Development of optical methods for real-time whole-brain functional imaging of zebrafish neuronal activity
Each one of us in his life has, at least once, smelled the scent of roses, read one canto of Dante’s Commedia or listened to the sound of the sea from a shell. All of this is possible thanks to the astonishing capabilities of an organ, such as the brain, that allows us to collect and organize percep...
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| フォーマット: | Online |
| 言語: | 英語 |
| 出版事項: |
Firenze University Press
2022
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| 主題: | |
| オンライン･アクセス: | ONIX_20220531_9788855180702_917 |
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| _version_ | 1869531437433094144 |
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| author | Turrini, Lapo |
| author_browse | Turrini, Lapo |
| author_facet | Turrini, Lapo |
| author_sort | Turrini, Lapo |
| collection | Directory of Open Access Books |
| description | Each one of us in his life has, at least once, smelled the scent of roses, read one canto of Dante’s Commedia or listened to the sound of the sea from a shell. All of this is possible thanks to the astonishing capabilities of an organ, such as the brain, that allows us to collect and organize perceptions coming from sensory organs and to produce behavioural responses accordingly. Studying an operating brain in a non-invasive way is extremely difficult in mammals, and particularly in humans. In the last decade, a small teleost fish, zebrafish (Danio rerio), has been making its way into the field of neurosciences. The brain of a larval zebrafish is made up of 'only' 100000 neurons and it’s completely transparent, making it possible to optically access it. Here, taking advantage of the best of currently available technology, we devised optical solutions to investigate the dynamics of neuronal activity throughout the entire brain of zebrafish larvae. |
| format | Online |
| id | doab-20.500.12854ir-82393 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2022 |
| publishDateRange | 2022 |
| publishDateSort | 2022 |
| publisher | Firenze University Press |
| publisherStr | Firenze University Press |
| record_format | ojs |
| spelling | doab-20.500.12854ir-823932025-03-15T10:53:23Z Development of optical methods for real-time whole-brain functional imaging of zebrafish neuronal activity Turrini, Lapo zebrafish calcium imaging light-sheet microscopy epilepsy behaviour Each one of us in his life has, at least once, smelled the scent of roses, read one canto of Dante’s Commedia or listened to the sound of the sea from a shell. All of this is possible thanks to the astonishing capabilities of an organ, such as the brain, that allows us to collect and organize perceptions coming from sensory organs and to produce behavioural responses accordingly. Studying an operating brain in a non-invasive way is extremely difficult in mammals, and particularly in humans. In the last decade, a small teleost fish, zebrafish (Danio rerio), has been making its way into the field of neurosciences. The brain of a larval zebrafish is made up of 'only' 100000 neurons and it’s completely transparent, making it possible to optically access it. Here, taking advantage of the best of currently available technology, we devised optical solutions to investigate the dynamics of neuronal activity throughout the entire brain of zebrafish larvae. 2022-06-02T04:09:37Z 2022-06-02T04:09:37Z 2022-05-31T10:35:55Z 2020 book ONIX_20220531_9788855180702_917 OCN: 1237005600 2612-8020 https://library.oapen.org/handle/20.500.12657/55633 9788855180702 9788855180696 9788855180719 https://directory.doabooks.org/handle/20.500.12854/82393 eng Premio Tesi di Dottorato open access image/jpeg image/jpeg image/jpeg Attribution 4.0 International Attribution 4.0 International Attribution 4.0 International https://library.oapen.org/bitstream/20.500.12657/55633/1/9788855180702.pdf https://library.oapen.org/bitstream/20.500.12657/55633/1/9788855180702.pdf https://library.oapen.org/bitstream/20.500.12657/55633/1/9788855180702.pdf Firenze University Press 10.36253/978-88-5518-070-2 10.36253/978-88-5518-070-2 2ec4474d-93b1-4cfa-b313-9c6019b51b1a 9788855180702 9788855180696 9788855180719 200 Florence open access |
| spellingShingle | zebrafish calcium imaging light-sheet microscopy epilepsy behaviour Turrini, Lapo Development of optical methods for real-time whole-brain functional imaging of zebrafish neuronal activity |
| title | Development of optical methods for real-time whole-brain functional imaging of zebrafish neuronal activity |
| title_full | Development of optical methods for real-time whole-brain functional imaging of zebrafish neuronal activity |
| title_fullStr | Development of optical methods for real-time whole-brain functional imaging of zebrafish neuronal activity |
| title_full_unstemmed | Development of optical methods for real-time whole-brain functional imaging of zebrafish neuronal activity |
| title_short | Development of optical methods for real-time whole-brain functional imaging of zebrafish neuronal activity |
| title_sort | development of optical methods for real time whole brain functional imaging of zebrafish neuronal activity |
| topic | zebrafish calcium imaging light-sheet microscopy epilepsy behaviour |
| topic_facet | zebrafish calcium imaging light-sheet microscopy epilepsy behaviour |
| url | ONIX_20220531_9788855180702_917 |
| work_keys_str_mv | AT turrinilapo developmentofopticalmethodsforrealtimewholebrainfunctionalimagingofzebrafishneuronalactivity |