Buchumschlag

Osteoarthritis: From Molecular Pathways to Therapeutic Advances

In this book, we have reported the most recent discoveries and updates regarding molecular pathways in osteoarthritis. In particular, the advances regarding therapeutical options, from a molecular point of view, are largely discussed.

Gespeichert in:
Format: Online
Sprache:Englisch
Veröffentlicht: MDPI - Multidisciplinary Digital Publishing Institute 2022
Schlagworte:
osteoarthritis
cartilage
type II collagen
matrix metalloproteinases
MMP-13
regulation
inhibitor
NO synthase
Interleukin-1β
chondrocytes
mitochondrial dysfunction
mesenchimal stem cells
chondrocytic commitment
autophagy
miRNAs
hydrostatic pressure
adipokines
visfatin
Wnt/β-catenin
mechanical loading
obesity
microRNA
oxidative stress
vibrational spectroscopy
near-infrared spectroscopy
infrared spectroscopy
Raman spectroscopy
early diagnosis
exercise
physical activity
nutraceuticals
dietary supplements
inflammation
aging
inflammaging
osteochondral explant culture
joint modelling
pharmacological assay
native tissue analysis
hexosamine biosynthetic pathway
cartilage trauma
post-traumatic osteoarthritis
O-GlcNAcylation
glucosamine
cell death
therapy
sex as a biological variable
whole transcriptome sequencing
molecules
TGF-β
SMAD2/3 signaling
linker modifications
meniscus
proteomics
MRM
ECM
celecoxib
glucosamine sulfate
chondroprotection
NF-κB
cytokines
chemokines
pathogenesis
biomarker
chondrocyte
IL-1β
IFNγ, IL-17
IL-4
RNA-Seq
hypertrophy
remodeling
angiogenesis
chondroitin
collagen
methylsulfonylmethane
vitamin C
vitamin D
hyaluronic acid
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
Online-Zugang:ONIX_20220506_9783036534640_181
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Zusammenfassung:In this book, we have reported the most recent discoveries and updates regarding molecular pathways in osteoarthritis. In particular, the advances regarding therapeutical options, from a molecular point of view, are largely discussed.

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