Redox-Active Molecules as Therapeutic Agents
Oxidative stress and altered redox signaling have been described in a plethora of pathological conditions. Redox-active molecules can thus potentially be used to modulate the etiology/progression of such diseases. Recent advances in molecular biology and pharmacology have strengthened this area of r...
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| Формат: | Online |
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| Язык: | английский |
| Опубликовано: |
MDPI - Multidisciplinary Digital Publishing Institute
2022
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| Предметы: | |
| Online-ссылка: | ONIX_20220706_9783036543819_134 |
| Метки: |
Нет меток, Требуется 1-ая метка записи!
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| _version_ | 1869527685152112640 |
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| collection | Directory of Open Access Books |
| description | Oxidative stress and altered redox signaling have been described in a plethora of pathological conditions. Redox-active molecules can thus potentially be used to modulate the etiology/progression of such diseases. Recent advances in molecular biology and pharmacology have strengthened this area of research by providing novel mechanistic insights. This book compiles a collection of 13 articles, covering a range of topics from in vitro studies to clinical research, focused on the potential therapeutic effects of either natural or synthetic compounds, applicable to different redox-related diseases. |
| format | Online |
| id | doab-20.500.12854ir-87539 |
| institution | Directory of Open Access Books |
| language | eng |
| publishDate | 2022 |
| publishDateRange | 2022 |
| publishDateSort | 2022 |
| publisher | MDPI - Multidisciplinary Digital Publishing Institute |
| publisherStr | MDPI - Multidisciplinary Digital Publishing Institute |
| record_format | ojs |
| spelling | doab-20.500.12854ir-875392024-03-28T03:33:50Z Redox-Active Molecules as Therapeutic Agents Fernandes, Ana Sofia non-small cell lung cancer cisplatin apurinic/apyrimidinic endonuclease 1 E3330 cytotoxicity apoptosis migration invasion oxidative stress sildenafil DNA damage systemic sclerosis bioactivity-based assays cyanidin metabolomics Rubus genus (poly)phenols yeast-based discovery platform withanolide breast cancer mitochondrial reactive oxygen species peroxiredoxin 3 pro-oxidant therapy thiostrepton GSH Cysteamine N-acetyl cysteine KEAP1 NRF2 ATF4 adipose-derived mesenchymal stem cell amniotic membrane-derived mesenchymal stem cell antioxidants assisted reproductive technology conditioned medium embryo in vitro culture in vitro fertilization BAPN cell invasion EMT lysyl-oxidase lysyl-oxidase like 2 metastases inhibitors doxorubicin chemoresistance redox signaling nuclear factor erythroid 2-related factor 2 (Nrf2) cancer therapy hydrogen sulfide reactive oxygen species H2S donors cardiorenal syndrome thiosulfate selenium-enriched Enterococcus faecium selenium-enriched Streptococcus thermophilus antioxidant capacity glutathione reductase glutathione peroxidase CD IGS rats lactic acid bacteria verbascoside hypercholesterolemia prostate cancer curcumin carnosic acid cell cycle OxPhos SGK1 n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Oxidative stress and altered redox signaling have been described in a plethora of pathological conditions. Redox-active molecules can thus potentially be used to modulate the etiology/progression of such diseases. Recent advances in molecular biology and pharmacology have strengthened this area of research by providing novel mechanistic insights. This book compiles a collection of 13 articles, covering a range of topics from in vitro studies to clinical research, focused on the potential therapeutic effects of either natural or synthetic compounds, applicable to different redox-related diseases. 2022-07-06T11:55:07Z 2022-07-06T11:55:07Z 2022 book ONIX_20220706_9783036543819_134 9783036543819 9783036543826 https://directory.doabooks.org/handle/20.500.12854/87539 eng application/octet-stream Attribution 4.0 International https://mdpi.com/books/pdfview/book/5737 https://mdpi.com/books/pdfview/book/5737 MDPI - Multidisciplinary Digital Publishing Institute 10.3390/books978-3-0365-4382-6 10.3390/books978-3-0365-4382-6 46cabcaa-dd94-4bfe-87b4-55023c1b36d0 9783036543819 9783036543826 266 Basel open access |
| spellingShingle | non-small cell lung cancer cisplatin apurinic/apyrimidinic endonuclease 1 E3330 cytotoxicity apoptosis migration invasion oxidative stress sildenafil DNA damage systemic sclerosis bioactivity-based assays cyanidin metabolomics Rubus genus (poly)phenols yeast-based discovery platform withanolide breast cancer mitochondrial reactive oxygen species peroxiredoxin 3 pro-oxidant therapy thiostrepton GSH Cysteamine N-acetyl cysteine KEAP1 NRF2 ATF4 adipose-derived mesenchymal stem cell amniotic membrane-derived mesenchymal stem cell antioxidants assisted reproductive technology conditioned medium embryo in vitro culture in vitro fertilization BAPN cell invasion EMT lysyl-oxidase lysyl-oxidase like 2 metastases inhibitors doxorubicin chemoresistance redox signaling nuclear factor erythroid 2-related factor 2 (Nrf2) cancer therapy hydrogen sulfide reactive oxygen species H2S donors cardiorenal syndrome thiosulfate selenium-enriched Enterococcus faecium selenium-enriched Streptococcus thermophilus antioxidant capacity glutathione reductase glutathione peroxidase CD IGS rats lactic acid bacteria verbascoside hypercholesterolemia prostate cancer curcumin carnosic acid cell cycle OxPhos SGK1 n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences Redox-Active Molecules as Therapeutic Agents |
| title | Redox-Active Molecules as Therapeutic Agents |
| title_full | Redox-Active Molecules as Therapeutic Agents |
| title_fullStr | Redox-Active Molecules as Therapeutic Agents |
| title_full_unstemmed | Redox-Active Molecules as Therapeutic Agents |
| title_short | Redox-Active Molecules as Therapeutic Agents |
| title_sort | redox active molecules as therapeutic agents |
| topic | non-small cell lung cancer cisplatin apurinic/apyrimidinic endonuclease 1 E3330 cytotoxicity apoptosis migration invasion oxidative stress sildenafil DNA damage systemic sclerosis bioactivity-based assays cyanidin metabolomics Rubus genus (poly)phenols yeast-based discovery platform withanolide breast cancer mitochondrial reactive oxygen species peroxiredoxin 3 pro-oxidant therapy thiostrepton GSH Cysteamine N-acetyl cysteine KEAP1 NRF2 ATF4 adipose-derived mesenchymal stem cell amniotic membrane-derived mesenchymal stem cell antioxidants assisted reproductive technology conditioned medium embryo in vitro culture in vitro fertilization BAPN cell invasion EMT lysyl-oxidase lysyl-oxidase like 2 metastases inhibitors doxorubicin chemoresistance redox signaling nuclear factor erythroid 2-related factor 2 (Nrf2) cancer therapy hydrogen sulfide reactive oxygen species H2S donors cardiorenal syndrome thiosulfate selenium-enriched Enterococcus faecium selenium-enriched Streptococcus thermophilus antioxidant capacity glutathione reductase glutathione peroxidase CD IGS rats lactic acid bacteria verbascoside hypercholesterolemia prostate cancer curcumin carnosic acid cell cycle OxPhos SGK1 n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| topic_facet | non-small cell lung cancer cisplatin apurinic/apyrimidinic endonuclease 1 E3330 cytotoxicity apoptosis migration invasion oxidative stress sildenafil DNA damage systemic sclerosis bioactivity-based assays cyanidin metabolomics Rubus genus (poly)phenols yeast-based discovery platform withanolide breast cancer mitochondrial reactive oxygen species peroxiredoxin 3 pro-oxidant therapy thiostrepton GSH Cysteamine N-acetyl cysteine KEAP1 NRF2 ATF4 adipose-derived mesenchymal stem cell amniotic membrane-derived mesenchymal stem cell antioxidants assisted reproductive technology conditioned medium embryo in vitro culture in vitro fertilization BAPN cell invasion EMT lysyl-oxidase lysyl-oxidase like 2 metastases inhibitors doxorubicin chemoresistance redox signaling nuclear factor erythroid 2-related factor 2 (Nrf2) cancer therapy hydrogen sulfide reactive oxygen species H2S donors cardiorenal syndrome thiosulfate selenium-enriched Enterococcus faecium selenium-enriched Streptococcus thermophilus antioxidant capacity glutathione reductase glutathione peroxidase CD IGS rats lactic acid bacteria verbascoside hypercholesterolemia prostate cancer curcumin carnosic acid cell cycle OxPhos SGK1 n/a thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general thema EDItEUR::P Mathematics and Science::PS Biology, life sciences |
| url | ONIX_20220706_9783036543819_134 |