Cancer Biomarker Research and Personalized Medicine
Biomarkers are measures of a biological state. The treatment of individual patients based on particular factors, such as biomarkers, distinguishes standard, generalized treatment plans from personalized medicine. Even though personalized medicine is applicable to most branches of medicine, the field...
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| Médium: | Online |
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| Jazyk: | angličtina |
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MDPI - Multidisciplinary Digital Publishing Institute
2022
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| On-line přístup: | ONIX_20220506_9783036539188_66 |
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Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!
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| _version_ | 1869530259205914624 |
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| collection | Directory of Open Access Books |
| description | Biomarkers are measures of a biological state. The treatment of individual patients based on particular factors, such as biomarkers, distinguishes standard, generalized treatment plans from personalized medicine. Even though personalized medicine is applicable to most branches of medicine, the field of oncology is perhaps where it is most easily employed. Cancer is a heterogeneous disease; although patients may be diagnosed histologically with the same cancer type, their tumors can comprise varying tumor microenvironments and molecular characteristics that can impact treatment response and prognosis. There has been a major drive over the past decade to try and realize personalized cancer medicine through the discovery and use of disease-specific biomarkers. This book, entitled “Cancer Biomarker Research and Personalized Medicine”, encompasses 22 publications from colleagues working on a diverse range of cancers, including prostate, breast, ovarian, head and neck, liver, gastric, bladder, colorectal, and kidney. The biomarkers assessed in these studies include genes, intracellular or secreted proteins, exosomes, DNA, RNA, miRNA, circulating tumor cells, circulating immune cells, in addition to radiomic features. |
| format | Online |
| id | doab-20.500.12854ir-81000 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2022 |
| publishDateRange | 2022 |
| publishDateSort | 2022 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-810002024-03-31T13:10:46Z Cancer Biomarker Research and Personalized Medicine Meehan, James clear cell renal cell carcinoma radiomics WHO/ISUP nuclear grade multiphasic multidetector computed tomography triple-negative breast cancer taxane chemotherapy GBP5 Akt/mTOR autophagy IL13Rα2 renal cell carcinoma JAK2 FOXO3 telmisartan ovarian cancer bioinformatics CREB1 drug perturbation lincRNA-p21 rectal cancer chemoradiotherapy colorectal cancer long non-coding RNA p53 predictive biomarker intestinal anastomosis anastomotic leak biomarkers precision medicine personalized medicine biomarker AmpliSeq DNA methylation epigenetics head and neck cancer saliva liquid biopsy meta-analysis gastric cancer middle-up-down haptoglobin glycopeptide mass spectrometry circulating tumor cells prostate cancer cancer vaccine immune response breast cancer predictive tools prognostic tools translational research IL6ST gp130 cytokine signalling tissue-based biomarkers liquid-based biomarkers radiotherapy radiosensitivity biomarkers secretome radioresistance bladder tumor lymphocyte-to-monocyte ratio peripheral blood parameters tumor recurrence transurethral resection lipidomics 1H-NMR LC-MS/MS lipoprotein subfractions lipoprotein lipase cancer biomarkers hepatocellular carcinoma p16 expression head and neck squamous cell carcinoma HPV genotyping exosomes chemoresistance comparative oncology One Health microRNA lymph node metastasis hormone-dependent carcinogenesis localized prostate cancer prognostic factors HNSCC n/a thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology Biomarkers are measures of a biological state. The treatment of individual patients based on particular factors, such as biomarkers, distinguishes standard, generalized treatment plans from personalized medicine. Even though personalized medicine is applicable to most branches of medicine, the field of oncology is perhaps where it is most easily employed. Cancer is a heterogeneous disease; although patients may be diagnosed histologically with the same cancer type, their tumors can comprise varying tumor microenvironments and molecular characteristics that can impact treatment response and prognosis. There has been a major drive over the past decade to try and realize personalized cancer medicine through the discovery and use of disease-specific biomarkers. This book, entitled “Cancer Biomarker Research and Personalized Medicine”, encompasses 22 publications from colleagues working on a diverse range of cancers, including prostate, breast, ovarian, head and neck, liver, gastric, bladder, colorectal, and kidney. The biomarkers assessed in these studies include genes, intracellular or secreted proteins, exosomes, DNA, RNA, miRNA, circulating tumor cells, circulating immune cells, in addition to radiomic features. 2022-05-06T11:20:48Z 2022-05-06T11:20:48Z 2022 book ONIX_20220506_9783036539188_66 9783036539188 9783036539171 https://directory.doabooks.org/handle/20.500.12854/81000 eng image/jpeg Attribution 4.0 International https://mdpi.com/books/pdfview/book/5341 https://mdpi.com/books/pdfview/book/5341 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-3917-1 10.3390/books978-3-0365-3917-1 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036539188 9783036539171 428 Basel open access |
| spellingShingle | clear cell renal cell carcinoma radiomics WHO/ISUP nuclear grade multiphasic multidetector computed tomography triple-negative breast cancer taxane chemotherapy GBP5 Akt/mTOR autophagy IL13Rα2 renal cell carcinoma JAK2 FOXO3 telmisartan ovarian cancer bioinformatics CREB1 drug perturbation lincRNA-p21 rectal cancer chemoradiotherapy colorectal cancer long non-coding RNA p53 predictive biomarker intestinal anastomosis anastomotic leak biomarkers precision medicine personalized medicine biomarker AmpliSeq DNA methylation epigenetics head and neck cancer saliva liquid biopsy meta-analysis gastric cancer middle-up-down haptoglobin glycopeptide mass spectrometry circulating tumor cells prostate cancer cancer vaccine immune response breast cancer predictive tools prognostic tools translational research IL6ST gp130 cytokine signalling tissue-based biomarkers liquid-based biomarkers radiotherapy radiosensitivity biomarkers secretome radioresistance bladder tumor lymphocyte-to-monocyte ratio peripheral blood parameters tumor recurrence transurethral resection lipidomics 1H-NMR LC-MS/MS lipoprotein subfractions lipoprotein lipase cancer biomarkers hepatocellular carcinoma p16 expression head and neck squamous cell carcinoma HPV genotyping exosomes chemoresistance comparative oncology One Health microRNA lymph node metastasis hormone-dependent carcinogenesis localized prostate cancer prognostic factors HNSCC n/a thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology Cancer Biomarker Research and Personalized Medicine |
| title | Cancer Biomarker Research and Personalized Medicine |
| title_full | Cancer Biomarker Research and Personalized Medicine |
| title_fullStr | Cancer Biomarker Research and Personalized Medicine |
| title_full_unstemmed | Cancer Biomarker Research and Personalized Medicine |
| title_short | Cancer Biomarker Research and Personalized Medicine |
| title_sort | cancer biomarker research and personalized medicine |
| topic | clear cell renal cell carcinoma radiomics WHO/ISUP nuclear grade multiphasic multidetector computed tomography triple-negative breast cancer taxane chemotherapy GBP5 Akt/mTOR autophagy IL13Rα2 renal cell carcinoma JAK2 FOXO3 telmisartan ovarian cancer bioinformatics CREB1 drug perturbation lincRNA-p21 rectal cancer chemoradiotherapy colorectal cancer long non-coding RNA p53 predictive biomarker intestinal anastomosis anastomotic leak biomarkers precision medicine personalized medicine biomarker AmpliSeq DNA methylation epigenetics head and neck cancer saliva liquid biopsy meta-analysis gastric cancer middle-up-down haptoglobin glycopeptide mass spectrometry circulating tumor cells prostate cancer cancer vaccine immune response breast cancer predictive tools prognostic tools translational research IL6ST gp130 cytokine signalling tissue-based biomarkers liquid-based biomarkers radiotherapy radiosensitivity biomarkers secretome radioresistance bladder tumor lymphocyte-to-monocyte ratio peripheral blood parameters tumor recurrence transurethral resection lipidomics 1H-NMR LC-MS/MS lipoprotein subfractions lipoprotein lipase cancer biomarkers hepatocellular carcinoma p16 expression head and neck squamous cell carcinoma HPV genotyping exosomes chemoresistance comparative oncology One Health microRNA lymph node metastasis hormone-dependent carcinogenesis localized prostate cancer prognostic factors HNSCC n/a thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology |
| topic_facet | clear cell renal cell carcinoma radiomics WHO/ISUP nuclear grade multiphasic multidetector computed tomography triple-negative breast cancer taxane chemotherapy GBP5 Akt/mTOR autophagy IL13Rα2 renal cell carcinoma JAK2 FOXO3 telmisartan ovarian cancer bioinformatics CREB1 drug perturbation lincRNA-p21 rectal cancer chemoradiotherapy colorectal cancer long non-coding RNA p53 predictive biomarker intestinal anastomosis anastomotic leak biomarkers precision medicine personalized medicine biomarker AmpliSeq DNA methylation epigenetics head and neck cancer saliva liquid biopsy meta-analysis gastric cancer middle-up-down haptoglobin glycopeptide mass spectrometry circulating tumor cells prostate cancer cancer vaccine immune response breast cancer predictive tools prognostic tools translational research IL6ST gp130 cytokine signalling tissue-based biomarkers liquid-based biomarkers radiotherapy radiosensitivity biomarkers secretome radioresistance bladder tumor lymphocyte-to-monocyte ratio peripheral blood parameters tumor recurrence transurethral resection lipidomics 1H-NMR LC-MS/MS lipoprotein subfractions lipoprotein lipase cancer biomarkers hepatocellular carcinoma p16 expression head and neck squamous cell carcinoma HPV genotyping exosomes chemoresistance comparative oncology One Health microRNA lymph node metastasis hormone-dependent carcinogenesis localized prostate cancer prognostic factors HNSCC n/a thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology |
| url | ONIX_20220506_9783036539188_66 |