Hospital Acquired Infections, Multidrug Resistant (MDR) Bacteria, Alternative Approaches to Antibiotic Therapy
Bacterial resistance to known and currently used antibiotics represents a growing issue worldwide. It poses a major problem in the treatment of infectious diseases in general and hospital-acquired infections in particular. This is in part due to the overuse and misuse of antibiotics in past decades,...
שמור ב:
| פורמט: | Online |
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| שפה: | אנגלית |
| יצא לאור: |
MDPI - Multidisciplinary Digital Publishing Institute
2022
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| נושאים: | |
| גישה מקוונת: | ONIX_20220706_9783036544182_79 |
| תגים: |
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!
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| _version_ | 1869521097416769536 |
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| collection | Directory of Open Access Books |
| description | Bacterial resistance to known and currently used antibiotics represents a growing issue worldwide. It poses a major problem in the treatment of infectious diseases in general and hospital-acquired infections in particular. This is in part due to the overuse and misuse of antibiotics in past decades, which led to the selection of highly resistant bacteria and even so-called superbugs – multidrug-resistant (MDR) bacteria. Nosocomial infections, particularly, are often caused by MDR bacterial pathogens and the treatment of such infections is very complicated and extensive, often leading to various side effects, including adverse effects on the natural human microbiome. At the same time, the development of novel antibiotics is lagging with very few new ones in the pipeline. Finding viable alternatives to treat such infections may help to overcome these therapeutic issues. This publication brings novel developments in the field of bacterial resistance, mainly in the hospital settings, adequate antibiotic therapy, and identification of compounds useful to battle this growing issue. |
| format | Online |
| id | doab-20.500.12854ir-87484 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2022 |
| publishDateRange | 2022 |
| publishDateSort | 2022 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-874842024-03-31T13:10:31Z Hospital Acquired Infections, Multidrug Resistant (MDR) Bacteria, Alternative Approaches to Antibiotic Therapy Bostik, Pavel Kolar, Milan VRE GIT hemato-oncological patients clonality antibiotic stewardship resistance consumption of antibiotics clonal spread Enterococcus faecium Enterococcus faecalis linezolid resistance 23S rRNA optrA carbapenem-resistant Klebsiella pneumoniae carbapenem-resistant Acinetobacter baumannii N-acetylcysteine septic shock critically ill patients newborn infection bacteria antibiotic therapy hops C. difficile rat model Staphylococcus aureus MRSA spa typing MLST SCCmec typing clonal analysis epidemiology cancer patients duration of treatment colistin propensity score analysis multidrug-resistant Acinetobacter baumannii urinary tract infections UTIs MDR Escherichia coli Klebsiella uropathogens AMR antibiotic resistance ESBL-producing Klebsiella pneumoniae urinary tract infection clinical impact economic impact ventilator-associated pneumonia Klebsiella spp. Escherichia spp. pulsed-field gel electrophoresis (PFGE) endogenous infection methicillin-resistant porcine model methicillin-resistant Staphylococcus aureus (MRSA) long term care facilities (LTCF) multidrug resistance (MDR) enterobacterial repetitive intergenic consensus-polymerase chain reaction (ERIC-PCR) ESBL PCR primer antimicrobial resistance infection prevention and control antimicrobial stewardship hospital cluster analysis principal component analysis thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBN Public health and preventive medicine::MBNS Epidemiology and Medical statistics Bacterial resistance to known and currently used antibiotics represents a growing issue worldwide. It poses a major problem in the treatment of infectious diseases in general and hospital-acquired infections in particular. This is in part due to the overuse and misuse of antibiotics in past decades, which led to the selection of highly resistant bacteria and even so-called superbugs – multidrug-resistant (MDR) bacteria. Nosocomial infections, particularly, are often caused by MDR bacterial pathogens and the treatment of such infections is very complicated and extensive, often leading to various side effects, including adverse effects on the natural human microbiome. At the same time, the development of novel antibiotics is lagging with very few new ones in the pipeline. Finding viable alternatives to treat such infections may help to overcome these therapeutic issues. This publication brings novel developments in the field of bacterial resistance, mainly in the hospital settings, adequate antibiotic therapy, and identification of compounds useful to battle this growing issue. 2022-07-06T11:51:56Z 2022-07-06T11:51:56Z 2022 book ONIX_20220706_9783036544182_79 9783036544182 9783036544175 https://directory.doabooks.org/handle/20.500.12854/87484 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/5682 https://mdpi.com/books/pdfview/book/5682 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-4417-5 10.3390/books978-3-0365-4417-5 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036544182 9783036544175 206 Basel open access |
| spellingShingle | VRE GIT hemato-oncological patients clonality antibiotic stewardship resistance consumption of antibiotics clonal spread Enterococcus faecium Enterococcus faecalis linezolid resistance 23S rRNA optrA carbapenem-resistant Klebsiella pneumoniae carbapenem-resistant Acinetobacter baumannii N-acetylcysteine septic shock critically ill patients newborn infection bacteria antibiotic therapy hops C. difficile rat model Staphylococcus aureus MRSA spa typing MLST SCCmec typing clonal analysis epidemiology cancer patients duration of treatment colistin propensity score analysis multidrug-resistant Acinetobacter baumannii urinary tract infections UTIs MDR Escherichia coli Klebsiella uropathogens AMR antibiotic resistance ESBL-producing Klebsiella pneumoniae urinary tract infection clinical impact economic impact ventilator-associated pneumonia Klebsiella spp. Escherichia spp. pulsed-field gel electrophoresis (PFGE) endogenous infection methicillin-resistant porcine model methicillin-resistant Staphylococcus aureus (MRSA) long term care facilities (LTCF) multidrug resistance (MDR) enterobacterial repetitive intergenic consensus-polymerase chain reaction (ERIC-PCR) ESBL PCR primer antimicrobial resistance infection prevention and control antimicrobial stewardship hospital cluster analysis principal component analysis thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBN Public health and preventive medicine::MBNS Epidemiology and Medical statistics Hospital Acquired Infections, Multidrug Resistant (MDR) Bacteria, Alternative Approaches to Antibiotic Therapy |
| title | Hospital Acquired Infections, Multidrug Resistant (MDR) Bacteria, Alternative Approaches to Antibiotic Therapy |
| title_full | Hospital Acquired Infections, Multidrug Resistant (MDR) Bacteria, Alternative Approaches to Antibiotic Therapy |
| title_fullStr | Hospital Acquired Infections, Multidrug Resistant (MDR) Bacteria, Alternative Approaches to Antibiotic Therapy |
| title_full_unstemmed | Hospital Acquired Infections, Multidrug Resistant (MDR) Bacteria, Alternative Approaches to Antibiotic Therapy |
| title_short | Hospital Acquired Infections, Multidrug Resistant (MDR) Bacteria, Alternative Approaches to Antibiotic Therapy |
| title_sort | hospital acquired infections multidrug resistant mdr bacteria alternative approaches to antibiotic therapy |
| topic | VRE GIT hemato-oncological patients clonality antibiotic stewardship resistance consumption of antibiotics clonal spread Enterococcus faecium Enterococcus faecalis linezolid resistance 23S rRNA optrA carbapenem-resistant Klebsiella pneumoniae carbapenem-resistant Acinetobacter baumannii N-acetylcysteine septic shock critically ill patients newborn infection bacteria antibiotic therapy hops C. difficile rat model Staphylococcus aureus MRSA spa typing MLST SCCmec typing clonal analysis epidemiology cancer patients duration of treatment colistin propensity score analysis multidrug-resistant Acinetobacter baumannii urinary tract infections UTIs MDR Escherichia coli Klebsiella uropathogens AMR antibiotic resistance ESBL-producing Klebsiella pneumoniae urinary tract infection clinical impact economic impact ventilator-associated pneumonia Klebsiella spp. Escherichia spp. pulsed-field gel electrophoresis (PFGE) endogenous infection methicillin-resistant porcine model methicillin-resistant Staphylococcus aureus (MRSA) long term care facilities (LTCF) multidrug resistance (MDR) enterobacterial repetitive intergenic consensus-polymerase chain reaction (ERIC-PCR) ESBL PCR primer antimicrobial resistance infection prevention and control antimicrobial stewardship hospital cluster analysis principal component analysis thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBN Public health and preventive medicine::MBNS Epidemiology and Medical statistics |
| topic_facet | VRE GIT hemato-oncological patients clonality antibiotic stewardship resistance consumption of antibiotics clonal spread Enterococcus faecium Enterococcus faecalis linezolid resistance 23S rRNA optrA carbapenem-resistant Klebsiella pneumoniae carbapenem-resistant Acinetobacter baumannii N-acetylcysteine septic shock critically ill patients newborn infection bacteria antibiotic therapy hops C. difficile rat model Staphylococcus aureus MRSA spa typing MLST SCCmec typing clonal analysis epidemiology cancer patients duration of treatment colistin propensity score analysis multidrug-resistant Acinetobacter baumannii urinary tract infections UTIs MDR Escherichia coli Klebsiella uropathogens AMR antibiotic resistance ESBL-producing Klebsiella pneumoniae urinary tract infection clinical impact economic impact ventilator-associated pneumonia Klebsiella spp. Escherichia spp. pulsed-field gel electrophoresis (PFGE) endogenous infection methicillin-resistant porcine model methicillin-resistant Staphylococcus aureus (MRSA) long term care facilities (LTCF) multidrug resistance (MDR) enterobacterial repetitive intergenic consensus-polymerase chain reaction (ERIC-PCR) ESBL PCR primer antimicrobial resistance infection prevention and control antimicrobial stewardship hospital cluster analysis principal component analysis thema EDItEUR::M Medicine and Nursing thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBN Public health and preventive medicine::MBNS Epidemiology and Medical statistics |
| url | ONIX_20220706_9783036544182_79 |