Antimicrobial Resistance and Virulence - 2nd Volume
The worldwide dissemination of antimicrobial-resistant bacteria, particularly those resistant to last-resource antibiotics, is a common problem to which no immediate solution is foreseen. In 2017, the World Health Organization (WHO) published a list of antimicrobial-resistant "priority pathogens", w...
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| Formato: | Online |
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| Idioma: | inglés |
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MDPI - Multidisciplinary Digital Publishing Institute
2022
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| Acceso en liña: | ONIX_20220506_9783036539089_110 |
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| collection | Directory of Open Access Books |
| description | The worldwide dissemination of antimicrobial-resistant bacteria, particularly those resistant to last-resource antibiotics, is a common problem to which no immediate solution is foreseen. In 2017, the World Health Organization (WHO) published a list of antimicrobial-resistant "priority pathogens", which include a group of microorganisms with high-level resistance to multiple drugs, named ESKAPE pathogens, comprising vancomycin-resistant Enterococcus faecium (VRE), methicillin- and vancomycin-resistant Staphylococcus aureus (MRSA and VRSA), extended spectrum β-lactamase (ESBL) or carbapenem-resistant Klebsiella pneumoniae, carbapenem-resistant Acinetobacter baumannii, carbapenem-resistant Pseudomonas aeruginosa and extended spectrum β-lactamase (ESBL) or carbapenem-resistant Enterobacter spp. These bacteria also have the ability to produce several virulence factors, which have a major influence on the outcomes of infectious diseases. Bacterial resistance and virulence are interrelated, since antibiotics pressure may influence bacterial virulence gene expression and, consequently, infection pathogenesis. Additionally, some virulence factors contribute to an increased resistance ability, as observed in biofilm-producing strains. The surveillance of important resistant and virulent clones and associated mobile genetic elements is essential to decision making in terms of mitigation measures to be applied for the prevention of such infections in both human and veterinary medicine, being also relevant to address the role of natural environments as important components of the dissemination cycle of these strains. |
| format | Online |
| id | doab-20.500.12854ir-81044 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2022 |
| publishDateRange | 2022 |
| publishDateSort | 2022 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-810442024-03-28T03:31:16Z Antimicrobial Resistance and Virulence - 2nd Volume Oliveira, Manuela Silva, Elisabete biocide antibiotic resistance cross-resistance aminoglycoside adaptation biofilm pyruvate cycle mastitis staphylococci virulence factors genes antimicrobial resistance infant newborn bacteremia Gram-negative bacteria drug resistance microbial mortality microcosm Aeromonas climate change temperature pH water Acinetobacter baumannii virulence whole-genome sequencing international high-risk clones genomic epidemiology dogs Escherichia coli ESBL CTX-M-15 CTX-M-1 CTX-M-32 CTX-M-55 CTX-M-14 qAmpC CMY-2 camel domestic milk virulence genes extended-spectrum β-lactamases biofilm formation Pseudomonas aeruginosa carbapenem resistance KPC-2 plasmid diabetic foot infections Staphylococcus aureus subinhibitory concentrations virulence-related genes thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical) The worldwide dissemination of antimicrobial-resistant bacteria, particularly those resistant to last-resource antibiotics, is a common problem to which no immediate solution is foreseen. In 2017, the World Health Organization (WHO) published a list of antimicrobial-resistant "priority pathogens", which include a group of microorganisms with high-level resistance to multiple drugs, named ESKAPE pathogens, comprising vancomycin-resistant Enterococcus faecium (VRE), methicillin- and vancomycin-resistant Staphylococcus aureus (MRSA and VRSA), extended spectrum β-lactamase (ESBL) or carbapenem-resistant Klebsiella pneumoniae, carbapenem-resistant Acinetobacter baumannii, carbapenem-resistant Pseudomonas aeruginosa and extended spectrum β-lactamase (ESBL) or carbapenem-resistant Enterobacter spp. These bacteria also have the ability to produce several virulence factors, which have a major influence on the outcomes of infectious diseases. Bacterial resistance and virulence are interrelated, since antibiotics pressure may influence bacterial virulence gene expression and, consequently, infection pathogenesis. Additionally, some virulence factors contribute to an increased resistance ability, as observed in biofilm-producing strains. The surveillance of important resistant and virulent clones and associated mobile genetic elements is essential to decision making in terms of mitigation measures to be applied for the prevention of such infections in both human and veterinary medicine, being also relevant to address the role of natural environments as important components of the dissemination cycle of these strains. 2022-05-06T11:24:11Z 2022-05-06T11:24:11Z 2022 book ONIX_20220506_9783036539089_110 9783036539089 9783036539072 https://directory.doabooks.org/handle/20.500.12854/81044 eng image/jpeg Attribution 4.0 International https://mdpi.com/books/pdfview/book/5386 https://mdpi.com/books/pdfview/book/5386 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-3907-2 10.3390/books978-3-0365-3907-2 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036539089 9783036539072 156 Basel open access |
| spellingShingle | biocide antibiotic resistance cross-resistance aminoglycoside adaptation biofilm pyruvate cycle mastitis staphylococci virulence factors genes antimicrobial resistance infant newborn bacteremia Gram-negative bacteria drug resistance microbial mortality microcosm Aeromonas climate change temperature pH water Acinetobacter baumannii virulence whole-genome sequencing international high-risk clones genomic epidemiology dogs Escherichia coli ESBL CTX-M-15 CTX-M-1 CTX-M-32 CTX-M-55 CTX-M-14 qAmpC CMY-2 camel domestic milk virulence genes extended-spectrum β-lactamases biofilm formation Pseudomonas aeruginosa carbapenem resistance KPC-2 plasmid diabetic foot infections Staphylococcus aureus subinhibitory concentrations virulence-related genes thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical) Antimicrobial Resistance and Virulence - 2nd Volume |
| title | Antimicrobial Resistance and Virulence - 2nd Volume |
| title_full | Antimicrobial Resistance and Virulence - 2nd Volume |
| title_fullStr | Antimicrobial Resistance and Virulence - 2nd Volume |
| title_full_unstemmed | Antimicrobial Resistance and Virulence - 2nd Volume |
| title_short | Antimicrobial Resistance and Virulence - 2nd Volume |
| title_sort | antimicrobial resistance and virulence 2nd volume |
| topic | biocide antibiotic resistance cross-resistance aminoglycoside adaptation biofilm pyruvate cycle mastitis staphylococci virulence factors genes antimicrobial resistance infant newborn bacteremia Gram-negative bacteria drug resistance microbial mortality microcosm Aeromonas climate change temperature pH water Acinetobacter baumannii virulence whole-genome sequencing international high-risk clones genomic epidemiology dogs Escherichia coli ESBL CTX-M-15 CTX-M-1 CTX-M-32 CTX-M-55 CTX-M-14 qAmpC CMY-2 camel domestic milk virulence genes extended-spectrum β-lactamases biofilm formation Pseudomonas aeruginosa carbapenem resistance KPC-2 plasmid diabetic foot infections Staphylococcus aureus subinhibitory concentrations virulence-related genes thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical) |
| topic_facet | biocide antibiotic resistance cross-resistance aminoglycoside adaptation biofilm pyruvate cycle mastitis staphylococci virulence factors genes antimicrobial resistance infant newborn bacteremia Gram-negative bacteria drug resistance microbial mortality microcosm Aeromonas climate change temperature pH water Acinetobacter baumannii virulence whole-genome sequencing international high-risk clones genomic epidemiology dogs Escherichia coli ESBL CTX-M-15 CTX-M-1 CTX-M-32 CTX-M-55 CTX-M-14 qAmpC CMY-2 camel domestic milk virulence genes extended-spectrum β-lactamases biofilm formation Pseudomonas aeruginosa carbapenem resistance KPC-2 plasmid diabetic foot infections Staphylococcus aureus subinhibitory concentrations virulence-related genes thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical) |
| url | ONIX_20220506_9783036539089_110 |