Cerebral Ischemia

Cerebral ischemia is one of the most common causes of dementia, which develops in more than half of patients after an ischemic episode. The main mechanism is thought to be pathological changes in the hippocampus, especially in the CA1 area, underlying episodic memory impairment, which is the earlies...

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Publicat: Exon Publications 2022
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collection Directory of Open Access Books
description Cerebral ischemia is one of the most common causes of dementia, which develops in more than half of patients after an ischemic episode. The main mechanism is thought to be pathological changes in the hippocampus, especially in the CA1 area, underlying episodic memory impairment, which is the earliest and most important clinical symptom of post-ischemic dementia. The 13 chapters of this book present a new picture of ischemic brain disease, synthesizing the latest data on disease mechanisms, care for patients with this disease, and potential therapeutic targets. The authors present the characteristics of cerebral ischemia from pregnancy and childhood through adolescence to adulthood. The first two chapters provide a snapshot of the anatomy of the cerebral cortex and the hippocampus, the most affected brain structures after cerebral ischemia. This is followed by nine chapters that present a comprehensive view of the pathological mechanisms of cerebral ischemia, and how a deep understanding of these pathomechanisms hold the key for the discovery and development of novel therapies to help patients affected by cerebral ischemia. Chapter 12 shares real-life experience and challenges of rehabilitating patients into the community after cerebral ischemia, and chapter 13 analyzes the social risk variations, including gender inequality, in the reintegration of post-ischemic stroke patients. Although primarily aimed at scientists and clinicians, the contents of the book will be of interest to all those who are interested in cerebral ischemia, including patients and their caregivers.
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spelling doab-20.500.12854ir-818422022-05-22T02:08:27Z Cerebral Ischemia Pluta, Ryszard Anatomy of the Cerebral Cortex; Anatomy of the Hippocampus; Genes Associated with Alzheimer’s Disease; Hypoxic-Ischemic Brain Injury; Perinatal Asphyxia; Ischemic Brain Injury; Hyperhomocysteinemia; Exosomes in Post-Ischemic Brain; Neuroinflammation in Post-Ischemic Brain; Neurovascular Reactivity in Cerebral Ischemia; Cathepsin B in Ischemia-Reperfusion Injury After Stroke; Curcumin in Post-Ischemic Brain; Treating Cerebral Ischemia; Experimental Stroke Research; Community-Based Rehabilitation in Japan; Social Risk Variation Across Reintegration of Post-Ischemic Stroke Patients MJN Cerebral ischemia is one of the most common causes of dementia, which develops in more than half of patients after an ischemic episode. The main mechanism is thought to be pathological changes in the hippocampus, especially in the CA1 area, underlying episodic memory impairment, which is the earliest and most important clinical symptom of post-ischemic dementia. The 13 chapters of this book present a new picture of ischemic brain disease, synthesizing the latest data on disease mechanisms, care for patients with this disease, and potential therapeutic targets. The authors present the characteristics of cerebral ischemia from pregnancy and childhood through adolescence to adulthood. The first two chapters provide a snapshot of the anatomy of the cerebral cortex and the hippocampus, the most affected brain structures after cerebral ischemia. This is followed by nine chapters that present a comprehensive view of the pathological mechanisms of cerebral ischemia, and how a deep understanding of these pathomechanisms hold the key for the discovery and development of novel therapies to help patients affected by cerebral ischemia. Chapter 12 shares real-life experience and challenges of rehabilitating patients into the community after cerebral ischemia, and chapter 13 analyzes the social risk variations, including gender inequality, in the reintegration of post-ischemic stroke patients. Although primarily aimed at scientists and clinicians, the contents of the book will be of interest to all those who are interested in cerebral ischemia, including patients and their caregivers. Published 2022-05-22T02:08:25Z 2022-05-22T02:08:25Z 2021-11-06 book 9780645001792 https://directory.doabooks.org/handle/20.500.12854/81842 eng image/png Attribution-NonCommercial-NoDerivatives 4.0 International https://exonpublications.com/index.php/exon/issue/view/cerebral-ischemia Exon Publications 10.36255/exonpublications.cerebralischemia.2021 10.36255/exonpublications.cerebralischemia.2021 2d6001a3-9e06-4979-bf02-6974e313eb24 9780645001792 224 Australia open access
spellingShingle Anatomy of the Cerebral Cortex; Anatomy of the Hippocampus; Genes Associated with Alzheimer’s Disease; Hypoxic-Ischemic Brain Injury; Perinatal Asphyxia; Ischemic Brain Injury; Hyperhomocysteinemia; Exosomes in Post-Ischemic Brain; Neuroinflammation in Post-Ischemic Brain; Neurovascular Reactivity in Cerebral Ischemia; Cathepsin B in Ischemia-Reperfusion Injury After Stroke; Curcumin in Post-Ischemic Brain; Treating Cerebral Ischemia; Experimental Stroke Research; Community-Based Rehabilitation in Japan; Social Risk Variation Across Reintegration of Post-Ischemic Stroke Patients
MJN
Cerebral Ischemia
title Cerebral Ischemia
title_full Cerebral Ischemia
title_fullStr Cerebral Ischemia
title_full_unstemmed Cerebral Ischemia
title_short Cerebral Ischemia
title_sort cerebral ischemia
topic Anatomy of the Cerebral Cortex; Anatomy of the Hippocampus; Genes Associated with Alzheimer’s Disease; Hypoxic-Ischemic Brain Injury; Perinatal Asphyxia; Ischemic Brain Injury; Hyperhomocysteinemia; Exosomes in Post-Ischemic Brain; Neuroinflammation in Post-Ischemic Brain; Neurovascular Reactivity in Cerebral Ischemia; Cathepsin B in Ischemia-Reperfusion Injury After Stroke; Curcumin in Post-Ischemic Brain; Treating Cerebral Ischemia; Experimental Stroke Research; Community-Based Rehabilitation in Japan; Social Risk Variation Across Reintegration of Post-Ischemic Stroke Patients
MJN
topic_facet Anatomy of the Cerebral Cortex; Anatomy of the Hippocampus; Genes Associated with Alzheimer’s Disease; Hypoxic-Ischemic Brain Injury; Perinatal Asphyxia; Ischemic Brain Injury; Hyperhomocysteinemia; Exosomes in Post-Ischemic Brain; Neuroinflammation in Post-Ischemic Brain; Neurovascular Reactivity in Cerebral Ischemia; Cathepsin B in Ischemia-Reperfusion Injury After Stroke; Curcumin in Post-Ischemic Brain; Treating Cerebral Ischemia; Experimental Stroke Research; Community-Based Rehabilitation in Japan; Social Risk Variation Across Reintegration of Post-Ischemic Stroke Patients
MJN
url https://directory.doabooks.org/handle/20.500.12854/81842