Advanced Electrochemical and Opto-Electrochemical Biosensors for Quantitative Analysis of Disease Markers and Viruses

The recent global events of the SARS-CoV-2 pandemic in 2020 have alerted the world to the urgent need to develop fast, sensitive, simple, and inexpensive analytical tools that are capable of carrying out a large number of quantitative analyses, not only in centralized laboratories and core facilitie...

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יצא לאור: MDPI - Multidisciplinary Digital Publishing Institute 2022
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גישה מקוונת:ONIX_20220706_9783036544991_94
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collection Directory of Open Access Books
description The recent global events of the SARS-CoV-2 pandemic in 2020 have alerted the world to the urgent need to develop fast, sensitive, simple, and inexpensive analytical tools that are capable of carrying out a large number of quantitative analyses, not only in centralized laboratories and core facilities but also on site and for point-of-care applications. In particular, in the case of immunological tests, the required sensitivity and specificity is often lacking when carrying out large-scale screening using decentralized methods, while a centralized laboratory with qualified personnel is required for providing quantitative and reliable responses. The advantages typical of electrochemical and optical biosensors (low cost and easy transduction) can nowadays be complemented in terms of improved sensitivity by combining electrochemistry (EC) with optical techniques such as electrochemiluminescence (ECL), EC/surface-enhanced Raman spectroscopy (SERS), and EC/surface plasmon resonance (SPR). This Special Issue addresses existing knowledge gaps and aids in exploring new approaches, solutions, and applications for opto-electrochemical biosensors in the quantitative detection of disease markers, such as cancer biomarkers proteins and allergens, and pathogenic agents such as viruses. Included are seven peer-reviewed papers that cover a range of subjects and applications related to the strategies developed for early diagnosis.
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publisherStr MDPI - Multidisciplinary Digital Publishing Institute
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spelling doab-20.500.12854ir-874992024-03-28T03:31:13Z Advanced Electrochemical and Opto-Electrochemical Biosensors for Quantitative Analysis of Disease Markers and Viruses Karimian, Najmeh Polo, Federico Ugo, Paolo gold nanoparticles doxycycline tetracycline SPR biosensor signal amplification clinical diagnosis microRNA electrochemical biosensor catalysts RedOx indicator cancer biomarker electrochemical immune platform human ST2 plasma pancreatic cancer collagen type I 4,4′-thiobisbenzenethiol nanogold electrochemical impedance spectroscopy surface plasmon resonance half antibody medical diagnostic devices peptide antifouling protease biomarker bioreceptor SARS-CoV-2 detection nasopharyngeal swab saliva serum droplets amperometric biosensor neural esterase acetylcholinesterase inhibition organophosphate design optimization mathematical model flux control dimensionless n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry The recent global events of the SARS-CoV-2 pandemic in 2020 have alerted the world to the urgent need to develop fast, sensitive, simple, and inexpensive analytical tools that are capable of carrying out a large number of quantitative analyses, not only in centralized laboratories and core facilities but also on site and for point-of-care applications. In particular, in the case of immunological tests, the required sensitivity and specificity is often lacking when carrying out large-scale screening using decentralized methods, while a centralized laboratory with qualified personnel is required for providing quantitative and reliable responses. The advantages typical of electrochemical and optical biosensors (low cost and easy transduction) can nowadays be complemented in terms of improved sensitivity by combining electrochemistry (EC) with optical techniques such as electrochemiluminescence (ECL), EC/surface-enhanced Raman spectroscopy (SERS), and EC/surface plasmon resonance (SPR). This Special Issue addresses existing knowledge gaps and aids in exploring new approaches, solutions, and applications for opto-electrochemical biosensors in the quantitative detection of disease markers, such as cancer biomarkers proteins and allergens, and pathogenic agents such as viruses. Included are seven peer-reviewed papers that cover a range of subjects and applications related to the strategies developed for early diagnosis. 2022-07-06T11:52:55Z 2022-07-06T11:52:55Z 2022 book ONIX_20220706_9783036544991_94 9783036544991 9783036545004 https://directory.doabooks.org/handle/20.500.12854/87499 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/5697 https://mdpi.com/books/pdfview/book/5697 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-4500-4 10.3390/books978-3-0365-4500-4 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036544991 9783036545004 166 Basel open access
spellingShingle gold nanoparticles
doxycycline
tetracycline
SPR biosensor
signal amplification
clinical diagnosis
microRNA
electrochemical biosensor
catalysts
RedOx indicator
cancer biomarker
electrochemical immune platform
human ST2
plasma
pancreatic cancer
collagen type I
4,4′-thiobisbenzenethiol
nanogold
electrochemical impedance spectroscopy
surface plasmon resonance
half antibody
medical diagnostic devices
peptide
antifouling
protease
biomarker
bioreceptor
SARS-CoV-2 detection
nasopharyngeal swab
saliva
serum
droplets
amperometric biosensor
neural esterase
acetylcholinesterase
inhibition
organophosphate
design
optimization
mathematical model
flux control
dimensionless
n/a
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
Advanced Electrochemical and Opto-Electrochemical Biosensors for Quantitative Analysis of Disease Markers and Viruses
title Advanced Electrochemical and Opto-Electrochemical Biosensors for Quantitative Analysis of Disease Markers and Viruses
title_full Advanced Electrochemical and Opto-Electrochemical Biosensors for Quantitative Analysis of Disease Markers and Viruses
title_fullStr Advanced Electrochemical and Opto-Electrochemical Biosensors for Quantitative Analysis of Disease Markers and Viruses
title_full_unstemmed Advanced Electrochemical and Opto-Electrochemical Biosensors for Quantitative Analysis of Disease Markers and Viruses
title_short Advanced Electrochemical and Opto-Electrochemical Biosensors for Quantitative Analysis of Disease Markers and Viruses
title_sort advanced electrochemical and opto electrochemical biosensors for quantitative analysis of disease markers and viruses
topic gold nanoparticles
doxycycline
tetracycline
SPR biosensor
signal amplification
clinical diagnosis
microRNA
electrochemical biosensor
catalysts
RedOx indicator
cancer biomarker
electrochemical immune platform
human ST2
plasma
pancreatic cancer
collagen type I
4,4′-thiobisbenzenethiol
nanogold
electrochemical impedance spectroscopy
surface plasmon resonance
half antibody
medical diagnostic devices
peptide
antifouling
protease
biomarker
bioreceptor
SARS-CoV-2 detection
nasopharyngeal swab
saliva
serum
droplets
amperometric biosensor
neural esterase
acetylcholinesterase
inhibition
organophosphate
design
optimization
mathematical model
flux control
dimensionless
n/a
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
topic_facet gold nanoparticles
doxycycline
tetracycline
SPR biosensor
signal amplification
clinical diagnosis
microRNA
electrochemical biosensor
catalysts
RedOx indicator
cancer biomarker
electrochemical immune platform
human ST2
plasma
pancreatic cancer
collagen type I
4,4′-thiobisbenzenethiol
nanogold
electrochemical impedance spectroscopy
surface plasmon resonance
half antibody
medical diagnostic devices
peptide
antifouling
protease
biomarker
bioreceptor
SARS-CoV-2 detection
nasopharyngeal swab
saliva
serum
droplets
amperometric biosensor
neural esterase
acetylcholinesterase
inhibition
organophosphate
design
optimization
mathematical model
flux control
dimensionless
n/a
thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
url ONIX_20220706_9783036544991_94