lineages
resistance genes
virulence factors
Staphylococcus aureus
skin and soft-tissue infections
plasmids
Panton–Valentine leucocidin
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical)
url ONIX_20220506_9783036539065_58