Cell Biology of Galectins

Galectins are a family of soluble beta-galactoside-binding proteins with diverse glycan-dependent and glycan-independent functions outside and inside the cell. There are sixteen recognized mammalian galectin genes, and their expression profiles are very different between cell types, tissues, and spe...

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Jezik:engleski
Izdano: MDPI - Multidisciplinary Digital Publishing Institute 2022
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collection Directory of Open Access Books
description Galectins are a family of soluble beta-galactoside-binding proteins with diverse glycan-dependent and glycan-independent functions outside and inside the cell. There are sixteen recognized mammalian galectin genes, and their expression profiles are very different between cell types, tissues, and species. This Special Issue covers recent progress in the field of the cell biology of galectins, relevant concepts of galectin regulatory mechanisms, and biomedical aspects of these unique multifunctional proteins.
format Online
id doab-20.500.12854ir-87447
institution Directory of Open Access Books
language eng
publishDate 2022
publishDateRange 2022
publishDateSort 2022
publisher MDPI - Multidisciplinary Digital Publishing Institute
publisherStr MDPI - Multidisciplinary Digital Publishing Institute
record_format ojs
spelling doab-20.500.12854ir-874472024-03-28T03:33:16Z Cell Biology of Galectins Timoshenko, Alexander galectin-7 p53 MMP-9 cancer gain-of-function vasculature gene expression tube formation sprouting VEGF integrins galectin extracellular matrix microenvironment Yersinia enterocolitica YopP Galectin-1 nitric oxide macrophages epithelial tissues apoptosis targeting inhibitors β-hairpin β-sandwich blood group B lectin sugar code LGALS16 placenta brain tissues cell differentiation transcription factor miRNA galectin-3 cardiac fibrosis heart failure atrial fibrillation chronic inflammation MMPs microRNAs lncRNAs pectin structure and function bioactive polysaccharides galectin-3 inhibition galacto-oligosaccharides galectins intestinal epithelial cells β-3′galactosyllactose immunomodulation mucosal immunity O-GlcNAc unconventional secretion extraembryonic endoderm n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Galectins are a family of soluble beta-galactoside-binding proteins with diverse glycan-dependent and glycan-independent functions outside and inside the cell. There are sixteen recognized mammalian galectin genes, and their expression profiles are very different between cell types, tissues, and species. This Special Issue covers recent progress in the field of the cell biology of galectins, relevant concepts of galectin regulatory mechanisms, and biomedical aspects of these unique multifunctional proteins. 2022-07-06T11:50:11Z 2022-07-06T11:50:11Z 2022 book ONIX_20220706_9783036544489_42 9783036544489 9783036544472 https://directory.doabooks.org/handle/20.500.12854/87447 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/5635 https://mdpi.com/books/pdfview/book/5635 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-4447-2 10.3390/books978-3-0365-4447-2 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036544489 9783036544472 202 Basel open access
spellingShingle galectin-7
p53
MMP-9
cancer
gain-of-function
vasculature
gene expression
tube formation
sprouting
VEGF
integrins
galectin
extracellular matrix
microenvironment
Yersinia enterocolitica
YopP
Galectin-1
nitric oxide
macrophages
epithelial tissues
apoptosis
targeting
inhibitors
β-hairpin
β-sandwich
blood group B
lectin
sugar code
LGALS16
placenta
brain tissues
cell differentiation
transcription factor
miRNA
galectin-3
cardiac fibrosis
heart failure
atrial fibrillation
chronic inflammation
MMPs
microRNAs
lncRNAs
pectin
structure and function
bioactive polysaccharides
galectin-3 inhibition
galacto-oligosaccharides
galectins
intestinal epithelial cells
β-3′galactosyllactose
immunomodulation
mucosal immunity
O-GlcNAc
unconventional secretion
extraembryonic endoderm
n/a
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
Cell Biology of Galectins
title Cell Biology of Galectins
title_full Cell Biology of Galectins
title_fullStr Cell Biology of Galectins
title_full_unstemmed Cell Biology of Galectins
title_short Cell Biology of Galectins
title_sort cell biology of galectins
topic galectin-7
p53
MMP-9
cancer
gain-of-function
vasculature
gene expression
tube formation
sprouting
VEGF
integrins
galectin
extracellular matrix
microenvironment
Yersinia enterocolitica
YopP
Galectin-1
nitric oxide
macrophages
epithelial tissues
apoptosis
targeting
inhibitors
β-hairpin
β-sandwich
blood group B
lectin
sugar code
LGALS16
placenta
brain tissues
cell differentiation
transcription factor
miRNA
galectin-3
cardiac fibrosis
heart failure
atrial fibrillation
chronic inflammation
MMPs
microRNAs
lncRNAs
pectin
structure and function
bioactive polysaccharides
galectin-3 inhibition
galacto-oligosaccharides
galectins
intestinal epithelial cells
β-3′galactosyllactose
immunomodulation
mucosal immunity
O-GlcNAc
unconventional secretion
extraembryonic endoderm
n/a
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
topic_facet galectin-7
p53
MMP-9
cancer
gain-of-function
vasculature
gene expression
tube formation
sprouting
VEGF
integrins
galectin
extracellular matrix
microenvironment
Yersinia enterocolitica
YopP
Galectin-1
nitric oxide
macrophages
epithelial tissues
apoptosis
targeting
inhibitors
β-hairpin
β-sandwich
blood group B
lectin
sugar code
LGALS16
placenta
brain tissues
cell differentiation
transcription factor
miRNA
galectin-3
cardiac fibrosis
heart failure
atrial fibrillation
chronic inflammation
MMPs
microRNAs
lncRNAs
pectin
structure and function
bioactive polysaccharides
galectin-3 inhibition
galacto-oligosaccharides
galectins
intestinal epithelial cells
β-3′galactosyllactose
immunomodulation
mucosal immunity
O-GlcNAc
unconventional secretion
extraembryonic endoderm
n/a
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
url ONIX_20220706_9783036544489_42